Results 71 to 80 of about 19,295 (207)
A Personalised Vaccination Program Based on Immune Reconstitution in Paediatric Cancer Survivors
Acta Paediatrica, EarlyView.ABSTRACT Aims Paediatric cancer survivors often experience treatment‐induced immunosuppression, requiring post‐treatment revaccination. However, immune recovery timelines vary, and current revaccination guidelines, largely based on data of varied quality derived from studies on acute‐lymphoblastic‐leukaemia (ALL), may not be applicable across all ...
Menucha Jurkowicz +17 more
wiley +1 more source
PLoS ONEEwing sarcoma is the second most common bone cancer in children, and while patients who present with metastatic disease at the time of diagnosis have a dismal prognosis.
Ryota Shirai +9 more
doaj +1 more source
Viruses, 2018 About 70% of all Ewing sarcoma (EWS) patients are diagnosed under the age of 20 years. Over the last decades little progress has been made towards finding effective treatment approaches for primarily metastasized or refractory Ewing sarcoma in young ...
Jeannine Lacroix +9 more
doaj +1 more source
Neovascularization in Ewing’s sarcoma
Neoplasma, 2018 Ewing's sarcoma is the second most common bone malignancy in adolescents and young adults after osteosarcoma. Similar to other solid tumors, Ewing's sarcomas require an adequate vascular supply to grow and survive. The development and maintenance of vascular supply is accomplished via three main mechanisms; angiogenesis, vasculogenesis, and tumor cell ...
Mavrogenis, A.F. +4 more
openaire +4 more sources
Superficial Ewing Sarcoma of the Rectum: A Case Report and the Utility of Molecular Diagnostics
Journal of Cutaneous Pathology, EarlyView.ABSTRACT Ewing sarcoma is an undifferentiated small round cell sarcoma that most commonly presents as a malignant bone tumor in pediatric and young adult patients. The diagnosis is typically confirmed by molecular genetic identification of a fusion protein, most commonly involving members of the FET and ETS gene families.
Jessica L. Muldoon +3 more
wiley +1 more source
Primary Ewing sarcoma of the kidney: a symptomatic presentation and review of the literature
Therapeutic Advances in Urology, 2013 The objective of this review is to discuss the unique nature of primary renal Ewing sarcoma, including incidence, presentation and management. We also report on a common pattern of presentation, consisting of acute flank pain mimicking a renal stone ...
Tariq S. Hakky +3 more
doaj +1 more source
Merkel cell carcinoma: an updated guide for pathologists
Histopathology, EarlyView.Merkel cell carcinoma (MCC) is an aggressive cutaneous neuroendocrine carcinoma for which the differential diagnosis can include other small cell malignancies (especially metastatic small cell carcinoma) or cutaneous carcinoma. Morphologic and immunophenotypic aberrancies in MCC can increase diagnostic challenge.
Paul W. Harms
wiley +1 more source
Translational OncologyEwing sarcoma is a highly aggressive solid malignancy affecting children and young adults. Ewing sarcoma is driven primarily by EWSR1::FLI1, a fusion oncoprotein that has been notoriously difficult to target with traditional pharmacologic agents.
Helen F. Gloege +17 more
doaj +1 more source
Novel and emerging cutaneous soft tissue tumours
Histopathology, EarlyView.This review outlines the defining histopathological, immunophenotypic and molecular features of novel and emerging cutaneous soft tissue tumours, including hybrid superficial ALK‐rearranged myxoid spindle cell neoplasm/epithelioid fibrous histiocytoma, superficial neurocristic tumour, ALK‐rearranged epithelioid vascular neoplasm and MITF pathway ...
Saba Shafi, Josephine K Dermawan
wiley +1 more source