Results 111 to 120 of about 482,619 (260)

Detecting Cognitive Decline and Dementia in Santa Cruz, Galápagos Islands, Ecuador. [PDF]

Cureus, 2020
Espinosa Del Pozo PH, Espinosa PS, Donadi E, Rogel L, Naranjo R, Haro GE, Riera DC, Mendoza GS, Garzón NA, Andrade NF.   +9 more
europepmc   +1 more source

Functional Suppression of SCAP Triggers Endoplasmic Reticulum Stress‐Dependent Ferroptosis by Impairing Cholesterol Metabolism in Gastric Cancer

Advanced Science, EarlyView.
This study reveals a novel GC therapy targeting cholesterol homeostasis. Inhibiting the SCAP sterol‐sensing domain causes lethal ER stress via cholesterol accumulation, paradoxically forcing continuous synthesis that triggers ferroptosis. The findings link sterol sensing, metabolic dysregulation, and ferroptosis, establishing an anti‐cancer paradigm ...
Qianqian Xu, Guangzhao Pan, Lele Zhang, Xiangliu Chen, Kui Zhang, Yang Lu, Zibo Duan, Aiping Chen, Hailong Shen, Yuxi Zhang, Xiaowu Dong, Jinzhou Huang, Xing Huang, Kai Miao, Qian Hua, Fangfang Tao, Weidong Zhang, Jiang‐Jiang Qin   +17 more
wiley   +1 more source

A PESCA REALIZADA NA COMUNIDADE DE PESCADORES ARTESANAIS DE SANTA CRUZ / ES - BRASIL

Boletim do Instituto de Pesca, 2018
Localizada no estuário do rio Piraquê-açu, Santa Cruz í  ES, uma comunidade de pescadores artesanais foi alvo de um estudo realizado durante os anos 2000 e 2001.
Ricardo NETTO, André NUNES, Jacqueline ALBINO   +2 more
doaj  

An Anterior Cingulate Cortex‐Anterior Insular Cortex Glutamatergic Circuit Gates Stress‐Induced Visceral Hypersensitivity and Anxiety via Ionotropic Glutamate Receptors Trafficking

Advanced Science, EarlyView.
This study identifies an anterior cingulate cortex (ACC) to anterior insular cortex (AIC) glutamatergic (Glu) circuit that gates stress induced visceral hypersensitivity and anxiety. Circuit activation induces both phenotypes, whereas inhibition relieves them.
Junwen Wang, Guangbing Duan, Huihui Sun, Zhiyu Dong, Qiwei Wang, Xiaowei Li, Ying Chen, Shuchang Xu, Ying Huang   +8 more
wiley   +1 more source

Palmitoylation of PSD‐95 Orchestrates Learning‐Dependent Metaplasticity in the Amygdala and Fear Memory

Advanced Science, EarlyView.
This study reveals that fear learning specifically triggers PICK1/DHHC2‐dependent palmitoylation of PSD‐95 in the lateral amygdala. Fear conditioning induces the dissociation of DHHC5 from PSD‐95 and the association of PSD‐95 with DHHC2. DHHC2‐mediated palmitoylation of PSD‐95 is required for synaptic transmission and underlies fear learning–induced ...
Zu‐Cheng Shen, Yu‐Xuan Weng, Zhi‐Xuan Xia, Yue‐Ling Zhao, Qian‐Qian Ding, Si‐Ying Wang, Ting Cao, Xuan‐Ying Chen, Wu‐Cheng Tao, Shen Lin, Zhou Chen, Yi‐Xiao Luo   +11 more
wiley   +1 more source

Microcerella (Diptera: Sarcophagidae) from Argentinean Patagonia: New records and new species Microcerella (Diptera: Sarcophagidae) para la Patagonia Argentina: Nuevos registros y nueva especie

Revista de la Sociedad Entomológica Argentina, 2004
Male of Microcerella lalie sp. nov. from Santa Cruz, Argentina is described and illustrated and new records from Austral Argentinean Patagonia are provided for Microcerella mallochi (Hall).Se describe e ilustra una nueva especie de Sarcophagidae ...
Juan C. Mariluis
doaj  

Matrix Stiffness Induces Endothelial Network Senescence

Advanced Science, EarlyView.
Using a 3D human in vitro model that decouples mechanical stress from inflammatory or biochemical signals, matrix stiffening induces a senescence phenotype in endothelial networks. This mechano‐induced senescence activates Notch signaling, and pharmacologic Notch inhibition attenuates this stiffness‐induced senescence.
Jiyeon Song, Alexandra N. Rindone, Ya Guan, Connor D. Amelung, Prarthana Sanjay Daswani, Jennifer H. Elisseeff, Sharon Gerecht   +6 more
wiley   +1 more source

Metal Concentrations in Sediments of the Alinsaog River, Santa Cruz, Zambales, Central Luzon, Philippines. [PDF]

J Health Pollut, 2020
Sazon RR, Migo VP.
europepmc   +1 more source

On Santa Cruz, por ejemplo(Santa Cruz, For Example)

Cultures & conflits, 2022
openaire   +1 more source

The E3 Ubiquitin Ligase RLIM Safeguards Oligodendrocyte Development and Myelination by Targeting SLC7A11 for Polyubiquitination to Regulate Ferroptotic Resistance

Advanced Science, EarlyView.
RLIM‐mediated SLC7A11 polyubiquitination is required for SPTBN2‐mediated trafficking and membrane localization of SLC7A11, which enables oligodendrocyte precursor cells to be resistant to ferroptosis and safeguards oligodendrocyte lineage progression and thus myelination.
Yuwei Li, Haijun Zhang, Jieya Zhou, Shiyu Yang, Jingmei Cha, Gaofeng Yan, Shuhua Zhao, Bingyu Mao, Pengcheng Ma   +8 more
wiley   +1 more source