Effects of Taxon Sampling in Reconstructions of Intron Evolution
International Journal of Genomics, 2013 Introns comprise a considerable portion of eukaryotic genomes; however, their evolution is understudied. Numerous works of the last years largely disagree on many aspects of intron evolution.
Mikhail A. Nikitin, Vladimir V. Aleoshin
doaj +1 more source
RoundMi: A quantitative method to analyze mitochondrial morphology in mitotic cells
FEBS Open Bio, EarlyView.RoundMi is a workflow for rapid analysis of mitochondrial morphology in mitotic cells. By combining adaptive preprocessing with automated segmentation and quantification, it enables accurate measurements from single focal plane images, reducing acquisition time and computational demands while remaining compatible with high‐throughput fixed and live ...
Elmira Parvindokht Bararpour +2 more
wiley +1 more source
Sub-nyquist sampling techniques [PDF]
, 1990 A number of novel theoretical methods have been developed in an attempt to analyse data produced by sampling a signal at below the Nyquist rate and the limitations of the approaches have been investigated.
Bagshaw, Paul Christopher
core
Benchmarking hybrid algorithms for distributed constraint optimisation games
, 2011 In this paper, we consider algorithms for distributed constraint optimisation problems (DCOPs). Using a potential game characterisation of DCOPs, we decompose eight DCOP algorithms, taken from the game theory and computer science literatures, into their ...
Jennings, Nick +2 more
core +1 more source
Accelerating Convergence of Stein Variational Gradient Descent via Deep Unfolding
IEEE AccessStein variational gradient descent (SVGD) is a prominent particle-based variational inference method used for sampling a target distribution. In this paper, we propose two novel trainable algorithms based on SVGD: deep-unfolded SVGD (DUSVGD) and ...
Yuya Kawamura, Satoshi Takabe
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Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes
FEBS Open Bio, EarlyView.Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard +12 more
wiley +1 more source
An Unbiased Estimator of the Variance of Simple Random Sampling Using Mixed Random-Systematic Sampling [PDF]
Systematic sampling is a commonly used technique due to its simplicity and ease of implementation. The drawback of this simplicity is that it is not possible to estimate the design variance without bias. There are several ways to circumvent this problem.
Alberto Padilla
core
Transcripts enriched in codons that trigger P‐site tRNA‐mediated mRNA decay possess stable mRNA
FEBS Open Bio, EarlyView.PTMD codons were first described by Mendel et al. as mediators of an mRNA decay pathway dependent on the human protein CNOT3, homologous to yeast Not5. Our findings confirm that PTMD codons destabilize transcripts; however, unlike in yeast, the human pathway specifically targets and slightly destabilizes primarily stable mRNAs.
Rodolfo Lopes Carneiro +1 more
wiley +1 more source
The Optimally Designed Deep Autoencoder-Based Compressive Sensing Framework for 1D and 2D Signals
IEEE AccessThe capacity of Compressive Sensing (CS) to recreate original data from a limited number of samples has led to a surge in attention in recent years.
Irfan Ahmed +3 more
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Accurate and noninvasive prostate cancer detection using plasma‐derived extracellular vesicle RNA
FEBS Open Bio, EarlyView.Plasma extracellular vesicles were captured with WGA‐conjugated magnetic beads and profiled for RNA biomarkers. A three‐RNA panel (NM_024955, NR_047469, and NR_002564) distinguished prostate cancer from healthy controls and benign prostatic hyperplasia, supporting a simple, noninvasive approach to improve prostate cancer detection.
Hanping Wei, Haoran Wu, Wei Feng
wiley +1 more source