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Myofilaments: Movers and Rulers of the Sarcomere

Comprehensive Physiology, 2017
ABSTRACT Striated cardiac and skeletal muscles play very different roles in the body, but they are similar at the molecular level. In particular, contraction, regardless of the type of muscle, is a precise and complex process involving the integral protein myofilaments and their associated regulatory components ...
Brian Leei, Lin   +2 more
openaire   +2 more sources

Myofibrils and Sarcomere

2010
Skeletal muscle cells, more commonly called muscle fibres, are multinucleated syncytia formed during development by fusion of mononucleated precursor cells, the myoblasts. They measure 10–100 μm in diameter and can have lengths from a few millimeters up to almost a meter.
Margit Pavelka, Jürgen Roth
openaire   +1 more source

Mechanics of the Sarcomere

1989
Studies on the mechanics of sarcomeres at the level of single myofibrils or single myocytes revealed properties not predicted by the cross-bridge theory of muscle contraction. This paper summarizes four major aspects: 1. Passive compression of the sarcomere showed two inflections in the force length curve; one was at the length where opposing ...
openaire   +1 more source

Architecture and function in the muscle sarcomere

Current Opinion in Structural Biology, 1997
Striated muscle sarcomeres in vertebrates comprise ordered arrays of actin and myosin filaments, organized by an elaborate protein scaffold. Recent innovative work in a number of laboratories has greatly improved our knowledge of these structures, their organization and their interactions.
openaire   +2 more sources

Super relaxed myosins loosen up to different cues in cardiac and skeletal muscle sarcomeres

Journal of General Physiology, 2023
Wout Claassen, Coen Ottenheijm
exaly  

Sarcomeres

2012
Gordon S. Lynch   +22 more
openaire   +1 more source

Sarcomere

2013
openaire   +1 more source

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