Results 201 to 210 of about 6,019,041 (305)

Expert consensus on clinical trial design guidelines for FLASH radiotherapy

Precision Radiation Oncology, EarlyView.
• FLASH radiotherapy has emerged as a transformative technology due to the underlying FLASH effect. • As FLASH radiotherapy moves toward clinical application, establishing standardized trial design principles is critical. • This expert consensus provides a roadmap for rigorous clinical evaluation of FLASH radiotherapy, accelerating safe translation of ...
Hui Luo, Chen Cheng, Chengliang Yang, Bing Li, Jiandong Zhang, Jinbo Yue, Zhaoyang Lou, Hui Liu, Jing Cai, Hong Ge   +9 more
wiley   +1 more source

Regulating Lipid Metabolism in Cancer: The Therapeutic Potential of Traditional Chinese Medicine

Phytotherapy Research, EarlyView.
By regulating the reprogramming of lipid metabolism in tumor cells, TCM provides a novel strategy for antitumor therapy with reduced toxicity and enhanced efficacy. ABSTRACT Lipid metabolic reprogramming is a key feature of tumor cells to adapt to the microenvironment and plays an important role in tumor growth, invasion, and metastasis.
Yufeng Gao, Huiming Huang, Xuejiao Wei, Xiaoxue Wang, Wanying Xie, Xinyu Qiu, Fei Wang, Zhuguo Wang, Ruoxin Zhang, Yilin Cai, Changhai Qu, Zhongdong Hu   +11 more
wiley   +1 more source

KSHV Seropositivity Associates With Impaired Immune Reconstitution in Virally Suppressed HIV. [PDF]

Can J Infect Dis Med Microbiol
Wang X, Fang X, Li T, Geng X, Liu Y, Wang S, Wu D, Zhu Y, Wang L.   +8 more
europepmc   +1 more source

Harnessing the nonthermal effects of ultrasound for cancer treatment: From mechanisms to applications

Smart Molecules, EarlyView.
Nonthermal ultrasound transforms acoustic energy into diverse therapeutic bioeffects through cavitation, mechanical stimulation, and physicochemical activation. This review discusses how acoustic parameters, biological mechanisms, and responsive materials interact to influence nonthermal ultrasound‐enabled cancer therapies. Mechanism‐guided engineering
Liu Wang, Huan Tang, Yue Pan, Mingle Li, Weijie Zhao, Kai Liu   +5 more
wiley   +1 more source

Correction: Phase I/II, open-label, multicenter study of durvalumab in combination with tremelimumab in pediatric patients with advanced solid tumors. [PDF]

Front Oncol
Hargrave D, Marshall LV, André N, Krystal J, Ladle BH, Robbins KA, Hois S, Armstrong J, Donegan S.   +8 more
europepmc   +1 more source

Thrombocytosis and tumour distribution predict outcome in dogs with hepatocellular carcinoma: A multi‐institutional retrospective analysis

Veterinary Record, EarlyView.
Abstract Background Hepatocellular carcinoma (HCC) is the most common canine hepatobiliary tumour. This study aimed to determine which criteria influenced outcome of HCC in a modern population of dogs across eight institutions. Methods The medical records of 106 dogs with HCC were retrospectively reviewed.
Emily A. Janik, MacKenzie A. Pellin, Dawn M. Clarke   +2 more
wiley   +1 more source

Neuropeptide Y in cancer metastasis and chemoresistance. [PDF]

Neuropeptides
Krawczyk E, Kitlinska J.
europepmc   +1 more source

Peptide‐directed nanovehicles enabling tumor‐selective ROS amplification and antitumor immunity

VIEW, EarlyView.
Cancer cells are vulnerable to oxidative stress, yet exploit immune tolerance to escape destruction. In contrast, their metabolic profile is markedly altered to support rapid proliferation, accompanied by elevated production of reactive oxygen species (ROS).
Manuela Calin, Galyna Bila, Ileana Manduteanu, Rostyslav Bilyy   +3 more
wiley   +1 more source

Bioinspired TIMP-1 Nanoparticles Mimic Extracellular Vesicle Anti-angiogenic Activity in Ewing Sarcoma. [PDF]

Biomater Res
Liboni C, Boaron M, Corallo D, Aveic S, Ballestri M, Sánchez-Rodríguez R, Testa AM, Ferroni C, Varchi G, Viola A, Angioni R.   +10 more
europepmc   +1 more source

Outcomes in Orbit‐Sparing Versus Orbit‐Sacrificing Surgery for Sinonasal Malignancies With Orbital Involvement: A Systematic Review and Meta‐Analysis

World Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.
ABSTRACT Background Sinonasal malignancies with orbital involvement may be managed with orbit‐sacrificing or orbit‐preserving surgical approaches, with a recent shift towards orbital preservation to reduce postoperative morbidity while maintaining oncological success.
Claire Jing‐Wen Tan, Brian Sheng Yep Yeo, Manish Warrier, Jun He Chan, Lu Hui Png, Shuhui Xu, Kimberley LiQin Kiong, Edward C. Kuan, Tze Choong Charn, Neville Wei Yang Teo   +9 more
wiley   +1 more source