Results 171 to 180 of about 734,103 (389)

Early initiation of fast‐track care for persons living with HIV initiating dolutegravir‐based regimens during a period of severe civil unrest in Port‐au‐Prince, Haiti: a pilot randomized trial

Journal of the International AIDS Society
Introduction Differentiated service delivery (DSD) models have been widely implemented for patients in stable HIV care. However, DSD has rarely been offered to newly diagnosed patients.
Jean Bernard Marc, Samuel Pierre, Othnia Ducatel, Fabienne Homeus, Abigail Zion, Vanessa R. Rivera, Nancy Dorvil, Patrice Severe, Colette Guiteau, Vanessa Rouzier, Ingrid T. Katz, Carl Frederic Duchatelier, Guyrlaine Pierre Louis Forestal, Josette Jean, Guirlaine Bernadin, Emelyne Droit Dumont, Rose Cardelle B. Riche, Jean William Pape, Serena P. Koenig   +18 more
doaj   +1 more source

RNAi Regulator C3PO Promotes Arbovirus Infection in Insect Vectors

Advanced Science, EarlyView.
RNA interference (RNAi) is vital for eukaryotes to defend against virus infection. The C3PO complex takes part in RNAi but its role in regulating viral infection remains unclear. This work finds that insect C3PO facilitates arbovirus replication by degrading precursors of miRNAs, especially miR‐971‐3p.
Yan Xiao, Tianyu Guan, Qianfeng Xia, Chen Chen, Qian Wang, Lan Luo, Hong Lu, Feng Cui   +7 more
wiley   +1 more source

Biomechanics‐Driven 3D Architecture Inference from Histology Using CellSqueeze3D

Advanced Science, EarlyView.
CellSqueeze3D reconstructs 3D cellular architecture from standard 2D histology images using biomechanical constraints and optimization. Validated on clinical datasets, it enables accurate tissue phenotyping, predicts gene mutations, and reveals significant correlations between nuclear‐cytoplasmic ratio entropy and tumor progression.
Yan Kong, Hui Lu
wiley   +1 more source

Determinants of Mortality and Disease Progression of Kaposi Sarcoma in a Primary care ART Programme in Khayelitsha, South Africa [PDF]

, 2009
CROI ...
Boulle, A, Chu, K, Ford, Nathan, Mahlangeni, G, Stead, David, Swannet, S, Van Cutsem, G   +6 more
core   +1 more source

Pembrolizumab in advanced soft-tissue sarcoma and bone sarcoma (SARC028): a multicentre, two-cohort, single-arm, open-label, phase 2 trial.

The Lancet Oncology, 2017
H. Tawbi, M. Burgess, V. Bolejack, B. V. Van Tine, S. Schuetze, James Hu, S. D’Angelo, S. Attia, R. Riedel, D. Priebat, S. Movva, L. Davis, S. Okuno, D. Reed, J. Crowley, L. Butterfield, R. Salazar, J. Rodriguez-Canales, A. Lazar, I. Wistuba, L. Baker, R. Maki, D. Reinke, Shreyaskumar R Patel   +23 more
semanticscholar   +1 more source

Thirty Years of Mentoring by “Bob Chan” of Young Japanese Surgeons to Become Scientists: An Adventure of Love

Annals of Gastroenterological Surgery, EarlyView.
ABSTRACT Over the past three decades, we have mentored a generation of young Japanese surgeons, guiding them to become internationally recognized surgeon‐scientists. Through a unique collaboration between Japanese academic institutions and our laboratories at AntiCancer Inc.
Robert M. Hoffman, Kentaro Miyake, Itaru Endo   +2 more
wiley   +1 more source

Recent advances in sarcoma therapy: new agents, strategies and predictive biomarkers

Journal of Hematology & Oncology
Soft tissue and bone sarcomas are a heterogenous group of uncommon mesenchymal tumors with high unmet needs for novel therapeutic and diagnostic strategies. Despite many challenges that persist, innovative therapeutics are emerging.
Minggui Pan, Maggie Zhou, Lu Xie, Nam Bui, Kristen Ganjoo   +4 more
doaj   +1 more source

Tebentafusp (IMCgp100) in the treatment of uveal melanoma — from preclinical evidence to clinical practice

Nowotwory
Tebentafusp (IMCgp100) is a novel bispecific immunotherapy that contains a specifically engineered soluble T-cellreceptor (TCR) capable of recognising the gp100 epitope on the surface of tumour cells presented by human leukocyteantigen-A*02:01 (HLA- A*02:
Piotr Remiszewski, Eryk Siedlecki, Julia Wąż, Kinga Filipek, Agata Pisklak, Wiktor Gaik, Monika Dudzisz-Śledź, Piotr Rutkowski, Anna M. Czarnecka   +8 more
doaj   +1 more source

Clinical implications of six inflammatory biomarkers as prognostic indicators in Ewing sarcoma

, 2017
Yongjiang Li, Xi Yang, Wenbiao Zhang, Cheng Yi, Feng Wang, Ping Li   +5 more
openalex   +2 more sources

Primary Breast Sarcoma: A rare pathology in women from the National Cancer Institute (INCan) of Mexico [PDF]

, 2018
Angélica Morales-Miranda, L Carlos Robles-Vidal, Enrique Bargalló‐Rocha   +2 more
openalex   +1 more source