Results 51 to 60 of about 136,043 (299)

TNF Inhibitor-Induced Sarcoidosis-Like Lesions in Inflammatory Bowel Disease. [PDF]

United European Gastroenterol J
ABSTRACT Background While tumor necrosis factor (TNF) inhibitors can induce paradoxical reactions, sarcoidosis‐like disease has hardly been reported so far. This study aimed to describe the epidemiological, diagnostic and therapeutic features of TNF inhibitor‐induced sarcoidosis‐like lesions in patients with inflammatory bowel disease.
Chkolnaia Z, Lebrun-Vignes B, Amiot A, Uzzan M, Richard N, Charkaoui M, Le Cosquer G, Stefanescu C, Serrero M, Plastaras L, Vieujean S, Laharie D, Seksik P.   +12 more
europepmc   +2 more sources

Hepatosplenic sarcoidosis complicated by liver cirrhosis [PDF]

, 2015
Sarcoidosis is a multisystemic disease usually affecting the lungs and mediastinal lymph nodes. Other organs, such as the liver and the spleen, are less commonly involved. Patients usually present with mild nonspecific symptoms.
Bernard, Philippe, Peters, Benjamin, Van Dijck, Herwig, Van Overbeke, Lode, Vanhoenacker, Filip   +4 more
core   +3 more sources

A 73‐Year‐Old Man With Several Years of Difficulty Climbing Stairs and Frequent Tripping

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT A 73‐year‐old man presented with progressive weakness and atrophy predominantly affecting the distal finger flexors and quadriceps muscles. Electrophysiological studies demonstrated mixed myogenic and neurogenic features. Muscle MRI showed inflammatory changes, and muscle biopsy revealed granulomatous myositis with histologic features ...
Mehmet Can Sari, Arens Taga, Sonya Ulrike Steele, Ahmet Hoke   +3 more
wiley   +1 more source

Development of a T7 Phage Display Library to Detect Sarcoidosis and Tuberculosis by a Panel of Novel Antigens

EBioMedicine, 2015
Sarcoidosis is a granulomatous inflammatory disease, diagnosed through tissue biopsy of involved organs in the absence of other causes such as tuberculosis (TB).
Harvinder Talwar, Rita Rosati, Jia Li, Dana Kissner, Samiran Ghosh, Félix Fernández-Madrid, Lobelia Samavati   +6 more
doaj   +1 more source

Transcriptome Analysis of Peripheral Blood Mononuclear Cells in Pulmonary Sarcoidosis

Frontiers in Medicine, 2022
BackgroundSarcoidosis is a granulomatous systemic disease of unknown etiology. Mononuclear cells such as macrophages or lymphocytes in lung tissue and hilar or mediastinal lymph nodes have been recognized to play an essential role in granuloma formation ...
Keiichiro Yoshioka, Hironori Sato, Hironori Sato, Takeshi Kawasaki, Daisuke Ishii, Takuro Imamoto, Mitsuhiro Abe, Yoshinori Hasegawa, Osamu Ohara, Koichiro Tatsumi, Takuji Suzuki   +10 more
doaj   +1 more source

Ipilimumab, not just another anti-cancer therapy: hypophysitis as side effect illustrated by four case-reports [PDF]

, 2014
Ipilimumab is a monoclonal antibody that blocks cytotoxic T-lymphocyte antigen4 (CTLA-4), an inhibitory molecule typically expressed on T cells. Blockade of CTLA-4 induces an overall activation of T cells, including an immune-mediated anti-tumour ...
Brochez, Lieve, Cocquyt, Veronique, KRUSE, VIBEKE, Marlier, Joke, Van Belle, Simon   +4 more
core   +2 more sources

Clinical Practice Guideline for Evaluation and Management of Peripheral Nervous System Manifestations in Sjögren's Disease

Arthritis Care &Research, Accepted Article.
Objectives Sjögren's disease is an autoimmune disorder that can impact multiple organ systems, including the peripheral nervous system (PNS). PNS manifestations, which can exist concurrently, include mononeuropathies, polyneuropathies, and autonomic nervous system neuropathies. To help patients and providers in the decision‐making process, we developed
Anahita Deboo, Robert Fox, Katherine M. Hammitt, Julie Frantsve‐Hawley, Matthew C. Baker, Stamatina Danielides, Eduardo De Sousa, Brent P. Goodman, Jennifer K. King, Steven Mandel, Ghaith Noaiseh, Pantelis P. Pavlakis, George Sarka, R. Hal Scofield, Arun Varadhachary, Daniel J. Wallace, Matt Makara, Nancy Carteron, Steven Carsons, In collaboration with the Consensus Expert Panel (CEP) members   +19 more
wiley   +1 more source

[Sarcoidosis]. [PDF]

Pathologica, 1996
SummarySarcoidosis is a multisystem granulomatous disorder of unknown aetiology. The condition commonly affects young adults and frequently presents with bilateral hilar lymphadenopathy with or without pulmonary infiltration, ocular or cutaneous lesions. The clinical presentation can be extremely varied depending upon the organs affected. The diagnosis
CHILOSI, Marco, MENESTRINA, Fabio
openaire   +5 more sources

Gastric Sarcoidosis: A Rare Clinical Presentation

Case Reports in Gastrointestinal Medicine, 2013
Gastrointestinal (GI) sarcoidosis is a very rare disease, which clinically presents along with systemic disease or as an isolated finding. Gastric sarcoidosis is the most common form of GI sarcoidosis. Symptomatic gastric sarcoidosis is rare and only few
Hemasri Tokala, Karthik Polsani, Jagadeesh K. Kalavakunta   +2 more
doaj   +1 more source

Active chronic sarcoidosis is characterized by increased transitional blood B cells, increased IL-10-producing regulatory B cells and high BAFF levels.

PLoS ONE, 2012
BackgroundSarcoidosis is a multisystemic disease of unknown etiology characterized by a disproportionate Th1 granulomatous immune response in the organs involved.
Anne Saussine, Abdellatif Tazi, Séverine Feuillet, Michel Rybojad, Caroline Juillard, Anne Bergeron, Valérie Dessirier, Fatiha Bouhidel, Anne Janin, Armand Bensussan, Martine Bagot, Jean-David Bouaziz   +11 more
doaj   +1 more source