Results 141 to 150 of about 516,933 (343)

Tissue‐Resident Myeloid and Histiocytic Cells in Health and Disease: Novel Emerging Concepts

open access: yesAmerican Journal of Hematology, EarlyView.
ABSTRACT Although all myeloid cells are considered to derive from hematopoietic stem cells, the cells in each myeloid lineage are heterogeneous populations, and their distribution and functions vary, depending on underlying physiologic and pathologic processes, age, sex, and genetic and epigenetic signatures.
Peter Valent   +27 more
wiley   +1 more source

Recent advances in sarcoma therapy: new agents, strategies and predictive biomarkers

open access: yesJournal of Hematology & Oncology
Soft tissue and bone sarcomas are a heterogenous group of uncommon mesenchymal tumors with high unmet needs for novel therapeutic and diagnostic strategies. Despite many challenges that persist, innovative therapeutics are emerging.
Minggui Pan   +4 more
doaj   +1 more source

Primary reticulum-cell sarcoma of the heart with review of the literature [PDF]

open access: bronze, 1955
Edward A. Brucker, Frank J. Glassy
openalex   +1 more source

CD30 as a Target Molecule in the Diagnosis and Therapy of Lymphomas

open access: yesAmerican Journal of Hematology, EarlyView.
ABSTRACT The tumor necrosis factor (TNF)‐receptor superfamily 8 receptor CD30 molecule is expressed in all tumor cells of Hodgkin lymphoma and anaplastic large cell lymphoma but is only weakly expressed in a small subset of large lymphoid cells in normal peripheral lymphoid tissues.
Harald Stein, Brunangelo Falini
wiley   +1 more source

TBX3‐ Related Disorder

open access: yesAmerican Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Heterozygous pathogenic variants in TBX3 cause Ulnar‐Mammary syndrome (UMS). The phenotype is classically characterized by upper limb defects, apocrine/mammary gland hypoplasia, hypogonadism, and various midline defects. However, the clinical spectrum is highly variable, and some individuals may present with a mild or atypical presentation ...
Ziv Halperin, Karin Weiss
wiley   +1 more source

Tebentafusp (IMCgp100) in the treatment of uveal melanoma — from preclinical evidence to clinical practice

open access: yesNowotwory
Tebentafusp (IMCgp100) is a novel bispecific immunotherapy that contains a specifically engineered soluble T-cellreceptor (TCR) capable of recognising the gp100 epitope on the surface of tumour cells presented by human leukocyteantigen-A*02:01 (HLA- A*02:
Piotr Remiszewski   +8 more
doaj   +1 more source

Pembrolizumab in advanced soft-tissue sarcoma and bone sarcoma (SARC028): a multicentre, two-cohort, single-arm, open-label, phase 2 trial.

open access: yesThe Lancet Oncology, 2017
H. Tawbi   +23 more
semanticscholar   +1 more source

Sinonasal Sarcomas Management: An International Consensus Statement

open access: yesInternational Forum of Allergy &Rhinology, EarlyView.
ABSTRACT Introduction Sinonasal sarcomas are exceedingly rare entities, constituting less than 7% of head and neck sarcomas. Their complex histology needs specialized treatment, which is often based on multimodal approaches including surgery, radiation therapy, and/or chemotherapy.
Alessandro Vinciguerra   +51 more
wiley   +1 more source

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