Results 81 to 90 of about 82,209 (307)
British Journal of Clinical Pharmacology, EarlyView.Background Epidermal growth factor receptor–tyrosine kinase inhibitors (EGFR‐TKIs) have substantially improved outcomes in non‐small cell lung cancer (NSCLC); however, the development of treatment resistance remains a major clinical challenge. This study examines the association between concomitant prescriptions of H1‐antihistamines (H1AHs) and ...
Van Thuan Nguyen +10 more
wiley +1 more source
Stereoisomers of Saponins in Panax notoginseng (Sanqi): A Review
Frontiers in Pharmacology, 2018 Panax notoginseng (Sanqi), a traditional Chinese medical drug which has been applied to medical use for over four centuries, contains high content of dammarane-type tetracyclic triterpenoid saponins.
Ming Peng +6 more
doaj +1 more source
Lipase-catalyzed regioselective acylation of diosgenyl saponins
, 2001 Diosgenyl saponins were regio selectively acylated by Novozyme 435 with vinyl esters as acylating agents in THF to afford the corresponding mono- or diacyl diosgenyl saponins. (C) 2001 Elsevier Science Ltd.
Han, XW, Hui, YZ, Xing, GW, Yu, B
core
Biotechnology and Bioengineering, EarlyView.ABSTRACT Extracellular vesicles (EVs) are nanoscale membrane‐bound structures that play a pivotal role in intercellular communication by transporting bioactive molecules, including proteins, lipids, nucleic acids, and organelles, between cells. Originating from the endosomal pathway, EVs reflect the physiological and pathological status of their parent
Emine İncilay Torunoğlu +3 more
wiley +1 more source
Antiproliferative Oleanane Saponins from Dizygotheca elegantissima [PDF]
, 2012 Four new oleanane saponins (1-4), together with three known saponins, were isolated from the aerial parts of Dizygotheca elegantissima R. Vig. & Guillaumin. Their structures were elucidated by 1D and 2D NMR experiments including 1D TOCSY, DQF-COSY, HSQC,
N. Dekdouk Melle +12 more
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Furostanol and Spirostanol Saponins from Tribulus terrestris
, 2016 Twelve new steroidal saponins, including eleven furostanol saponins, terrestrinin J–T (1–11), and one spirostanol saponin, terrestrinin U (12), together with seven known steroidal saponins 13–19 were isolated from T. terrestris. The structures of the new
Xin-Bo Song +8 more
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Studies on Medicago lupulina saponins. 5. Isolation and chemical characterization of blossom saponins [PDF]
, 2014 The separation of saponins derived from Medicago lupulina L. flowers yielded two saponin fractions. The first one, made up of crystalline saponins, readily precipitable from water solution, was a mixture of three glycosides of soyasapogenol B.
Michał Płoszyński +4 more
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Saponins in Cancer Treatment: Current Progress and Future Prospects
, 2021 Saponins are steroidal or triterpenoid glycoside that is distinguished by the soap-forming nature. Different saponins have been characterized and purified and are gaining attention in cancer chemotherapy. Saponins possess high structural diversity, which
Opeyemi Iwaloye +3 more
core +1 more source
Tackling cancer stemness with nanotechnology in the era of precision medicine
BMEMat, EarlyView.Precise customization of nanoparticles (NPs) enables active targeting of cancer stem cells (CSCs), thereby improving drug delivery and therapeutic efficacy. NP‐based probing enhances CSC detection through imaging and liquid biopsy, whereas diverse therapeutic payloads improve therapeutic outcomes.
Shaolei Guo +9 more
wiley +1 more source
Isolation of two steroidal saponins with antileishmanial activity from Allium giganteum L.
Research in Pharmaceutical SciencesBackground and purpose: Alliums are rich sources of steroidal saponins, flavonoids, and sulphoric compounds of which steroidal saponins have recently received more attention due to their important pharmacological activities. Allium giganteum (giant onion)
Farnaz Chaparian +2 more
doaj +1 more source