Results 291 to 300 of about 42,993 (322)
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, 2020
Recent advances in stem cell biology have allowed researchers to efficiently produce large numbers of cardiomyocytes from various pluripotent cell sources.
M. Salick +5 more
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Recent advances in stem cell biology have allowed researchers to efficiently produce large numbers of cardiomyocytes from various pluripotent cell sources.
M. Salick +5 more
semanticscholar +1 more source
The Sarcomere and Sarcomerogenesis
2008Striated muscle owes its name to the microscopic appearance, caused by the longitudinal alignment of thousands of highly ordered contractile units, the sarcomeres. The assembly (and disassembly) of these multiprotein complexes (sarcomere assembly or sarcomerogenesis) follows ordered pathways, which are regulated on the transcriptional, translational ...
Ehler, E, Gautel, M
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Atomistic Simulations of Sarcomere Proteins
2023Concerted atomic motions are requisite for sarcomere protein function and may become disrupted in HCM pathologies. Computational approaches such as molecular dynamics simulation can resolve such dynamics with unrivalled spatial and temporal resolution.
Matthew Carter, Childers +1 more
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Sarcomeric Genotyping in Hypertrophic Cardiomyopathy
Mayo Clinic Proceedings, 2005To pool results from studies of patients with hypertrophic cardiomyopathy (HCM) to elucidate important phenotypic differences among genotypes.Data published from November 1998 through November 2004 were gathered and compared from unrelated study population genotyping studies from the Mayo Clinic (Rochester, Minn), Harvard Medical School (Boston, Mass),
Sara L, Van Driest +4 more
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Myofilaments: Movers and Rulers of the Sarcomere.
Comprehensive Physiology, 2017Striated cardiac and skeletal muscles play very different roles in the body, but they are similar at the molecular level. In particular, contraction, regardless of the type of muscle, is a precise and complex process involving the integral protein ...
B. Lin, Taejeong Song, S. Sadayappan
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Inherited disorders of sarcomeric proteins
Current Opinion in Neurology, 1999The most important advances in sarcomeric protein diseases continue to be the identification of mutated genes responsible for human diseases. These have recently included those that encode skeletal muscle alpha-actin in autosomal dominant and autosomal recessive nemaline myopathy, nebulin and slow alpha-tropomyosin in autosomal recessive nemaline ...
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Beef tenderness and sarcomere length
Meat Science, 1990A wide range of muscle glycolytic rates was produced in 60 beef carcasses by applying different forms and periods of electrical stimulation immediately after decapitation; a further seven carcasses were not stimulated. The sides were subjected to normal chilling, and at 48 h one short loin per carcass was taken for tenderness evaluation and ...
F J, Smulders +4 more
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2010
Skeletal muscle cells, more commonly called muscle fibres, are multinucleated syncytia formed during development by fusion of mononucleated precursor cells, the myoblasts. They measure 10–100 μm in diameter and can have lengths from a few millimeters up to almost a meter.
Margit Pavelka, Jürgen Roth
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Skeletal muscle cells, more commonly called muscle fibres, are multinucleated syncytia formed during development by fusion of mononucleated precursor cells, the myoblasts. They measure 10–100 μm in diameter and can have lengths from a few millimeters up to almost a meter.
Margit Pavelka, Jürgen Roth
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Spatial sub-sarcomeric proteomic analysis reveals novel sarcomeric proteins
Journal of Molecular and Cellular Cardiology, 2022Rami Haddad +5 more
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Sarcomere Function and Crossbridge Cycling
1995The power of the heart is dictated by the force development and velocity of shortening (V) of the cardiac sarcomere. Both depend on the amount of Ca++ released by the sarcoplasmic reticulum during the action potential. We have investigated the inter-relationship between force (F) sarcomere length (SL) and V and the intracellular Ca++ concentration ([Ca+
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