Results 171 to 180 of about 72,403 (303)

Metabolic engineering reveals LUP5 as a determinant of saponin composition and insect feeding preference in Barbarea vulgaris. [PDF]

Plant Physiol
Shen J, Günther J, Kjeldgaard-Nintemann S, Cárdenas PD, Bak S.   +4 more
europepmc   +1 more source

Novel approaches for drug development against chronic primary pain: A systematic review

British Journal of Pharmacology, EarlyView.
Abstract Chronic primary pain (CPP) persisting for more than 3 months, associated with significant emotional distress without any known underlying cause, is an unmet medical need. Traditional or adjuvant analgesics do not provide satisfactory pain relief for a great proportion of these patients.
Valéria Tékus, Éva Borbély, Andreas Goebel, Ralf Baron, Zsófia Hajna, Zsuzsanna Helyes   +5 more
wiley   +1 more source

A comprehensive review on chemical structure, quality control, pharmacological effects, and structure-activity relationship of saponins from Zhuzishen (). [PDF]

J Tradit Chin Med
Zeting M, Qianqian XU, Mengqiong S, Wei G, Jihong Z, Maohua C, Jie XU, Huiquan HU, Gang Z, Haiming T.   +9 more
europepmc   +1 more source

Therapeutic potential of natural products in cancer immunotherapy: Advances and challenges

British Journal of Pharmacology, EarlyView.
This review systematically outlines the mechanisms underlying tumour immunotherapy resistance and elucidates the role of natural products in enhancing therapeutic efficacy as immunomodulatory adjuvants. Abstract Immunotherapy has emerged as a clinically pivotal approach in cancer treatment, but its application remains limited to a small subset of ...
Rao Hu, Kaibin Dai, Zhensheng Lin, Mingfang Ye, Minfeng Chen, Xiaobo Li, Dongmei Zhang   +6 more
wiley   +1 more source

Correction for Dervishi et al., Sterol divergence across eukaryotic kingdoms determines membrane susceptibility to saponins, a class of plant defense compounds. [PDF]

Proc Natl Acad Sci U S A
europepmc   +1 more source

Interfacial and Molecular Mechanisms of Pancreatic Lipase Modulation by Saponin-Rich Extracts with Antioxidant Activity. [PDF]

Molecules
Sroka Z, Kapusta K, Liyanage SD, Tobias T, Petrosyan V, Kolodziejczyk W, Imiełowska K, Gleńsk M, Żbikowska B, Gamian A, Wojciechowski K.   +10 more
europepmc   +1 more source

SAPONINS

Journal of Biological Chemistry, 1930
Walter A. Jacobs, Elmer E. Fleck
openaire   +1 more source

Notoginsenoside‐Fa mitigates vascular endothelial permeability via targeting SUGT1 to stabilize NLRP3 in a resting state

British Journal of Pharmacology, EarlyView.
Background and Purpose Notoginsenoside‐Fa (Noto‐Fa) is an emerging active compound derived from notoginseng with promise in treating cardiovascular diseases. The development of cardiovascular diseases is intricately linked to the damage of vascular endothelium and it is widely acknowledged that numerous chronic inflammation pathways, especially the ...
Xiao‐Ying Yu, Da‐Hao Mai, Xing‐Ming Zhong, Li‐Ting Huang, Lan‐Ting Fu, He‐Cai Wang, Ke Wang, Hai‐Yan Li, Qiu‐He Chen, Yang Chen   +9 more
wiley   +1 more source

Osteogenic Activity of New Dammarane-Type Saponins From Gynostemma pentaphyllum. [PDF]

Chem Biodivers
Duong NT, Ha TTT, Yen DTH, Thao DT, Tai BH, Van Kiem P.   +5 more
europepmc   +1 more source

Extracellular vesicles in pharmacology: Innovations in drug delivery and therapeutic applications in cancer

British Journal of Pharmacology, EarlyView.
Extracellular vesicles (EVs) are a diverse population of membrane nanoparticles secreted by nearly all cell types, playing a key role in intercellular communication by transferring bioactive macromolecular cargo. In cancer, EVs shape both the local tumour microenvironment and distant premetastatic niches.
Evangelia Pantazaka, Georgios Sivvas, Evangelia Papadimitriou, Constantinos M. Mikelis   +3 more
wiley   +1 more source