Results 31 to 40 of about 2,350 (180)
Advanced Science, EarlyView.Antibody–drug conjugates (ADCs) transform breast cancer therapy, yet resistance limits their durability. Emerging evidence reveals that ADC failure is not solely tumor‐intrinsic but shaped by dynamic tumor–microenvironment interactions that alter drug delivery, processing, and response.
Minji Seo, Jangsoon Lee, Naoto T. Ueno
wiley +1 more source
SAR-Assisted Energy-Efficient Hybrid ADCs
IEEE Open Journal of the Solid-State Circuits SocietyThe distinct advantages of low power consumption and hardware compactness make SAR ADCs especially appealing in scaled CMOS technologies, garnering significant attention.
Kent Edrian Lozada +4 more
doaj +1 more source
IET Circuits, Devices and Systems, 2021 A novel switched‐capacitor integrator based programmable resolution analog to digital converter (ADC) architecture is proposed. The proposed hybrid ADC architecture can be switched between successive approximation register (SAR) and delta‐sigma modulator
Sreenivasulu Polineni +2 more
doaj +1 more source
GPCRs in CAR‐T Cell Immunotherapy: Expanding the Target Landscape and Enhancing Therapeutic Efficacy
Advanced Science, EarlyView.Chimeric antigen receptor T cell therapy faces dual challenges of target scarcity and an immunosuppressive microenvironment in solid tumors. This review highlights how G protein‐coupled receptors can serve as both novel targets to expand the therapeutic scope and functional modules to enhance CAR‐T cell efficacy.
Zhuoqun Liu +11 more
wiley +1 more source
A Biomedical Sensor System With Stochastic A/D Conversion and Error Correction by Machine Learning
IEEE Access, 2019 This paper presents a high-precision biomedical sensor system with a novel analog-frontend (AFE) IC and error correction by machine learning. The AFE IC embeds an analog-to-digital converter (ADC) architecture called successive stochastic approximation ...
Yusaku Hirai +6 more
doaj +1 more source
Advanced Science, EarlyView.ABSTRACT Current prostate cancer detection methods remain limited in non‐invasiveness and specificity, prompting interest in urinary biomarkers such as sarcosine. Here, we report a urine‐powered wearable platform for non‐invasive sarcosine detection as a proof‐of‐concept for decentralized early warning.
Jing Xu +10 more
wiley +1 more source
IEEE AccessThis paper presents a cost-effective compact 5-bit successive approximation register (SAR) analog-to-digital converter (ADC) for state-of-the-art computing processor and memory applications.
Chan-Keun Kwon, Young-Jae Min
doaj +1 more source
Electronics Letters, 2023 This letter presents an 11 b 200 MS/s 28 nm CMOS 2b/cycle successive‐approximation register (SAR) analogue‐to‐digital converter (ADC). The offset calibration technique is proposed to reduce the comparator offset mismatch that degrades the linearity of ...
Jaehyuk Lee +9 more
doaj +1 more source
Fabrication of High‐Density Multimodal Neural Probes Based on Heterogeneously Integrated CMOS
Advanced Science, EarlyView.A chiplet‐based methodology democratizes active neural probe development on standard bulk CMOS services. This yields the first probe combining high‐density electrophysiology (416 electrodes) with calcium imaging (832 photodiodes) and complete on‐chip signal processing across 13 shanks.
Ju Hee Mun +10 more
wiley +1 more source
RRAM Variability Harvesting for CIM‐Integrated TRNG
Advanced Electronic Materials, EarlyView.This work demonstrates a compute‐in‐memory‐compatible true random number generator that harvests intrinsic cycle‐to‐cycle variability from a 1T1R RRAM array. Parallel entropy extraction enables high‐throughput bit generation without dedicated circuits. This approach achieves NIST‐compliant randomness and low per‐bit energy, offering a scalable hardware
Ankit Bende +4 more
wiley +1 more source