Results 51 to 60 of about 122,915 (293)

Transcriptome Analysis of Peripheral Blood Mononuclear Cells in Pulmonary Sarcoidosis

Frontiers in Medicine, 2022
BackgroundSarcoidosis is a granulomatous systemic disease of unknown etiology. Mononuclear cells such as macrophages or lymphocytes in lung tissue and hilar or mediastinal lymph nodes have been recognized to play an essential role in granuloma formation ...
Keiichiro Yoshioka, Hironori Sato, Hironori Sato, Takeshi Kawasaki, Daisuke Ishii, Takuro Imamoto, Mitsuhiro Abe, Yoshinori Hasegawa, Osamu Ohara, Koichiro Tatsumi, Takuji Suzuki   +10 more
doaj   +1 more source

Sarcoidosis as an Autoimmune Disease

Frontiers in Immunology, 2020
Despite the large number of performed studies, the etiology and pathogenesis of sarcoidosis still remain unknown. Most researchers allude to the possible autoimmune or immune-mediated genesis of the disease.
A. Starshinova, A. Malkova, N. Basantsova, Y. Zinchenko, I. Kudryavtsev, G. A. Ershov, L. Soprun, Vera A. Mayevskaya, L. Churilov, P. Yablonskiy   +9 more
semanticscholar   +1 more source

Nondiagnostic, radial‐probe endobronchial ultrasound‐guided biopsy for peripheral lung lesions: The added value of radiomics from ultrasound imaging for predicting malignancy

Thoracic Cancer, Volume 14, Issue 2, Page 177-185, January 2023., 2023
This study investigated whether radiomic features extracted from radial‐probe endobronchial ultrasound (radial EBUS) images can assist in decision‐making for subsequent clinical management in cases with indeterminate pathologic results. We demonstrated a radiomics‐added, malignancy prediction model that can categorize lesions with nondiagnostic lung ...
Jihwan Choi, Sungmin Zo, Jong Hoon Kim, You Jin Oh, Joong Hyun Ahn, Myoungkyoung Kim, Kyungjong Lee, Ho Yun Lee   +7 more
wiley   +1 more source

Gastric Sarcoidosis: A Rare Clinical Presentation

Case Reports in Gastrointestinal Medicine, 2013
Gastrointestinal (GI) sarcoidosis is a very rare disease, which clinically presents along with systemic disease or as an isolated finding. Gastric sarcoidosis is the most common form of GI sarcoidosis. Symptomatic gastric sarcoidosis is rare and only few
Hemasri Tokala, Karthik Polsani, Jagadeesh K. Kalavakunta   +2 more
doaj   +1 more source

Identification of Jak-STAT signaling involvement in sarcoidosis severity via a novel microRNA-regulated peripheral blood mononuclear cell gene signature

Scientific Reports, 2017
Sarcoidosis is a granulomatous lung disorder of unknown cause. The majority of individuals with sarcoidosis spontaneously achieve full remission (uncomplicated sarcoidosis), however, ~20% of sarcoidosis-affected individuals experience progressive lung ...
Tong Zhou, Nancy Casanova, Nima Pouladi, Ting Wang, Yves Lussier, Kenneth S. Knox, Joe G. N. Garcia   +6 more
doaj   +1 more source

A Rare Case of Systemic Sarcoidosis in a Middle-Aged Female with a Solitary Thyroid Nodule

Case Reports in Endocrinology, 2021
Sarcoidosis is a multisystem inflammatory disease characterized by the presence of noncaseating granulomas. Sarcoidosis can affect any organ of the body, the lung being the most affected. Sarcoidosis rarely affects the thyroid gland, and only a few cases
Ayrton Bangolo, John Bukasa Kakamba, Ali Atoot, Mohammad Jurri, Ashraf Mahmoud, Arthur Oliver Lo, Kunchang Song, Syed Sirajuddin, Adam Atoot   +8 more
doaj   +1 more source

Epidemiology of sarcoidosis: current findings and future directions

Therapeutic Advances in Chronic Disease, 2018
Sarcoidosis is a granulomatous inflammatory disease with unknown etiology. Epidemiological studies have contributed greatly to our knowledge about sarcoidosis, providing critical information on the determinants and distribution of the disease.
Elizabeth V. Arkema, Y. Cozier
semanticscholar   +1 more source

Silicosarcoidosis: Histologic and Clinical Features of an Occupational Granulomatous Disease

American Journal of Industrial Medicine, EarlyView.
ABSTRACT Sarcoidosis is a multisystem inflammatory disease of unknown etiology. Growing evidence indicates that occupational exposure to respirable crystalline silica (RCS) is associated with an increased incidence of sarcoidosis. Yet a diagnosis of sarcoidosis rarely prompts investigation to identify preventable exposures.
Jeremy T. Hua, Carlyne D. Cool, Einat Fireman Klein, Yochai Adir, Lukas J. Lee, Lauren M. Zell‐Baran, Robert A. Cohen, Richard C. Kraus, E. Brigitte Gottschall, Silpa D. Krefft, Charles Van Hook, Cecile S. Rose   +11 more
wiley   +1 more source

Development of a T7 Phage Display Library to Detect Sarcoidosis and Tuberculosis by a Panel of Novel Antigens

EBioMedicine, 2015
Sarcoidosis is a granulomatous inflammatory disease, diagnosed through tissue biopsy of involved organs in the absence of other causes such as tuberculosis (TB).
Harvinder Talwar, Rita Rosati, Jia Li, Dana Kissner, Samiran Ghosh, Félix Fernández-Madrid, Lobelia Samavati   +6 more
doaj   +1 more source

Treatment of Multiorgan Sarcoidosis With Tofacitinib

ACR Open Rheumatology, 2020
Sarcoidosis is an idiopathic inflammatory disorder that is difficult to treat. There is accumulating evidence that constitutive activation of Janus kinase–signal transducer and activator of transcription (JAK‐STAT) signaling occurs in sarcoidosis and ...
William E. Damsky, Bryan D. Young, Brett Sloan, Edward J. Miller, J. A. Obando, B. King   +5 more
semanticscholar   +1 more source