Results 231 to 240 of about 6,019,041 (305)

Broader Familial Cancer Risk in Relatives of Testicular Cancer Patients: Insights From Two Mediterranean Populations

Andrology, EarlyView.
ABSTRACT Background Familial clustering of testicular germ cell tumour (TGCT) is well‐established, whereas the risk of non‐testicular cancer among relatives remains inconsistent across studies. Objective To evaluate the overall and site‐specific cancer risk among first‐degree relatives and grandparents of TGCT patients compared to cancer‐free controls.
Csilla Krausz, Chiara Abrardo, Viktoria Rosta, Daniel Moreno‐Mendoza, Luca Bressan, Matteo Vannucci, Rebecca Passerotti, Arianna Meacci, Ginevra Farnetani, Viola Bonini, Giovanni Corona, Maria Grazia Fino, Eduard Ruiz‐Castañé, Antoni Riera‐Escamilla   +13 more
wiley   +1 more source

Case Report: Surgical management of mandibular oral histiocytic sarcoma in a ragdoll cat with favorable outcome. [PDF]

Front Vet Sci
Seung BJ, Cho J, Lee B, Chon J, Kim K.
europepmc   +1 more source

The Functional Role and Molecular Characterization of the Therapeutic Target CLDN6 in Germ Cell Tumors

Andrology, EarlyView.
ABSTRACT Background The tight junction protein CLDN6 has been identified as a cancer‐associated cell surface marker that is rarely expressed in healthy tissues. In testicular germ cell tumors (GCT), CLDN6 is particularly detectable in seminomas, embryonal carcinomas, and choriocarcinomas.
Jule Zwick, Margaretha A. Skowron, Gereon Poschmann, Patrick Petzsch, Ann Kathrin Bergmann, Kai Stühler, Jochen Hecht, Daniel Nettersheim   +7 more
wiley   +1 more source

RPN1 at the crossroads of glycosylation, tumor immunity, and disulfidptosis. [PDF]

Front Pharmacol
Chang X, Weng L, Yu W, Shen Y.
europepmc   +1 more source

A Spotlight on Yolk‐sac Tumors: Molecular Pathology, Current Diagnostics, and Novel Therapeutics

Andrology, EarlyView.
ABSTRACT Background Yolk‐sac tumors are an aggressive subtype of testicular cancer that significantly contribute to disease progression and therapy resistance, especially in adults. While testicular cancer generally has high cure rates with cisplatin‐based treatment, adult yolk‐sac tumors often appear as components of mixed tumors with poor response to
Evangelos Prokakis, Lisa Schneider, Felix Bremmer, Daniel Nettersheim   +3 more
wiley   +1 more source

Depth and Procedure Specific Effects of Antimicrobial Versus Conventional Sutures on Surgical Site Infection: A Systematic Review and Meta‐Analysis

ANZ Journal of Surgery, EarlyView.
Antimicrobial sutures may be particularly beneficial in colorectal and abdominal procedures, where reductions in deep SSI may offset the additional suture cost. Several studies also reported favorable wound‐healing outcomes. ABSTRACT Background Surgical site infections (SSIs) are common postoperative complications that delay wound healing and increase ...
Ryan Muakkassa, Andrew Roach, Ahmed Adham R. Elsayed, Marc D. Basson   +3 more
wiley   +1 more source

Pediatric patients with cancer exhibit increased neutrophil extracellular traps and reduced active deoxyribonuclease I: diagnostic, prognostic, and therapeutic opportunities. [PDF]

Clin Exp Pediatr
Benavent N, Oto J, Verger P, Herreros-Pomares A, Herranz R, Argilés B, Balaguer J, Juan-Ribelles A, Bonanad S, Medina P, Cañete A.   +10 more
europepmc   +1 more source

Spindle Cell Lesions of the Breast: A 12‐Year Experience

ANZ Journal of Surgery, EarlyView.
This 12‐year, single‐centre study examined 30 core‐biopsy‐diagnosed breast spindle cell lesions (BrSCL), classified as atypical (ASCL, n = 10) or bland (BSCL, n = 20). Following excision, 80% of ASCLs proved malignant, comprising sarcoma, malignant phyllodes tumour and metaplastic carcinoma.
Shalvin Jassal, Wesley Tjang, Shaun Monagle, Michael Law, Justin James   +4 more
wiley   +1 more source

Kaposi Sarcoma-Associated Herpesvirus Is Not Detected in Osteosarcoma From KSHV-Endemic African Countries and the Non-Endemic United States Populations. [PDF]

J Med Virol
Musonda W, Escalante GM, Liang Y, Bardin R, Barasa A, Geel J, Mumba C, Munsaka S, Munthali J, Reidel IG, Ogembo JG.   +10 more
europepmc   +1 more source

Red lines and green lights: Gene therapy for inherited erythroid disorders beyond the haemoglobinopathies

British Journal of Haematology, EarlyView.
Gene therapy is revolutionizing treatment paradigms for haemoglobinopathies, establishing a translational framework for disorders that impact red blood cell development. In their paper, Joshi et al. describe the preclinical and early clinical landscape of gene therapies for non‐haemoglobinopathy erythroid disorders and highlight common thematic ...
Gaurav Joshi, Nandakumar Natarajan, Kathryn E. Dickerson, Richard A. Voit   +3 more
wiley   +1 more source