Results 71 to 80 of about 32,573 (255)
GREB1‐rearranged uterine tumours share DNA methylation profiles with UTROSCTs, supporting a close relationship. Despite differences in morphology and genomic complexity, their epigenetic similarity supports the inclusion of these tumours within the UTROSCT spectrum. Background and objectives GREB1‐rearranged uterine tumours encompass a group of uterine
Cheng‐Han Lee +12 more
wiley +1 more source
Mixed low grade and high grade endometrial stromal sarcoma of uterus: Differences on immunohistochemistry and chromosome in situ hybridisation [PDF]
A case of a 64 year old woman with a tumour of the uterus is reported. The patient presented with postmenopausal bleeding and subsequently underwent total hysterectomy and bilateral salpingooophorectomy.
Cheung, ANY, Chung, LP, Khoo, US, Ng, WF
core
Targeting Tumor Dormancy and Recurrence: Molecular Mechanisms and Peptide Therapeutic Delivery
This review summarizes the molecular mechanisms that regulate tumor dormancy and its role in cancer recurrence, with emphasis on immune evasion, extracellular matrix remodeling, metabolic regulation and angiogenic switching. It further discusses emerging peptide–based therapeutic strategies aimed at detecting, modulating, and eliminating dormant tumor ...
Abdur Raheem Aleem +9 more
wiley +1 more source
High-grade endometrial stromal sarcoma harboring ZC3H7B-BCOR fusion is a newly defined entity in gynecologic pathology featuring a set of distinct histopathological and molecular features.
Jerry C. Nagaputra +4 more
doaj +1 more source
Role for growth regulation by estrogen in breast cancer 1 (GREB1) in hormone-dependent cancers [PDF]
Sex hormones play important roles in the onset and progression of several cancers, such as breast, ovarian, and prostate cancer. Although drugs targeting sex hormone function are useful in treating cancer, tumors often develop resistance.
Cheng, Meng +2 more
core +2 more sources
ABSTRACT Nonpuerperal uterine inversion (NPUI) due to endometrial carcinosarcoma can present in an acute manner with life‐threatening complications. The rare presentation of uterine inversion outside of the puerperium caused by a malignant etiology, which was further complicated by the urgent need for intervention, makes this case crucial in ...
Aman Kaur More +3 more
wiley +1 more source
High-grade endometrial stromal sarcoma: a retrospective study of factors influencing prognosis
Objectives The aim of this study was to evaluate the factors associated with progress-free survival (PFS) and overall survival (OS) in patients with high-grade endometrial stromal sarcoma (HG-ESS).
Yan-Yan Zhang +5 more
semanticscholar +1 more source
Unique Molecular Features in High-Risk Histology Endometrial Cancers [PDF]
Endometrial cancer is the most common gynecologic malignancy in the United States and the sixth most common cancer in women worldwide. Fortunately, most women who develop endometrial cancer have low-grade early-stage endometrioid carcinomas, and simple ...
Collins, Kaitlyn +4 more
core +1 more source
Minimal residual disease in solid tumors: Clinical applications and future directions
Abstract Minimal residual disease (MRD) refers to the presence of residual cancer cells or tumor‐derived fragments that persist after treatment and remain undetectable by conventional imaging or protein‐based assays. Circulating tumor DNA (ctDNA) has emerged as a dynamic biomarker for MRD detection.
Theresa Abdo +8 more
wiley +1 more source
Radiogenomics: Current Understandings and Future Perspectives
Radiogenomics links imaging phenotypes with genetic variations, offering potential for comprehensive understanding, cost‐effective diagnosis, and prognosis prediction to advance personalized medicine. However, its clinical application remains limited by several challenges.
Xinyu Zhang +8 more
wiley +1 more source

