Results 41 to 50 of about 30,048 (267)

Titin stiffness modifies the force-generating region of muscle sarcomeres

Scientific Reports, 2016
The contractile units of striated muscle, the sarcomeres, comprise the thick (myosin) and thin (actin) filaments mediating active contraction and the titin filaments determining “passive” elasticity.
Yong Li, Patrick Lang, W. Linke
semanticscholar   +1 more source

Breaking sarcomeres by in vitro exercise

Scientific Reports, 2016
Eccentric exercise leads to focal disruptions in the myofibrils, referred to as “lesions”. These structures are thought to contribute to the post-exercise muscle weakness and to represent areas of mechanical damage and/or remodelling.
Z. Orfanos, Markus Gödderz, E. Soroka, Tobias Gödderz, Anastasia Rumyantseva, P. V. D. van der Ven, T. Hawke, D. Fürst   +7 more
semanticscholar   +1 more source

Effects of physical training on sarcomere lengths and muscle-tendon interface of the cervical region in an experimental model of menopause

European Journal of Histochemistry, 2019
The aim of this study was to describe the structural and ultrastructural aspects of the myotendinous junction (MTJ) and the proximal and distal sarcomeres of the sternomastoid of aged Wistar rats subjected to an experimental model of menopause and ...
Carolina dos Santos Jacob, Lara Caetano Rocha, Jurandyr Pimentel Neto, Ii-sei Watanabe, Adriano Polican Ciena   +4 more
doaj   +1 more source

Induction of Proteasome Subunit Low Molecular Weight Protein (LMP)-2 Is Required to Induce Active Remodeling in Adult Rat Ventricular Cardiomyocytes

Medical Sciences, 2020
Isolated adult rat ventricular cardiomyocytes (ARVC) adapt to the two-dimensional surface of culture dishes once they are isolated from the three-dimensional heart tissue.
Antonia Petersen, Hanna Sarah Kutsche, Franziska Nippert, Rolf Schreckenberg, Rainer Schulz, Klaus-Dieter Schlüter   +5 more
doaj   +1 more source

Myofibril Changes in the Copepod Pseudodiaptomus marinus Exposed to Haline and Thermal Stresses. [PDF]

PLoS ONE, 2016
Copepods are small crustaceans capable to survive in various aquatic environments. Their responses to changes in different external factors such as salinity and temperature can be observed at different integration levels from copepod genes to copepod ...
Ali Ibrahim, Anissa Souissi, Aymeric Leray, Laurent Héliot, Bernard Vandenbunder, Sami Souissi   +5 more
doaj   +1 more source

Sarcomeres pattern proprioceptive sensory dendritic endings through Perlecan/UNC-52 in C. elegans

Developmental Cell, 2015
Sensory dendrites innervate peripheral tissues through cell-cell interactions that are poorly understood. The proprioceptive neuron PVD in C. elegans extends regular terminal dendritic branches between muscle and hypodermis.
Xing Liang, Xintong Dong, D. Moerman, K. Shen, Xiangming Wang   +4 more
semanticscholar   +1 more source

Polarization-resolved microscopy reveals a muscle myosin motor-independent mechanism of molecular actin ordering during sarcomere maturation.

PLoS Biology, 2018
Sarcomeres are stereotyped force-producing mini-machines of striated muscles. Each sarcomere contains a pseudocrystalline order of bipolar actin and myosin filaments, which are linked by titin filaments.
Olivier Loison, Manuela Weitkunat, Aynur Kaya-Çopur, Camila Nascimento Alves, Till Matzat, Maria L Spletter, Stefan Luschnig, Sophie Brasselet, Pierre-François Lenne, Frank Schnorrer   +9 more
doaj   +1 more source

Myocardial ultrastructure can augment genetic testing for sporadic dilated cardiomyopathy with initial heart failure

ESC Heart Failure, 2021
Aims The aim of the present study was to consider whether the ultrastructural features of cardiomyocytes in dilated cardiomyopathy can be used to guide genetic testing.
Tsunenori Saito, Naoko Saito Sato, Kosuke Mozawa, Akiko Adachi, Yoshihiro Sasaki, Kotoka Nakamura, Eiichiro Oka, Toshiaki Otsuka, Eitaro Kodani, Kuniya Asai, Kyoichi Mizuno, Wataru Shimizu, Roberta A. Gottlieb   +12 more
doaj   +1 more source

Regulation of the evolutionarily conserved muscle myofibrillar matrix by cell type dependent and independent mechanisms

Nature Communications, 2022
Recent work has shown that mammalian muscle cells are comprised of multiple branching sarcomeres, though how this connectivity is regulated has remained unknown.
Peter T. Ajayi, Prasanna Katti, Yingfan Zhang, T. Bradley Willingham, Ye Sun, Christopher K. E. Bleck, Brian Glancy   +6 more
doaj   +1 more source

Characterization of the myosin-based source for second-harmonic generation from muscle sarcomeres.

Biophysical Journal, 2006
Several biologically important protein structures give rise to strong second-harmonic generation (SHG) in their native context. In addition to high-contrast optical sections of cells and tissues, SHG imaging can provide detailed structural information ...
Sergey V Plotnikov, A. Millard, P. Campagnola, W. Mohler   +3 more
semanticscholar   +1 more source