Results 221 to 230 of about 516,933 (343)

DNA methylation heterogeneity defines a disease spectrum in Ewing sarcoma

Nature Network Boston, 2017
Nathan C. Sheffield, G. Pierron, J. Klughammer, Paul Datlinger, Andreas Schönegger, M. Schuster, J. Hadler, Didier Surdez, D. Guillemot, E. Lapouble, P. Fréneaux, J. Champigneulle, R. Bouvier, D. Walder, I. Ambros, C. Hutter, Eva Sorz, A. Amaral, E. de Álava, K. Schallmoser, D. Strunk, B. Rinner, B. Liegl-Atzwanger, B. Huppertz, A. Leithner, G. de Pinieux, P. Terrier, V. Laurence, J. Michon, R. Ladenstein, W. Holter, R. Windhager, U. Dirksen, P. Ambros, O. Delattre, H. Kovar, C. Bock, E. Tomazou   +37 more
semanticscholar   +1 more source

Mechanisms of enhancer‐driven oncogene activation

International Journal of Cancer, EarlyView.
Abstract An aggressive subtype of acute myeloid leukemia (AML) is caused by enhancer hijacking resulting in MECOM overexpression. Several chromosomal rearrangements can lead to this: the most common (inv(3)/t(3;3)) results in a hijacked GATA2 enhancer, and there are several atypical MECOM rearrangements involving enhancers from other hematopoietic ...
Joyce Vriend, Ruud Delwel, Dorien Pastoors   +2 more
wiley   +1 more source

Chest Wall Reconstruction in Ewing Sarcoma Using a Radioprotective Spacer. [PDF]

Surg Case Rep
Yoshizawa H, Terui K, Nakata M, Takenouchi A, Komatsu S, Oita S, Kawaguchi Y, Nishimura K, Kudo W, Ozeki G, Hino M, Okunushi T, Yamashita Y, Harada R, Hattori S, Hishiki T.   +15 more
europepmc   +1 more source

COEXISTING INFECTION AND SARCOMA OF THE THYROID

, 1913
MILES F. PORTER
openalex   +2 more sources

Sarcoma botryoides in the female urogenital tract [PDF]

, 1954
William B. Ober, John H. Edgcomb
openalex   +1 more source

Improved survival using specialized multidisciplinary board in sarcoma patients

Annals of Oncology, 2017
Jean-Yves Blay, P. Soibinet, Nicolas Penel, E. Bompas, F. Duffaud, E. Stoeckle, O. Mir, J. Adam, C. Chevreau, S. Bonvalot, M. Ríos, P. Kerbrat, D. Cupissol, P. Anract, F. Gouin, J. Kurtz, C. Lebbé, N. Isambert, F. Bertucci, M. Toumonde, A. Thyss, S. Piperno-Neumann, P. Dubray-Longeras, P. Meeus, F. Ducimetière, A. Giraud, J. Coindre, I. Ray-Coquard, A. Italiano, A. Cesne   +29 more
semanticscholar   +1 more source

Therapeutic targeting of chromatin alterations in leukemia and solid tumors

International Journal of Cancer, EarlyView.
Abstract Alterations in chromatin conformation and post‐translational modification of histones have become increasingly recognized as critical drivers of cancer development, progression, and therapy resistance. Recent advances in drug development have led to the establishment of several highly selective small molecule inhibitors, several of which are ...
Florian Perner, Tobias Berg, Daniel Sasca, Sophie‐Luise Mersiowsky, Jayant Y. Gadrey, Johanna Thomas, Michael W. M. Kühn, Michael Lübbert   +7 more
wiley   +1 more source

Triangulating Timing, Tropism and Burden of Sarcoma Metastases: Toward Precision Surveillance and Therapy in a Real-World-Time Cohort. [PDF]

Cancers (Basel)
Heesen P, Feusi D, Vogel B, Studer G, Fuchs B, On Behalf Of The Swiss Sarcoma Network.   +5 more
europepmc   +1 more source

The pathogenesis of experimentally produced lymphomata in rats (including Hodgkin's-like sarcoma) [PDF]

, 1952
J Gillman, Theodore Gillman
openalex   +1 more source

Deregulated enhancer‐promoter communication in cancer through altered nuclear architecture

International Journal of Cancer, EarlyView.
Abstract Enhancers are critical regulators of gene expression. Structural variations in cancer genomes can lead to enhancer hijacking, where oncogenes are activated by mistargeted enhancer activity. Novel enhancer‐promoter interactions may also arise through chromosomal rearrangements that create extrachromosomal DNA elements.
Isabelle Seufert, Claire Vargas, Sina Jasmin Wille, Karsten Rippe   +3 more
wiley   +1 more source