SARS‐CoV‐2 research using human pluripotent stem cells and organoids
Experimental cell models are indispensable for clarifying the pathophysiology of coronavirus disease 2019 (COVID‐19), which is caused by severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) infection, and for developing therapeutic agents.
Sayaka Deguchi +5 more
doaj +2 more sources
Cortical integrity changes with cognition, plasma biomarkers and APOE4 status across the adult healthy lifespan [PDF]
Abstract Background The relationship between cognitive age‐related changes and cortical macrostructural properties (i.e., cortical thickness [CTh]) has been extensively studied. However, less is known about the relation with microstructural characteristics (i.e., cortical mean diffusivity [cMD]) even though these are sensitive to preclinical phases of ...
Perera‐Cruz O +14 more
europepmc +4 more sources
Concurrent Biocompatibility and Antimicrobial Functionality of Soft Diamond-Like Carbon Coating for Healthcare Applications. [PDF]
Designing an engineering material that simultaneously promotes the growth of beneficial biological cells while eliminating harmful bacteria is often challenging. However, this study presents a unique carbon coating by manufacturing design capable of achieving both functions, demonstrating strong potential for various applications, including medical ...
Zia AW +8 more
europepmc +2 more sources
Mathematical Thinking and the VESS Model: A Descriptive Study
Critical, creative, and flexible thinking is one of the educational priorities in the 21st Century, at a time in which the world is showing its most ephemeral and uncertain side.
María Helena Romero-Esquinas +3 more
doaj +1 more source
Assessment of a Location-Based Mobile Augmented-Reality Game by Adult Users with the ARCS Model
In mobile augmented reality (MAR) games, learning by doing is important to supplement the theoretical knowledge with practical exercise in order to maximize the learning outcome. However, in many fields, the users are not able to apply their knowledge in
Konstantina Sdravopoulou +2 more
doaj +1 more source
Pharmacophore-Based Discovery of Viral RNA Conformational Modulators
New RNA-binding small-molecule scaffolds are needed to unleash the pharmacological potential of RNA targets. Here we have applied a pharmacophore-based virtual screening approach, seldom used in the RNA recognition field, to identify novel conformational
María Martín-Villamil +3 more
doaj +1 more source
Editorial: Ketogenic diets for cognitive and behavioral function [PDF]
Jose Enrique de la Rubia Ortí +4 more
doaj +2 more sources
Movens-Efficiens-Agens: la fundamentación causal en San Alberto Magno [PDF]
Molina, E. (Enrique)
core +2 more sources
Transformative Bioactive Wear Resistant Ti<sub>3</sub>Au:N and Ti<sub>3</sub>Au:O Coatings for Medical Implants and Devices. [PDF]
Coatings of titanium‐gold are grown in nitrogen and oxygen environments via magnetron sputtering to simultaneously enhance their biotribological and antibacterial properties. The coatings are highly crystalline with superhard scratch‐resistant surfaces and wear rates 20 times lower than the bare Ti‐6Al‐4V substrate.
Lukose CC +11 more
europepmc +2 more sources
The World Health Organization has called for new effective and affordable alternative antimicrobial materials for the prevention and treatment of microbial infections.
Isaías Sanmartín-Santos +5 more
doaj +1 more source

