Results 31 to 40 of about 17,660 (277)
New indexes for myofibril linearity in muscle image analysis
European Journal of Translational Myology, 2022 The endeavor to evaluate the linearity of myofibrillar structures and their potential deviation from a straight line is a fascinating problem in muscle tissue image analysis.
Ettore Rocchi +3 more
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Cooperation between myofibril growth and costamere maturation in human cardiomyocytes
Frontiers in Bioengineering and Biotechnology, 2022 Costameres, as striated muscle-specific cell adhesions, anchor both M-lines and Z-lines of the sarcomeres to the extracellular matrix. Previous studies have demonstrated that costameres intimately participate in the initial assembly of myofibrils ...
Huaiyu Shi +8 more
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Microtubules orchestrate local translation to enable cardiac growth
Nature Communications, 2021 New contractile units are required during cardiac hypertrophy, though it remains unclear precisely where and how these new sarcomeres are added. Here the authors reveal that in the heart, microtubules spatiotemporally regulate mRNAs and ribosomes to ...
Emily A. Scarborough +8 more
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Distorting the sarcomere [PDF]
Journal of General Physiology, 2010 One of the goals of cardiovascular science is to create a mathematical model of the heart that can predict ventricular function in healthy and diseased states, and that can be used to help improve treatment options for patients with heart disease. To be clinically useful, the model will have to include structural information about the shapes of the ...
openaire +2 more sources
Foci of segmentally contracted sarcomeres in trapezius muscle biopsy specimens in myalgic and nonmyalgic human subjects : preliminary results [PDF]
, 2020 Objective The myofascial trigger point hypothesis postulates that there are small foci of contracted sarcomeres in resting skeletal muscle. Only one example, in canine muscle, has been published previously.
Gerwin, Robert D. +5 more
core +1 more source
Frontiers in Physiology, 2022 Myofibrillogenesis is an essential process for cardiogenesis and is closely related to excitation-contraction coupling and the maintenance of heartbeat.
Nobutoshi Ichise +9 more
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Spontaneous sarcomere dynamics [PDF]
Chaos: An Interdisciplinary Journal of Nonlinear Science, 2010 Sarcomeres are the basic force generating units of striated muscles and consist of an interdigitating arrangement of actin and myosin filaments. While muscle contraction is usually triggered by neural signals, which eventually set myosin motors into motion, isolated sarcomeres can oscillate spontaneously between a contracted and a relaxed state.
Gunther, Stefan, Kruse, Karsten
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Rapid IFM Dissection for Visualizing Fluorescently Tagged Sarcomeric Proteins
Bio-Protocol, 2017 Sarcomeres, the smallest contractile unit of muscles, are arguably the most impressive actomyosin structure. Yet a complete understanding of sarcomere formation and maintenance is missing.
Yu Shu Xiao +2 more
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Lateral Communication between Stress Fiber Sarcomeres Facilitates a Local Remodeling Response [PDF]
, 2012 Actin stress fibers (SFs) are load-bearing and mechanosensitive structures. To our knowledge, the mechanisms that enable SFs to sense and respond to strain have not been fully defined. Acute local strain events can involve a twofold extension of a single
Chapin, Laura M. +4 more
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Muscle-specific stress fibers give rise to sarcomeres in cardiomyocytes
eLife, 2018 The sarcomere is the contractile unit within cardiomyocytes driving heart muscle contraction. We sought to test the mechanisms regulating actin and myosin filament assembly during sarcomere formation.
Aidan M Fenix +15 more
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