Results 41 to 50 of about 72,403 (303)

Extraction and Analysis of Six Effective Components in Glycyrrhiza uralensis Fisch by Deep Eutectic Solvents (DES) Combined with Quantitative Analysis of Multi-Components by Single Marker (QAMS) Method

Molecules, 2021
Deep eutectic solvents (DESs) are green organic solvents that have broad prospects in the extraction of effective components of traditional Chinese medicine.
Ping Yu, Qian Li, Yanmei Feng, Sinan Ma, Yuying Chen, Guichen Li   +5 more
doaj   +1 more source

Endogenous resistance to insect pests in alfalfa: engineering for enhanced resistance [PDF]

, 1997
Alfalfa (Medicago sativa) is a valuable forage crop grown throughout the World. While the crop is resistant to attack by many insect pests, it is subject to potentially severe losses through the action of several specific pests, which are adapted to ...
Mazahery-Laghab, Hojjatollah, Mazahery-Laghab, H.   +1 more
core  

Hydrophilic interaction chromatography for selective separation of isomeric saponins

, 2014
A method based on a Click Xlon zwitterionic stationary phase was developed to separate isomeric saponins efficiently in hydrophilic interaction chromatography (HILIC) mode using methanol as a weak eluent. The retention times of a set of isomeric saponins,
Liang, Xinmiao, Guo, Xiujie, Zhang, Xiuli, Guo, Zhimou, Shen, Aijin, Liu, Yanfang, Jin, Gaowa, 张秀莉   +7 more
core   +1 more source

Membrane‐Active Peptide Protects Against Inflammation by Targeting NLRP3 Activation at the Trans‐Golgi Network

Advanced Science, EarlyView.
The membrane‐active peptide Pep19‐2.5 reduces harmful inflammation by blocking activation of the NLRP3 inflammasome at trans‐Golgi network membranes. By targeting key membrane interactions, Pep19‐2.5 suppresses inflammatory IL‐1β production and alleviates allergic airway inflammation in mice, leading to reduced immune cell infiltration and improved ...
Jonas Engelhardt, Nico Kirsch, Aileen Kerfin, Lars P. Lunding, Dominic Ferber, Hannes Buthmann, Ilka Schreier, Carlotta Bosio, Ann‐Kathrin Dobbelstein, Anna Klawonn, Rebecca C. Coll, Lena Bauernhofer, Sandro Keller, Matthias Geyer, Michael Wegmann, Andra B. Schromm, Günther Weindl   +16 more
wiley   +1 more source

Antihyaluronidase and Antioxidant Potential of Atriplex sagittata Borkh. in Relation to Phenolic Compounds and Triterpene Saponins

Molecules, 2023
The genus Atriplex provides species that are used as food and natural remedies. In this work, the levels of soluble phenolic acids (free and conjugated) and flavonoids in extracts from roots, stems, leaves and flowers of the unexplored Atriplex sagittata
Karolina Grabowska, Wioleta Pietrzak, Paweł Paśko, Agnieszka Sołtys, Agnieszka Galanty, Paweł Żmudzki, Renata Nowak, Irma Podolak   +7 more
doaj   +1 more source

ATL2 Recruits TRAK1 to Promote Mitochondrial Transport at ER–Mitochondria Contact Sites

Advanced Science, EarlyView.
ABSTRACT Mitochondrial transport and distribution are crucial for cellular homeostasis, yet whether and how they are regulated by endoplasmic reticulum (ER)–mitochondria contact sites remains unclear. Here, we demonstrate that the ER protein atlastin‐2 (ATL2) orchestrates mitochondrial transport and distribution by promoting assembly of the transport ...
Yiru Cheng, Peiyuan Chai, Xiayuhe Pei, Yiwen Chen, Xiaoshuai Huang, Bei Liu, Yiqian Wu, Junlin Teng, Pengli Zheng, Jianguo Chen   +9 more
wiley   +1 more source

Fotossensibilização hepatógena em eqüinos pela ingestão de Brachiaria humidicola (Gramineae) no Estado do Pará Hepatogenous photosensitization in horses caused by Brachiaria humidicola (Gramineae) in the State of Pará

Pesquisa Veterinária Brasileira, 2006
São apresentados os aspectos clínico-patológicos e epidemiológicos de doença, caracterizada por fotossensibili-zação, que ocorre em eqüinos no nordeste do Estado do Pará.
José Diomedes Barbosa, Carlos Magno C. de Oliveira, Carlos Hubinger Tokarnia, Paulo Vargas Peixoto   +3 more
doaj   +1 more source

Serjanic Acid Glycosides from Chenopodium hybridum L. with Good Cytotoxicity and Selectivity Profile against Several Panels of Human Cancer Cell Lines

Molecules, 2021
Two triterpene saponins, including a novel serjanic acid derivative, were isolated from Chenopodium hybridum L. (Amaranthaceae) aerial parts. Their structures were elucidated by a combination of spectroscopic methods (MS, 1D and 2D NMR).
Karolina Grabowska, Łukasz Pecio, Agnieszka Galanty, Paweł Żmudzki, Wiesław Oleszek, Irma Podolak   +5 more
doaj   +1 more source

Engineered Brain‐Targeted Exosomes Delivering FGF1 for Sustained Glycemic Regulation and Multitarget Neurovascular Protection in Diabetic Stroke

Advanced Science, EarlyView.
ABSTRACT Diabetic stroke is characterized by a hyperglycemic and pro‐inflammatory microenvironment that exacerbates neurovascular dysfunction. However, the blood–brain barrier (BBB) remains a formidable obstacle, restricting the delivery of most therapeutic molecules.
Bixin Shen, Chengxiang Zhang, Junhui Wang, Xichong Zhong, Shihao Chen, Xue Wang, Xiaokun Li, Li Lin   +7 more
wiley   +1 more source

Tissue-Specific Accumulation of Sulfur Compounds and Saponins in Different Parts of Garlic Cloves from Purple and White Ecotypes

Molecules, 2017
This study set out to determine the distribution of sulfur compounds and saponin metabolites in different parts of garlic cloves. Three fractions from purple and white garlic ecotypes were obtained: the tunic (SS), internal (IS) and external (ES) parts ...
Gianfranco Diretto, Angela Rubio-Moraga, Javier Argandoña, Purificación Castillo, Lourdes Gómez-Gómez, Oussama Ahrazem   +5 more
doaj   +1 more source