Results 121 to 130 of about 6,013 (134)
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Clinical Therapeutics, 2010
Phenylketonuria (PKU) is an autosomal recessive metabolic disorder characterized by hyperphenylalaninemia in association with neurocognitive and neuromotor impairment. Sapropterin dihydrochloride (hereafter referred to as sapropterin) administered orally as dissolved tablets is approved by the US Food and Drug Administration for hyperphenylalaninemia ...
Donald G, Musson +6 more
exaly +3 more sources
Phenylketonuria (PKU) is an autosomal recessive metabolic disorder characterized by hyperphenylalaninemia in association with neurocognitive and neuromotor impairment. Sapropterin dihydrochloride (hereafter referred to as sapropterin) administered orally as dissolved tablets is approved by the US Food and Drug Administration for hyperphenylalaninemia ...
Donald G, Musson +6 more
exaly +3 more sources
Expert Opinion on Investigational Drugs, 2008
Sapropterin dihydrochloride, 6-R-L-erythro-5,6,7,8-tetrahydrobiopterin (BH4) is being introduced in the US for treatment of phenylketonuria (PKU). This compound has been in use in Europe to treat mild forms of PKU. Tetrahydrobiopterin is the cofactor in the hydroxylation reaction of the three aromatic amino acids phenylalanine, tyrosine and tryptophan.
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Sapropterin dihydrochloride, 6-R-L-erythro-5,6,7,8-tetrahydrobiopterin (BH4) is being introduced in the US for treatment of phenylketonuria (PKU). This compound has been in use in Europe to treat mild forms of PKU. Tetrahydrobiopterin is the cofactor in the hydroxylation reaction of the three aromatic amino acids phenylalanine, tyrosine and tryptophan.
openaire +2 more sources
Sapropterin Dihydrochloride < Prop INNM >
Drugs of the Future, 1991J. Prous, J. Castañer
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Determination of Sapropterin Dihydrochloride in Solid Dosage form by Visible Spectrophotometry
Asian Journal of Pharmaceutical Analysis, 2017U. Viplava Prasad +2 more
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New Drugs: Nebivolol hydrochloride, nilotinib, and sapropterin dihydrochloride
Journal of the American Pharmacists Association, 2008openaire +2 more sources
IDrugs : the investigational drugs journal, 2008
Phenylketonuria (PKU) and mild hyperphenylalaninemia (HPA) are genetic disorders characterized by a deficiency in phenylalanine hydroxylase (PAH), resulting in intellectual impairment if not treated with dietary restriction of phenylalanine intake.
openaire +1 more source
Phenylketonuria (PKU) and mild hyperphenylalaninemia (HPA) are genetic disorders characterized by a deficiency in phenylalanine hydroxylase (PAH), resulting in intellectual impairment if not treated with dietary restriction of phenylalanine intake.
openaire +1 more source
Partial Hydatidiform Mole in a Phenylketonuria Patient Treated With Sapropterin Dihydrochloride
Gynecological Endocrinology, 2017Hatice Serap Sivri +2 more
exaly