Rewiring Steroidal Metabolic Pathways for Diosgenin Production in Solanum nigrum
ABSTRACT Diosgenin is a key starting material for the synthesis of steroidal drugs, such as corticosteroids and sex hormones. While the primary commercial source of diosgenin is the tubers of Dioscorea spp., identifying alternative plant hosts capable of diosgenin biosynthesis could enhance its production.
Jongbu Lim +16 more
wiley +1 more source
<i>Albizia amara</i>: A Potential Plant-Derived Surfactant for Cosmetic and Food Applications. [PDF]
Sadasivam Y, Pinfield VJ, Trybala A.
europepmc +1 more source
ABSTRACT Gynostemma pentaphyllum, a herb used in tea and traditional Chinese medicine, shows geographic variation in its production of valuable dammarane‐type ginsenosides and gypenoside LVI between populations from Suining (SN) and Nanning (NN). To elucidate the mechanisms underlying this differential metabolite accumulation, a chromosome‐level genome
Peina Zhou +12 more
wiley +1 more source
Correction: Integrated metabolome and transcriptome analysis identifies candidate genes involved in triterpenoid saponin biosynthesis in leaves of <i>Centella asiatica</i> (L.) Urban. [PDF]
Wan L +11 more
europepmc +1 more source
Multi‐Omics Insights Into Anthraquinone Biosynthesis in Rheum tanguticum
ABSTRACT Rheum tanguticum is renowned for its medicinal properties, including purgative, anti‐inflammatory and hepatoprotective effects, primarily attributed to anthraquinones (AQs). However, the molecular mechanisms of AQs biosynthesis have largely been hindered by insufficient genomic resources and functional genomics investigations.
Shuo Zhao +6 more
wiley +1 more source
Aryldiazonium-grafted bamboo-derived activated carbon: a solid acid catalyst with stable C-C bonded sulfonic acid sites for biodiesel production <i>via</i> esterification. [PDF]
Wang X, Zhang B, Hu Z, Zhao P, Wang Q.
europepmc +1 more source
ABSTRACT Understanding the impact of microbial interactions on plants is critical for maintaining healthy native ecosystems and sustainable agricultural practices. Despite the reality that genetically distinct plants host multiple microbes of large effect in the field, it remains unclear the extent to which host genotypes modulate non‐additive ...
Amanda H. Rawstern +3 more
wiley +1 more source
Optimization of ultrasound-assisted enzymatic extraction of saponins from Panax zingiberensis stems and leaves. [PDF]
Shen X +5 more
europepmc +1 more source
RAD51 and RAD51 paralog inhibition sensitizes nonreplicating quiescent keratinocytes to UV radiation
UV radiation and other compounds generate DNA adducts that block transcription and induce cell death if not removed by the nucleotide excision repair system. In this work, we used a small‐scale pharmacological screen to discover that inhibition of the recombinase RAD51 sensitized nonreplicating quiescent keratinocytes to both UVR and other agents that ...
Saman Khan +3 more
wiley +1 more source

