Results 11 to 20 of about 8,508 (236)

Therapeutic approaches for SAPHO syndrome from the perspective of pathogenesis: a review of the literature [PDF]

Frontiers in Immunology
Synovitis, acne, pustulosis, hyperostosis and osteitis (SAPHO) syndrome is a rare autoinflammatory disease characterized by cutaneous manifestations and osteoarticular damage.
Yunuo Wang, Mengjiao Gu, Zixiang Zheng, Haixu Jiang, Luyao Han, Hanjing Huang, Yuanhao Wu, Chen Li, Chen Li   +8 more
doaj   +3 more sources

Awareness of the Risk of Paradoxical Psoriasis in Patients with SAPHO Syndrome Undergoing Treatment with Secukinumab: A Case Series [PDF]

Journal of Inflammation Research
Cheng Xu,* Xiayan Xu,* Yongmei Han Department of Rheumatology, Sir Run Run Shaw Hospital, Zhejiang University School of Medicine, Hangzhou, People’s Republic of China*These authors contributed equally to this workCorrespondence: Yongmei Han ...
Xu C, Xu X, Han Y
doaj   +3 more sources

JAK Inhibitors for Treatment of SAPHO Syndrome: A Systematic Review of 72 Cases. [PDF]

ACR Open Rheumatol
Synovitis, acne, pustulosis, hyperostosis, and osteitis (SAPHO) syndrome usually involves bones, joints, and skin. Due to a lack of known pathogenesis and clinical trials, there is no standard treatment of SAPHO syndrome.
Fazeli P, Bahramian S, Farahmand K, Ghoshouni H, Farahmand Y, Soheili A, Bagheri L, Memari H, Feyzi A, Vahabi SM.   +9 more
europepmc   +3 more sources

Secukinumab-induced paradoxical skin lesions,but successful treatment with tofacitinib in SAPHO syndrome: a case report

Journal of Dermatological Treatment, 2023
Synovitis, acne, pustulosis, hyperostosis, and osteitis (SAPHO) syndrome is a rare autoinflammatorydisorder without standardized therapy. IL-17 inhibitors have been effective in individual cases. However, some patients with SAPHO may develop psoriasiform
Li Luan, Chengzhi Lv
doaj   +2 more sources

Successful treatment of SAPHO syndrome with oral abrocitinib: a case report

Journal of Dermatological Treatment
Aim SAPHO (synovitis, acne, pustulosis, hyperostosis and osteitis) syndrome is a rare autoimmune disorder characterized by typical cutaneous lesions (palmoplantar pustulosis and eruptive acne) and osteoarticular symptoms (aseptic osteomyelitis and joint ...
Zhipeng Lin, Songyi Piao, Rongxin Zhang, Chao Yu, Zhao Hou, Aoxue Wang   +5 more
doaj   +2 more sources

Successful Treatment of Refractory Synovitis, Acne, Pustulosis, Hyperostosis, and Osteitis (SAPHO) Syndrome and Paradoxical Psoriasis with Secukinumab: A Case Report

Clinical, Cosmetic and Investigational Dermatology
Danyang Fan, Fuqiu Li, Zhe Liu, Zhanhan Tang, Sha Lv Department of Dermatology, The Second Hospital of Jilin University, Changchun, Jilin, 130000, People’s Republic of ChinaCorrespondence: Sha Lv, Department of Dermatology, The second hospital of Jilin ...
Fan D, Li F, Liu Z, Tang Z, Lv S
doaj   +2 more sources

New Insights in the Treatment of SAPHO Syndrome and Medication Recommendations

Journal of Inflammation Research, 2022
Wei Cheng, Fen Li, Jing Tian, Xi Xie, Jin-Wei Chen, Xiao-Fei Peng, Qi Tang, Yan Ge Department of Rheumatology and Immunology, The Second Xiangya Hospital, Central South University, Changsha, 410011, Hunan, People’s Republic of ChinaCorrespondence: Yan Ge,
Cheng W, Li F, Tian J, Xie X, Chen JW, Peng XF, Tang Q, Ge Y   +7 more
doaj   +2 more sources

Family aggregation and prevalence of other autoimmune diseases in SAPHO syndrome

Heliyon, 2023
Objective: SAPHO (Synovitis, Acne, Pustulosis, Hyperostosis and Osteitis) syndrome is a heterogeneous disease that clinically manifests as chronic inflammatory osteoarticular and dermatological lesions.
Chen Li, Hesong Wang, Haixu Jiang, Yuming Shao, Guangrui Huang, Kai Yuan, Shufeng Wei   +6 more
doaj   +1 more source

Genome-Wide Association Identifies Risk Pathways for SAPHO Syndrome

Frontiers in Cell and Developmental Biology, 2021
SAPHO syndrome is a rare chronic inflammatory disease which is characterized by the comprehensive manifestations of bone, joint, and skin. However, little is known about the pathogenesis of SAPHO syndrome.
Ruikun Cai, Ruikun Cai, Yichao Dong, Yichao Dong, Mingxia Fang, Mingxia Fang, Yuxuan Fan, Yuxuan Fan, Zian Cheng, Zian Cheng, Yue Zhou, Yue Zhou, Jianen Gao, Jianen Gao, Feifei Han, Changlong Guo, Changlong Guo, Xu Ma, Xu Ma   +18 more
doaj   +1 more source

Percutaneous vertebroplasty for SAPHO syndrome with vertebral destruction: a case report and literature review

Frontiers in Medicine, 2023
Synovitis, acne, pustulosis, hyperostosis and osteitis (SAPHO) syndrome is a rare musculoskeletal disease characterized by dermatological and osteoarticular lesions.
Yuanpei Cheng, Hao Feng, Junhan Mu, Jialin Chen, Han Wu   +4 more
doaj   +1 more source