Results 91 to 100 of about 6,019,041 (305)

Risk factors for high anti-HHV-8 antibody titers (≥1:51,200) in black, HIV-1 negative South African cancer patients: a case control study [PDF]

, 2003
Background: Infection with human herpesvirus 8 (HHV-8) is the necessary causal agent in the development of Kaposi's sarcoma (KS). Infection with HIV-1, male gender and older age all increase risk for KS.
Sitas, F., Hale, M., Newton, R., Urban, MI, Wojcicki, J.M., Martin Hale, Bourboulia, D., Newton, R, Bourboulia, D, Wojcicki, JM, Rob Newton, Hale, M, Stein, L., Patel, M, Moosa Patel, Ranjan Sur, Sur, R., Stein, L, Margaret I Urban, Sur, R, Ruff, P, Ruff, P., Lara Stein, Sitas, F ; https://orcid.org/, Janet M Wojcicki, Freddy Sitas, Patel, M., Paul Ruff, Dimitra Bourboulia, Urban, M.I.   +29 more
core   +2 more sources

Biomimetic Scaffold‐Based 3D Models for Decoding Cancer Biology and Advancing Therapy

Advanced Science, EarlyView.
A timeline of the research history of 3D biomimetic scaffold materials and platforms. With advances in biomimetic materials and 3D scaffold technologies, their functional scope has expanded from mimicking basic physical and biochemical properties to increasingly replicating complex pathophysiological processes.
Haitao Zhao, Yuechen Han, Jie Li, Peng Luo, Lin Qi, Zhiwei Xia, Xiaosong Li, Quan Cheng, Chenshen Huang, Wantao Wu, Hao Zhang   +10 more
wiley   +1 more source

In Situ Melanoma of the Nipple and Areola: A Dermoscopic Report in Two New Cases

Dermatology Practical & Conceptual, 2021
Giulio Tosti, Camilla Salvini, Alessia Barisani, Sabina Vaccari   +3 more
doaj   +1 more source

Uterine sarcoma: the possibility of modeling a rare tumor and providing its morphological description

Исследования и практика в медицине
Purpose of the study. To create a model of uterine sarcoma in female white mongrel rats and provide description of its morphological features.Materials and methods.
E. M. Frantsiyants, A. I. Shikhlyarova, I. V. Neskubina, I. V. Kaplieva, L. K. Trepitaki, V. A. Bandovkina, Yu. A. Pogorelova, E. I. Surikova, T. I. Moiseenko, N. D. Cheryarina, E. R. Tolmakh, A. A. Vereskunova, O. G. Ishonina, E. V. Verenikina, A. P. Menshenina   +14 more
doaj   +1 more source

TP53 Loss Elevates NF‐κB‐IFN‐β‐MHC‐Ia Signaling to Promote NK Cell Resistance in Osteosarcoma

Advanced Science, EarlyView.
TP53 loss in a transforming or osteosarcoma cell promotes cytosolic DNA accumulation, activating NF‐κB‐dependent IFN‐β production. Autocrine IFN‐β signaling increases cell‐surface HLA‐Ia expression, strengthens inhibitory KIR signaling in natural killer cells, and thereby enables the affected cell to evade NK cell‐mediated cytotoxicity.
Guihui Qin, Cheung Kwan Yeung, Ye Yi, Dejin Zheng, Miaoman Ye, Chi‐Chong Chio, Jinjie Wu, Siyi Fu, Chu‐Xia Deng, Ren‐He Xu   +9 more
wiley   +1 more source

Modeling CIC::DUX4 sarcoma reveals oncogene-mediated MHCI-dependent immune evasion

Molecular Cancer
CIC::DUX4 sarcoma (CDS) is a highly aggressive malignancy with limited therapeutic options. Here, we present a doxycycline-inducible CIC::DUX4 chimeric mouse model and a cancer line derived from it, imChCDS, that faithfully recapitulates the molecular ...
Ajay Ram Vachanaram, Erdong Wei, Ana Mitanoska, William Bassett, Michael Kyba, Darko Bosnakovski   +5 more
doaj   +1 more source

Melanoma Brain Metastases: Immunotherapy or Targeted Therapy? A Systematic Review and Meta-Analyses

Applied Sciences
Background. Brain metastases are one of the leading causes of death in melanoma patients. This systematic review and meta-analysis aimed to look at the variables that affect melanoma patients’ intracranial treatment responses to immunotherapy and ...
Livia Onofrio, Aurora Gaeta, Oriana D’Ecclesiis, Giovanni Cugliari, Sara Gandini, Paola Queirolo   +5 more
doaj   +1 more source

Experimentally produced synovial sarcomas [PDF]

Cancer, 1966
F N, Ghadially, S, Roy
openaire   +2 more sources

A Versatile DNA‐Encoded Library Platform for the Discovery of Highly Cooperative Chemical Inducers of Proximity

Advanced Science, EarlyView.
We present a versatile DNA‐encoded library (DEL) platform designed for rapid library synthesis and subsequent screening for chemical inducers of proximity (CIPs) across various presenter proteins of choice. Applying this approach, we discovered a novel molecular glue‐like compound mediating CRBN‐BRD9 ternary complex formation with remarkable ...
Bingqi Tong, Sunny A. Tang, Yifan Deng, Zhihan Nan, Alison X. Gao, Gregory A. Michaud, Simone Bonazzi, Frédéric Berst, Frédéric J. Zécri, Shuang Liu, William J. Gibson, Stuart L. Schreiber   +11 more
wiley   +1 more source

Human herpesvirus-8 in hematological diseases

Haematologica, 1998
The huge amount of experimental and clinical observations supporting the possible involvement of human herpesvirus 8 (HHV-8) or Kaposi sarcoma herpesvirus (KSHV) in human lymphoproliferative diseases was critically reviewed during a workshop organized by
G Gaidano, G Torelli
doaj