Results 231 to 240 of about 72,403 (303)

From Marginal to Central: Marginal Zone‐like B Cells as Critical Targets in Cladribine‐Treated Multiple Sclerosis

Annals of Neurology, Volume 100, Issue 4, Page 808-823, October 2026.
Objective Multiple sclerosis (MS) is a chronic autoimmune disease where B cells play a central pathogenic role. Cladribine, an oral therapy, provides durable benefits by reshaping lymphocyte populations, yet its specific long‐term impact on distinct B‐cell subsets is not fully understood.
Marta Pirronello, Mario Picozza, Gisella Guerrera, Silvia Corbisiero, Andrea Misiti, Roberta C. Placido, Alice Verdiani, Lorenzo de Marco, Manolo Sambucci, Elena Olivieri, Daniela F. Angelini, Esmeralda Quartuccio, Luca Prosperini, Carla Tortorella, Maria C. Buscarinu, Valeria Zancan, Francesca de Masi, Marco Salvetti, Claudio Gasperini, Giovanna Borsellino, Luca Battistini   +20 more
wiley   +1 more source

Chemical investigation of saponins from Medicago arborea

, 2004
DE BENEDETTO M. G, BIALY Z, MELLA M, AVATO, Pinarosa, ARGENTIERI, MARIA PIA, JURZYSTA M., TAVA A   +6 more
core  

Hyperacute Interleukin‐1β Production and Neutrophil Extracellular Trap Formation in the Cerebral Circulation of Stroke Patients with Large Vessel Occlusion

Annals of Neurology, Volume 100, Issue 4, Page 824-840, October 2026.
Acute ischemic stroke due to large vessel occlusion is associated with rapid intravascular immune activation. Analysis of arterial blood sampled distal to the thrombus during mechanical thrombectomy revealed increased extracellular adenosine triphosphate (ATP) and interleukin‐1β (IL‐1β) levels, evidence of inflammasome priming in monocytes, and ...
Justine Münsterberg, Caspar Brekenfeld, Hanna Englert, Marius Piepke, Regine J. Dress, Martin Oertel, Tina Fischer, Romy Hackbusch, Mingming Zha, Haodi Cai, Christian Casar, Ines S. Schädlich, Leo Winter, Alina Jander, Karoline Degenhardt, Maxim Bester, Fabian Flottmann, Uta Hanning, Brigitte Holst, Anna Worthman, Johanna Hiefner, Berenike Rutz, Eckhard Schlemm, Götz Thomalla, Bettina H. Clausen, Ann M. Stowe, Immo Prinz, Thiruma V. Arumugam, Markus Glatzel, Thomas Renné, Jens Fiehler, Eva Tolosa, Tim Magnus, Mathias Gelderblom   +33 more
wiley   +1 more source

Formulation, characterization, and efficacy evaluation of testolift: a novel testosterone-enhancing nutraceutical featuring synergistic black ginger methoxyflavones, fenugreek saponins, and zinc methionine <i>via</i> InSitu360 technology. [PDF]

RSC Adv
Amalraj A, Ramachandran Reshna K, Varma K, Jogy AM, Balakrishnan P, Gopi S.   +5 more
europepmc   +1 more source

SAPONINS

Journal of Biological Chemistry, 1925
openaire   +1 more source

Protective Effects of a Cissus quadrangularis Stem Peel Ash Derived Salt Against Streptozotocin Induced Cellular Injury in SH‐SY5Y Cells

Applied Research, Volume 5, Issue 5, October 2026.
Cissus quadrangularis stem peel‐derived bio salt protects SH‐SY5Y neuroblastoma cells against streptozotocin‐induced neurotoxicity by reducing oxidative stress, suppressing apoptosis, and improving cell viability. These findings highlight its potential as a natural neuroprotective agent for neurodegenerative disorders.
Panimalar Thirupathi Brindhavanam, Ramasamy Mahadevi, Veeran Sethuraman, Manickam Rajkumar, Kavitha Ramamoorthy   +4 more
wiley   +1 more source

Tandem Duplication-Driven Neofunctionalization of UDP-Glycosyltransferases Shapes the Diversification of Triterpenoid Saponins in the Cucurbitaceae. [PDF]

Adv Sci (Weinh)
Wang G, Li M, Dai X, Zhang Y, Wu Y, Yan Z, Tian C, Fan H, Liu H, Zhang X, Yang Y, Lu J, Sun Y, Wang Y.   +13 more
europepmc   +1 more source

Cytotoxic profiling of Hedera pastuchovii in human cancer cell lines and its genoprotective effects on normal lymphocytes. [PDF]

Sci Rep
Habibi E, Shokrzadeh M, Khojasteh OA, Gerey H, Hosseinzadeh MH, Sarker SD, Nahar L.   +6 more
europepmc   +1 more source

Integrated GNPS Molecular Networking and Network Pharmacology Uncover Methylophiopogonanone B as a Novel Anti-Inflammatory Agent From Polygonatum cyrtonema Hua Targeting the SRC-PI3K-Akt Pathway. [PDF]

Biomed Chromatogr
Han Y, Li R, Yao B, Hou X, Xu S, Yu L, Han J, Huang H, Cao D.   +8 more
europepmc   +1 more source

Biocatalytic structural diversification of saponins in Zygophyllum decumbens: HR-LC-ESI-TOF-MS/MS profiling and bioactivity modulation. [PDF]

BMC Complement Med Ther
Gabr NM, Abd-ElKhalik SM, Zaki JT, Abdel-Hafez LJM, El-Haddad AE.   +4 more
europepmc   +1 more source