Results 221 to 230 of about 19,099 (312)

Dynamic Modulation of the Microenvironment Promotes Functional Maturation of Engineered Tissues. [PDF]

open access: yesAdv Healthc Mater
Silberman E   +7 more
europepmc   +1 more source

Reviewer #2 (Public review): Human formin FHOD3-mediated actin elongation is required for sarcomere integrity in cardiomyocytes [PDF]

open access: gold
Dylan A Valencia   +7 more
openalex   +1 more source

Architecture of lower leg muscles in children: Reference curves and potential mechanisms of growth

open access: yesJournal of Anatomy, Volume 249, Issue 1, Page 54-67, July 2026.
Muscle architecture (physiological cross‐sectional area, fascicle lengths and pennation angle) was measured from multimodal MRI scans of the lower legs of 197 children aged ≤15 years. We showed that lower leg muscle volumes (product of PCSA and fascicle length) increase primarily through increases in PCSA (transverse growth) rather than increases in ...
Brian V. Y. Chow   +12 more
wiley   +1 more source

Novel MYL1 Intron Variant With Expanded Phenotype

open access: yesAmerican Journal of Medical Genetics Part A, Volume 200, Issue 6, Page 1378-1383, June 2026.
ABSTRACT Congenital myopathy‐14 (CMYO14) is an ultrarare autosomal recessive disorder caused by biallelic variants in MYL1, with only four patients reported to date. We describe what is likely the fifth reported patient, a neonate with severe hypotonia, respiratory insufficiency, and skeletal anomalies showing distinct histological changes of skeletal ...
Maria Barington   +7 more
wiley   +1 more source

Reduced Expression of MTSS1 Increases Sarcomere Number and Improves Contractility in Select Forms of Monogenic DCM. [PDF]

open access: yesJACC Basic Transl Sci
Kleppe H   +14 more
europepmc   +1 more source

Peripartum Cardiomyopathy Presenting With Severe Biventricular Dysfunction, Valvular Regurgitation, and Familial Predisposition: A Case Report

open access: yesClinical Case Reports, Volume 14, Issue 6, June 2026.
ABSTRACT Peripartum cardiomyopathy (PPCM) is defined as the onset of left ventricular systolic dysfunction either during pregnancy or up to 5 months after delivery, without any other known cause of heart failure. The exact pathogenesis of this disease is unknown, and its prognosis remains poorly understood.
Muhammad Ibrahim Shah   +4 more
wiley   +1 more source

Titin's P-zone domains A164-167 are essential for thick filament structural arrangement. [PDF]

open access: yesJ Gen Physiol
Hoover Browne C   +10 more
europepmc   +1 more source

Biomaterial Physical Cues as Gene Regulators for Cellular Agriculture

open access: yesAdvanced Genetics, Volume 7, Issue 2, June 2026.
This review elucidates how biomaterial physical cues—ranging from matrix stiffness to remote electromagnetic fields—serve as extrinsic regulators of gene expression in cellular agriculture. By identifying central mechanotransduction pathways that bridge physical inputs to genetic remodeling, the authors propose the “Material Genome” concept: a ...
Jianuo Liu, Ye Liu
wiley   +1 more source

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