Results 91 to 100 of about 244,564 (198)

Evaluating Fine Needle Aspiration Cytology for Diagnostics of Soft Tissue and Bone Tumours

Cytopathology, EarlyView.
Systematic comparison of needle aspiration cytology and histopathology for 503 tumours in soft tissue and bone showed high concordance (positive predictive value 94%–100%, negative predictive value 83%–89%). In this original study, the authors show that FNAC is a safe and non‐invasive method for diagnosing suspected sarcomas, with the main objective to
Amanda Husu, Sandra Wessman, Karin Wallander, Felix Haglund de Flon   +3 more
wiley   +1 more source

Ewing Sarcoma of the Spine: Prognostic Variables for Survival and Local Control in Surgically Treated Patients

Global Spine Journal, 2015
Introduction Primary Ewing sarcoma of the spine is a challenging tumor to treat because of a high rate of local recurrence. The optimum role of surgery in the treatment of Ewing sarcoma is not clearly defined.
Laurence Rhines, Michael Dirks, Stefano Boriani, Alessandro Luzzati, Michael Fehlings, Charles Fisher, Mark Dekutoski, Richard Williams, Nasir Quraishi, Ziya Gokaslan, Chetan Bettegowda, Niccole Germscheid, Peter Varga   +12 more
doaj   +1 more source

Preclinical Testing of an Oncolytic Parvovirus in Ewing Sarcoma: Protoparvovirus H-1 Induces Apoptosis and Lytic Infection In Vitro but Fails to Improve Survival In Vivo

Viruses, 2018
About 70% of all Ewing sarcoma (EWS) patients are diagnosed under the age of 20 years. Over the last decades little progress has been made towards finding effective treatment approaches for primarily metastasized or refractory Ewing sarcoma in young ...
Jeannine Lacroix, Zoltán Kis, Rafael Josupeit, Franziska Schlund, Alexandra Stroh-Dege, Monika Frank-Stöhr, Barbara Leuchs, Jörg R. Schlehofer, Jean Rommelaere, Christiane Dinsart   +9 more
doaj   +1 more source

DNA Methylation Analysis Shows Epigenetic Heterogeneity in Ewing Sarcoma

, 2017
Ewing sarcoma is epigenetically heterogeneous despite the lack of genomic heterogeneity.

core   +1 more source

A guide to transcriptional cyclin‐dependent kinases in cancer

The FEBS Journal, EarlyView.
Transcriptional cyclin‐dependent‐kinases (tCDKs) facilitate gene expression by promoting RNA polymerase II (RNAPII) progression through discrete phases of the transcription cycle. Aberrant tCDK activity is detectable in different human cancers, thereby contributing to de‐regulated gene expression programs that drive oncogenic phenotypes.
Jennifer R. Devlin, Salla Kyheröinen, Ricky W. Johnstone   +2 more
wiley   +1 more source

Ethnicity and age disparties in ewing sarcoma outcome

, 2012
Ethnicity and age disparties in ewing sarcoma ...
KOOHBANANI B, RUGGIERI, PIETRO, HAN G, BUI M. M., REED D, YI D, HENDERSON E   +6 more
core   +1 more source

Salient Features of Mesenchymal Stem Cells – Implications for Ewing Sarcoma Modeling

Frontiers in Oncology, 2013
Despite a heightened appreciation of the many defining molecular aberrations in Ewing sarcoma, the cooperative genetic environment and permissive cell of origin essential for EWS/ETS-mediated oncogenesis remain elusive. Consequently, inducible animal and
Michael James Monument, Nicholas eBernthal, R. Lor eRandall   +2 more
doaj   +1 more source

Ewing Sarcoma: An Eponym Window to History [PDF]

, 2011
Ewing sarcoma was named after James R. Ewing, an eminent American pathologist at Cornell who described the first cases in 1921. Although he is best remembered for this singular achievement, Ewing's contributions to the study of cancer were far more ...
Timothy P. Cripe
core   +1 more source

Supplementary Figure S3 from Ewing Sarcoma Single-cell Transcriptome Analysis Reveals Functionally Impaired Antigen-presenting Cells

, 2023
Cancer-associated fibroblast subsets in Ewing ...
Hans Clevers (17276043), Thanasis Margaritis (17276034), Margit Bleijs (17276031), Frank C. P. Holstege (17276040), Marc van de Wetering (17276037), Lindy L. Visser (15011166)   +5 more
core   +1 more source

Merkel cell carcinoma: an updated guide for pathologists

Histopathology, EarlyView.
Merkel cell carcinoma (MCC) is an aggressive cutaneous neuroendocrine carcinoma for which the differential diagnosis can include other small cell malignancies (especially metastatic small cell carcinoma) or cutaneous carcinoma. Morphologic and immunophenotypic aberrancies in MCC can increase diagnostic challenge.
Paul W. Harms
wiley   +1 more source