Results 91 to 100 of about 24,471 (221)

Salient Features of Mesenchymal Stem Cells – Implications for Ewing Sarcoma Modeling

Frontiers in Oncology, 2013
Despite a heightened appreciation of the many defining molecular aberrations in Ewing sarcoma, the cooperative genetic environment and permissive cell of origin essential for EWS/ETS-mediated oncogenesis remain elusive. Consequently, inducible animal and
Michael James Monument, Nicholas eBernthal, R. Lor eRandall   +2 more
doaj   +1 more source

Fish Tales: Loss of STAG2 Promotes Migration of Ewing Sarcoma

, 2018
Ewing sarcoma (EwS) is a bone and soft tissue cancer affecting children and adolescents. The most unfavorable prognostic factor of EwS is the presence of metastasis, however this process is still poorly understood.
Richardson, Melissa
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MicroRNAs in Ewing Sarcoma

, 2013
MicroRNAs have emerged recently as important regulators of gene expression in the cell. Frequently dysregulated in cancer, microRNAs have shed new light on molecular mechanisms of oncogenesis, and have generated substantial interest as biomarkers, and ...
Paul eJedlicka, Colin Moore, Layne eDylla, Layne Dylla, Colin eMoore, Paul Jedlicka   +5 more
core   +1 more source

Sarcoma de Ewing [PDF]

, 2022
El Sarcoma de Ewing es un tumor de alto grado, en este TFG se pretende realizar una revisión bibliográfica de esta patología realizando énfasis en el diagnóstico, tratamiento, pronóstico y nuevas ...
Martínez Rodríguez, Laura
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A living biobank of sarcoma patient‐derived cell cultures reveals multi‐omic and functional insights that capture disease heterogeneity

Clinical and Translational Medicine, Volume 16, Issue 7, July 2026.
Preclinical models for sarcoma that preserve tumour biology are urgently needed to advance mechanistic understanding and functional precision oncology. 29 early‐passage patient‐derived sarcoma cell (PDC) cultures from 19 patients, representing 11 sarcoma subtypes were established and extensively characterized.
Stefanie Gijsels, Suzanne Fischer, David Creytens, Sándor Dedeyne, Felix De Vuyst, Cláudio Pinheiro, Fleur Cordier, Sarah‐Lee Bekaert, Nadine Van Roy, Kaat Durinck, Jarne Pauwels, Kris Gevaert, Pieter Mestdagh, Jo Vandesompele, Pekka Rappu, Jyrki Heino, An Hendrix, Gabrielle H. van Ramshorst, Gwen Sys, Olivier De Wever   +19 more
wiley   +1 more source

Ewing Sarcoma of the Spine: Prognostic Variables for Survival and Local Control in Surgically Treated Patients

Global Spine Journal, 2015
Introduction Primary Ewing sarcoma of the spine is a challenging tumor to treat because of a high rate of local recurrence. The optimum role of surgery in the treatment of Ewing sarcoma is not clearly defined.
Laurence Rhines, Michael Dirks, Stefano Boriani, Alessandro Luzzati, Michael Fehlings, Charles Fisher, Mark Dekutoski, Richard Williams, Nasir Quraishi, Ziya Gokaslan, Chetan Bettegowda, Niccole Germscheid, Peter Varga   +12 more
doaj   +1 more source

CRISPR‐Cas9 Genome‐Wide Screening in Paediatric Cancer: Functional Genomics for Target Discovery and the Improvement of Existing Therapies

Medicinal Research Reviews, Volume 46, Issue 4, Page 989-1004, July 2026.
ABSTRACT CRISPR‐Cas9 genome‐wide screening has been instrumental towards identifying novel targets for drug discovery in cancer research. However, much of this research has centred specifically on adult cancers, with paediatric cancers being underserviced by current research and screening.
Steven He, Patrick Connerty, Antoine de Weck   +2 more
wiley   +1 more source

Ewing's sarcoma [PDF]

Cancer, 1952
L J, McCORMACK, M B, DOCKERTY, R K, GHORMLEY   +2 more
openaire   +2 more sources

Precision medicine approaches for the management of Ewing sarcoma: current perspectives

, 2019
Victoria T Rizk,1 Christine M Walko,2 Andrew S Brohl3,41University of South Florida Hematology/Oncology Fellowship, 2DeBartolo Family Personalized Medicine Institute, 3Sarcoma Department, 4Chemical Biology and Molecular Medicine Program, H.
Walko CM, Rizk VT, Brohl AS
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Ewing sarcoma [PDF]

, 2004
Ewing sarcoma is an uncommon, highly malignant, primary bone tumor, which is derived from the red bone marrow and it is composed of small blue round cells. Males are affected more frequently than females (1,5:1)
Bozinovska, Biljana, Lazareska, M, Stojanovska, J, Stefanovska, E   +3 more
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