Results 221 to 230 of about 30,048 (267)

Blockage of autophagy causes severe skeletal muscle disruption in a mouse model for myofibrillar myopathy 6. [PDF]

open access: yesNat Commun
Filippi K   +18 more
europepmc   +1 more source
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Force produced by isolated sarcomeres and half-sarcomeres after an imposed stretch

American Journal of Physiology - Cell Physiology, 2012
When a stretch is imposed to activated muscles, there is a residual force enhancement that persists after the stretch; the force is higher than that produced during an isometric contraction in the corresponding length. The mechanisms behind the force enhancement remain elusive, and there is disagreement if it represents a sarcomeric property, or if it
Rassier D E, Ivan Pavlov
exaly   +4 more sources

Foci of Segmentally Contracted Sarcomeres in Trapezius Muscle Biopsy Specimens in Myalgic and Nonmyalgic Human Subjects: Preliminary Results.

Pain medicine (Malden, Mass.), 2020
OBJECTIVE The myofascial trigger point hypothesis postulates that there are small foci of contracted sarcomeres in resting skeletal muscle. Only one example, in canine muscle, has been published previously.
R. Gerwin   +5 more
semanticscholar   +1 more source

The Sarcomere and Sarcomerogenesis

2008
Striated muscle owes its name to the microscopic appearance, caused by the longitudinal alignment of thousands of highly ordered contractile units, the sarcomeres. The assembly (and disassembly) of these multiprotein complexes (sarcomere assembly or sarcomerogenesis) follows ordered pathways, which are regulated on the transcriptional, translational ...
Ehler, E, Gautel, M
openaire   +2 more sources

On the isometric equation of the sarcomere

Basic Research in Cardiology, 1974
A model of the sarcomere is described, which is based upon (a) the sliding filament theory ofHuxley, (b) the ultrastructure of the sarcomere, (c) the biochemical mechanisms responsible for mechanical coupling and uncoupling of myosin and actin, (d) the constancy of the volume of the sarcomere and (e) a statistical analysis of random forces acting on ...
P J, Lewi, W K, Schaper, L M, Gijpen
openaire   +2 more sources

Dysfunctional sarcomeric relaxation in the heart

Current Opinion in Physiology, 2022
Since cardiac relaxation is commonly impaired in heart failure caused by many different etiologies, identifying druggable targets is a common goal. While many factors contribute to cardiac relaxation, this review focuses on sarcomeric relaxation and dysfunction.
Walter E, Knight, Kathleen C, Woulfe
openaire   +2 more sources

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