Results 171 to 180 of about 391,439 (237)

Limited association between HRR gene alterations and HRD in molecular tumor board cancer samples: Who should be tested for HRD?

open access: yesInternational Journal of Cancer, EarlyView.
What's New? Currently, no published data on homologous recombination deficiency (HRD) testing in the setting of molecular tumor boards exist. This study in a cohort of 237 patients encompassing 24 different tumor entities assessed by a molecular tumor board shows that inactivating alterations of BRCA1/2 are not always associated with an elevated ...
Christoph Schubart   +26 more
wiley   +1 more source

Tyrosine kinase inhibitors in Ewing's sarcoma: a systematic review. [PDF]

open access: yesBMC Cancer
Assi A   +9 more
europepmc   +1 more source

Blood‐based biomarkers in soft tissue sarcoma: Implications for immune checkpoint inhibitor therapy

open access: yesInternational Journal of Cancer, EarlyView.
Abstract Soft tissue sarcoma (STS) is a rare and heterogeneous cancer, comprising approximately 1% of all adult cancers and 7%–15% of all childhood cancers. In the advanced stages, chemotherapy remains the standard‐of‐care, but efficacy is limited, with a response rate of 15%–30%, and responses are often short‐lived, with median progression‐free ...
Brie‐Anne Mannah   +2 more
wiley   +1 more source

Cancer incidence in people with HIV in Italy: Comparison of the ICONA COHORT with general population data

open access: yesInternational Journal of Cancer, EarlyView.
What's New? Immune suppression induced by HIV infection significantly increases the risk of certain cancers among people with HIV (PWH). In the present study, the authors investigated cancer incidence among HIV‐infected individuals in Italy using data from the Italian Cohort Naïve Antiretrovirals. Comparison with the corresponding general population in
Pierluca Piselli   +243 more
wiley   +1 more source

Spontaneous conception and pregnancy outcomes after multi‐agent chemotherapy and high‐dose radiotherapy for pelvic Ewing sarcoma: Case report and literature review

open access: yesInternational Journal of Gynecology &Obstetrics, EarlyView.
Abstract Ewing sarcoma is an aggressive, rare bone and soft tissue malignancy, often affecting the long bones and pelvis. A woman was diagnosed with Ewing sarcoma of the left pelvis at 18 years of age. She underwent left paravesical lesion resection with ipsilateral ureteral reimplantation and received combined multi‐agent chemotherapy and high‐dose ...
Valentina Tosto   +6 more
wiley   +1 more source

Topical imiquimod and in situ vulvar melanoma: A promising therapy?

open access: yesInternational Journal of Gynecology &Obstetrics, EarlyView.
Abstract Objectives Vulvar melanoma is a rare type of cancer that affects mainly postmenopausal women. There are no established protocols for the treatment of vulvar melanoma. From data extrapolated from the literature on cutaneous melanoma, surgical excision remains the best option for the resectable disease.
Francesca Pepe   +7 more
wiley   +1 more source

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