Results 61 to 70 of about 7,951,181 (327)

Emerging role of ARHGAP29 in melanoma cell phenotype switching

open access: yesMolecular Oncology, EarlyView.
This study gives first insights into the role of ARHGAP29 in malignant melanoma. ARHGAP29 was revealed to be connected to tumor cell plasticity, promoting a mesenchymal‐like, invasive phenotype and driving tumor progression. Further, it modulates cell spreading by influencing RhoA/ROCK signaling and affects SMAD2 activity. Rho GTPase‐activating protein
Beatrice Charlotte Tröster   +3 more
wiley   +1 more source

Entre intelectuales y expertos

open access: yesAustral Comunicación, 2018
Este artículo analiza los debates que se produjeron en un sector de la intelectualidad de los Estados Unidos en torno a la relación entre los medios de comunicación y la sociedad, entre mediados de la década del cuarenta y principios de la del cincuenta.
Roberto Emiliano Sánchez Narvarte
doaj   +1 more source

Gut microbiota diversity is prognostic in metastatic hormone receptor‐positive breast cancer patients receiving chemotherapy and immunotherapy

open access: yesMolecular Oncology, EarlyView.
In this exploratory study, we investigated the relationship between the gut microbiota and outcome in patients with metastatic hormone receptor‐positive breast cancer, treated in a randomized clinical trial with chemotherapy alone or chemotherapy in combination with immune checkpoint blockade.
Andreas Ullern   +7 more
wiley   +1 more source

In vitro properties of patient serum predict clinical outcome after high dose rate brachytherapy of hepatocellular carcinoma

open access: yesMolecular Oncology, EarlyView.
Following high dose rate brachytherapy (HDR‐BT) for hepatocellular carcinoma (HCC), patients were classified as responders and nonresponders. Post‐therapy serum induced increased BrdU incorporation and Cyclin E expression of Huh7 and HepG2 cells in nonresponders, but decreased levels in responders.
Lukas Salvermoser   +14 more
wiley   +1 more source

Inhibition of CDK9 enhances AML cell death induced by combined venetoclax and azacitidine

open access: yesMolecular Oncology, EarlyView.
The CDK9 inhibitor AZD4573 downregulates c‐MYC and MCL‐1 to induce death of cytarabine (AraC)‐resistant AML cells. This enhances VEN + AZA‐induced cell death significantly more than any combination of two of the three drugs in AraC‐resistant AML cells.
Shuangshuang Wu   +18 more
wiley   +1 more source

The “Decolonizing” of Knowledge: A New Perspective on the Cape’s Storytelling (Review)

open access: yesУченые записки Института Африки Российской академии наук
Review of the book: Bam J. (2021). Ausi Told Me: Why Cape Herstoriographies Matter. Auckland Park: Jacana Media. 312 p.
Turianitsa Daria
doaj   +1 more source

Day Labor in San Rafael, California: The Feasibility of Uniting Contradictory Positions [PDF]

open access: yes, 2001
Feasibility Study done in 2001 for the City of San Rafael, CA, on organizing San Rafael's day laborers into a hiring ...

core  

A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression

open access: yesMolecular Oncology, EarlyView.
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak   +8 more
wiley   +1 more source

College of San Mateo Mathematics and Science Teacher Education Program: A Bay Area Collaborative for Excellence in Teacher Preparation with San Jose State University and San Francisco State University [PDF]

open access: yes, 1998
The College of San Mateo (CSM), a community college serving the San Mateo County area of California, is part of a collaborative effort in the San Francisco Bay Area to improve mathematics and science teacher preparation.
Tonini, C.
core   +1 more source

Adaptaquin is selectively toxic to glioma stem cells through disruption of iron and cholesterol metabolism

open access: yesMolecular Oncology, EarlyView.
Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié   +16 more
wiley   +1 more source

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