Gypenosides Damulin A and Damulin B Inhibit Hepatocellular Carcinoma by Regulating Cholesterol Synthesis. [PDF]
Drug Dev ResLi FF +6 more
europepmc +1 more source
Regulating Lipid Metabolism in Cancer: The Therapeutic Potential of Traditional Chinese Medicine
Phytotherapy Research, EarlyView.By regulating the reprogramming of lipid metabolism in tumor cells, TCM provides a novel strategy for antitumor therapy with reduced toxicity and enhanced efficacy. ABSTRACT Lipid metabolic reprogramming is a key feature of tumor cells to adapt to the microenvironment and plays an important role in tumor growth, invasion, and metastasis.
Yufeng Gao +11 more
wiley +1 more source
Applications and Action Mechanisms of <i>Yucca schidigera</i> Extract in Livestock, Poultry and Aquatic Animals. [PDF]
Animals (Basel)Xue S +7 more
europepmc +1 more source
Taste‐Active Peptides: Sensation Mechanisms and Structure–Taste Relationships
Sensory Neuroscience, EarlyView.Overview of taste‐active peptides, including taste bud cellular organization, peptide–receptor interactions and signaling pathways, structure–taste relationships, and integrated computational and experimental strategies for peptide discovery, mechanism elucidation, and flavor modulation.
Dengyi Pei +4 more
wiley +1 more source
High-Resolution Mass Spectrometry Reveals Distinct Temporal Accumulation Patterns of Metabolites in Reproductive Organs of Purple- and White-Flowered <i>Platycodon grandiflorus</i> Across Developmental Stages. [PDF]
Life (Basel)Lao J, Wang N, Yao C, Piao X.
europepmc +1 more source
Small, EarlyView.The study introduces a 3D sensing‐integrated platform enabling real‐time, non‐invasive monitoring of pH dynamics in patient‐derived PDAC tumorspheres. It revealed distinct extracellular acidification patterns under FOLFIRINOX, gemcitabine, and paclitaxel, correlating with therapeutic efficacy.
Stefania Forciniti +10 more
wiley +1 more source
On Modeling and Optimization for Separation, Concentration, and Purification of Saponins and Phenolic Compounds from Quinoa Hulls by Nanofiltration. [PDF]
Membranes (Basel)García López AI +5 more
europepmc +1 more source
Yeast, EarlyView.Harnessing Brazilian microbial diversity, comprehensive phenotypic screening of 79 yeast isolates identified non‐conventional strains with superior multi‐stress tolerance and metabolic versatility compared to S. cerevisiae under industrially relevant conditions.
Giovanna R. Maklouf +10 more
wiley +1 more source
Advances in Research on <i>Dioscorea nipponica</i> Makino: Chemical Constituents, Biological Activities and Developmental Prospects. [PDF]
MoleculesYuan L +7 more
europepmc +1 more source
Matrine–Tea Saponin Synergism Involves Suppressed Detoxification and Digestion in a Leaf Beetle
Integrative Zoology, EarlyView.Tea saponin and matrine showed synergistic toxicity against Plagiodera versicolora. Combined exposure suppressed digestion‐ and detoxification‐related processes, while silencing the trypsin gene Pver105950 and chitinase gene Pver001190 increased larval susceptibility to tea saponin and matrine, respectively.
Owais Khan +4 more
wiley +1 more source