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What Can We Learn from Single Sarcomere and Myofibril Preparations?
Sarcomeres are the smallest functional contractile unit of muscle, and myofibrils are striated muscle organelles that are comprised of sarcomeres that are strictly aligned in series.
Walter Herzog
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In vivo Sarcomere Lengths and Sarcomere Elongations Are Not Uniform across an Intact Muscle [PDF]
Sarcomere lengths have been a crucial outcome measure for understanding and explaining basic muscle properties and muscle function. Sarcomere lengths for a given muscle are typically measured at a single spot, often in the mid-belly of the muscle, and at a given muscle length.
Herzog, Walter +4 more
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CONTRACTILE PROTEIN NUMBER IN ADJACENT SARCOMERES – IS THERE A DIFFERENCE? [PDF]
INTRODUCTION Variation in sarcomere length within an actively contracting skeletal muscle has often been observed yet remains unexplained. Sarcomeres within a myofibril are connected in series and thus they must each produce the same amount of force [1].
Antwi-Nsiah, Hilda +2 more
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The force of the myosin motor sets cooperativity in thin filament activation of skeletal muscles
Sarcomeres of Ca2 + -activated demembranated fibres of rabbit soleus muscles show that the stress exerted by each motor protein on the thin filament determines the cooperativity in thin filament activation.
Marco Caremani +9 more
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Force–length relation of skeletal muscles: from sarcomeres to myofibril [PDF]
Sarcomeres are building blocks of skeletal muscles. Given force–length relations of sarcomeres serially connected in a myofibril, the myofibril force–length relation can be uniquely determined.
Hou, M.
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2019 Honorable Mention, Northwestern Scientific Images Contest. This image captures muscle sarcomeres (consecutive green lines), the smallest functional unit of muscle, from inside a living human. The mesmerizing periodicity in the image is the naturally
Adkins, Amy Nicole
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Titin-dependent biomechanical feedback tailors sarcomeres to specialized muscle functions in insects [PDF]
Sarcomeres are the universal contractile units of muscles that enable animals to move. Insect muscles display a remarkable functional diversity: they operate at extremely different contraction frequencies (ranging from ~1 to 1000 hertz) and amplitudes ...
Luis, Nuno Miguel +10 more
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The aim of this study was to describe the structural and ultrastructural aspects of the myotendinous junction (MTJ) and the proximal and distal sarcomeres of the sternomastoid of aged Wistar rats subjected to an experimental model of menopause and ...
Carolina dos Santos Jacob +4 more
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Isolated adult rat ventricular cardiomyocytes (ARVC) adapt to the two-dimensional surface of culture dishes once they are isolated from the three-dimensional heart tissue.
Antonia Petersen +5 more
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Myofibril Changes in the Copepod Pseudodiaptomus marinus Exposed to Haline and Thermal Stresses. [PDF]
Copepods are small crustaceans capable to survive in various aquatic environments. Their responses to changes in different external factors such as salinity and temperature can be observed at different integration levels from copepod genes to copepod ...
Ali Ibrahim +5 more
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