Results 11 to 20 of about 734,103 (389)
Soft Tissue Sarcoma, Version 2.2022, NCCN Clinical Practice Guidelines in Oncology.
The Journal of the National Comprehensive Cancer Network, 2022 Soft tissue sarcomas (STS) are rare malignancies of mesenchymal cell origin that display a heterogenous mix of clinical and pathologic characteristics. STS can develop from fat, muscle, nerves, blood vessels, and other connective tissues.
M. von Mehren +33 more
semanticscholar +1 more source
Sarcoma classification by DNA methylation profiling
Nature Communications, 2021 Sarcomas are malignant soft tissue and bone tumours affecting adults, adolescents and children. They represent a morphologically heterogeneous class of tumours and some entities lack defining histopathological features.
C. Koelsche +110 more
semanticscholar +1 more source
Clinical genomic profiling in the management of patients with soft tissue and bone sarcoma
Nature Communications, 2022 There are more than 70 distinct sarcomas, and this diversity complicates the development of precision-based therapeutics for these cancers. Prospective comprehensive genomic profiling could overcome this challenge by providing insight into sarcomas ...
M. Gounder +42 more
semanticscholar +1 more source
Synovial Sarcoma: A Clinical Review
Current Oncology, 2021 Synovial sarcomas (SS) represent a unique subset of soft tissue sarcomas (STS) and account for 5–10% of all STS. Synovial sarcoma differs from other STS by the relatively young age at diagnosis and clinical presentation.
A. Gazendam +5 more
semanticscholar +1 more source
B cells are associated with survival and immunotherapy response in sarcoma
Nature, 2020 Soft-tissue sarcomas represent a heterogeneous group of cancer, with more than 50 histological subtypes1,2. The clinical presentation of patients with different subtypes is often atypical, and responses to therapies such as immune checkpoint blockade ...
F. Petitprez +28 more
semanticscholar +1 more source
Cancer Communications, 2020 Low‐grade endometrial stromal sarcoma (LG‐ESS) is a rare tumor that lacks a prognostic prediction model. Our study aimed to develop a nomogram to predict overall survival of LG‐ESS patients.
Jie Wu +6 more
semanticscholar +1 more source
Nature Reviews Disease Primers, 2019 Cecilia Taverna, Alessandro Franchi
semanticscholar +4 more sources
Sarcoma treatment in the era of molecular medicine
EMBO Molecular Medicine, 2020 Sarcomas are heterogeneous and clinically challenging soft tissue and bone cancers. Although constituting only 1% of all human malignancies, sarcomas represent the second most common type of solid tumors in children and adolescents and comprise an ...
T. Grünewald +41 more
semanticscholar +1 more source
Larotrectinib in a NTRK‐rearranged soft tissue sarcoma in the neoadjuvant setting: A case report
Clinical Case Reports, 2021 Patients with soft tissue sarcomas should be assessed for neurotrophic tropomyosin receptor kinase (NTRK) gene fusions as neoadjuvant treatment with larotrectinib may prevent amputation.
Catherine Percy +4 more
doaj +1 more source
JCO Global Oncology, 2021 PURPOSEIn Scotland, approximately 350 sarcoma cases are diagnosed per year and treated in one of the five specialist centers. Many patients are required to travel long distances to access specialist care.
Holly M. McCabe +14 more
doaj +1 more source