Results 61 to 70 of about 106,902 (307)

Small Extracellular Vesicles from Neural Cells: Physiological and Pathological Roles, and Potential in Neurodegenerative Therapy

Advanced Healthcare Materials, EarlyView.
Neural cell–derived small extracellular vesicles (sEVs) are emerging as pivotal mediators in neurodegenerative diseases, exerting both pathogenic and therapeutic functions. This review synthesizes current evidence on how sEVs from distinct neural cell types regulate neurodegeneration, neuroprotection, biomarker discovery, and targeted drug delivery ...
Muhammad Waqas Salim, Wei Zhang, Lyndsey Collins‐Praino, Yuling Wang, Andrew Care   +4 more
wiley   +1 more source

Enhanced initiation of somatic embryos in suspension cultures of Aesculus flava and metabolic profile of zygotic embryos and somatic embryos during their development

Frontiers in Plant Science
Zygotic embryos (ZEs) of Aesculus species contain a plethora of health-promoting phytochemicals that are used in the pharmaceutical industry and traditional medicine.
Snežana Zdravković-Korać, Uroš Gašić, Slađana Jevremović, Branka Uzelac, Maja Belić, Dušica Ćalić, Jelena Milojević   +6 more
doaj   +1 more source

Poecillastrosides, Steroidal Saponins from the Mediterranean Deep-Sea Sponge Poecillastra compressa (Bowerbank, 1866)

Marine Drugs, 2017
The first chemical investigation of the Mediterranean deep-sea sponge Poecillastra compressa (Bowerbank, 1866) led to the identification of seven new steroidal saponins named poecillastrosides A–G (1–7).
Kevin Calabro, Elaheh Lotfi Kalahroodi, Daniel Rodrigues, Caridad Díaz, Mercedes de la Cruz, Bastien Cautain, Rémi Laville, Fernando Reyes, Thierry Pérez, Bassam Soussi, Olivier P. Thomas   +10 more
doaj   +1 more source

Endocytic Control of Cell‐Autonomous and Non‐Cell‐Autonomous Functions of p53

Advanced Science, EarlyView.
NUMB Ex3‐containing isoforms localize to the plasma membrane, where they recruit p53 through SNX9 and direct it to multivesicular bodies and exosomes. Exported p53 is taken up by neighboring cells and activates nuclear programs, revealing an intercellular, exosome‐based pathway that might help establish a tumor‐suppressive microenvironment.
Roberta Cacciatore, Andrea Basile, Stefano Freddi, Irene Schiano Lomoriello, Carlo Ribelle Zucca, Giuseppe Ciossani, Luigi Scietti, Alessandro Cuomo, Simona Ronzoni, Simone Pelicci, Mario Faretta, Elena Zaccheroni, Giuliana Pelicci, Vittoria Matafora, Angela Bachi, Rosalind Helen Gunby, Salvatore Pece, Sara Sigismund, Letizia Lanzetti, Ivan Nicola Colaluca, Pier Paolo Di Fiore   +20 more
wiley   +1 more source

Antitumor activity of Bulgarian herb Tribulus terrestris L. on human breast cancer cells [PDF]

Journal of BioScience and Biotechnology, 2013
Medicinal plants have been intensively studied as a source of antitumor compounds. Due to the beneficial climate conditions Bulgarian herbs have high pharmacological potential.
Svetla Angelova, Zlatina Gospodinova, Maria Krasteva, Georgi Antov, Valentin Lozanov, Tsanko Markov, Stefan Bozhanov, Elena Georgieva, Vanio Mitev   +8 more
doaj  

Preliminary qualitative screening for cancer chemopreventive agents in Telfairia occidentalis Hook.f., Gnetum africanum Welw., Gongronema latifolium Benth. and Ocimum gratissimum L. from Nigeria [PDF]

, 2009
The leaves of four plant foods commonly consumed in Nigeria namely Gnetum africanum (Igbo name: Ukazi), Gongronema latifolium (Igbo name: Utazi), Telfairia occidentalis (Igbo name: Ugu), Ocimum gratissimum (Igbo name: Nchoanwu), were each screened for ...
Iweala, E. E. J.
core  

Integration of Spatiotemporal Multi‐Omics in Peach Fruit Unravels a Metabolic Niche and the Genetic Basis of Trichome‐Mediated Stress Adaptation

Advanced Science, EarlyView.
This study constructed the first spatiotemporal multi‐omics map of peach fruit and discovered a key candidate gene that synergistically regulates trichome development and drought tolerance through the jasmonic acid signaling pathway, providing insights into the coupling mechanism between development and stress resistance.
Zhixin Liu, Ke Cao, Liping Guan, Aizhi Qin, Yong Li, Zihao Zhao, Yinpeng Zhang, Yaping Zhou, Lirong Wang, Xuwu Sun   +9 more
wiley   +1 more source

Cadmium and Copper Stress Responses in Soapbark Tree (Quillaja saponaria): Effects on Growth, Metal Accumulation, Saponin Concentration, and Gene Expression

Plants
Heavy metals such as Cu and Cd are important pollutants. Quillay (Quillaja saponaria) is a tree species endemic to Chile that is of worldwide commercial interest due to its saponins. It can grow on contaminated sites.
Javiera Lazo, Jaime Tapia, Fernando P. Guerra   +2 more
doaj   +1 more source

Formulation of Liquorice Root Extract (Glycyrrhiza Glabra L.) as Skin Whitening Cream [PDF]

, 2016
Liquorice root extract (Glycyrrhiza glabra L.) contains glabridin, an isoflavane as inhibitors of tyrosinase. This enzyme is responsible in melanin synthesis.
Faridah, F. (Faridah), Michico, M. (Michico), Noor, S. U. (Siti)   +2 more
core   +1 more source

Dual‐Physical‐Field Nanocatalysis: Injectable Hydrogel Enables Piezo‐Photothermal Synergy for Breast Cancer Therapy

Advanced Science, EarlyView.
ABSTRACT Piezocatalytic therapy (PCT) harnesses mechanical energy to generate tumor‐lethal reactive oxygen species (ROS), but its efficacy is limited by rapid electron‐hole recombination and poor intratumoral retention. To overcome these limitations, we engineered heterostructured BiOCl@CuO nanosheets embedded in an injectable, conductive ...
Can Tian, Shihan Xiao, Xuan Chen, Danni Zhang, Zizhen Liu, Jing Wang, Ning Xie, Wei Li   +7 more
wiley   +1 more source