Results 21 to 30 of about 30,048 (267)
Sarcomere mechanics in striated muscles: from molecules to sarcomeres to cells. [PDF]
American Journal of Physiology-Cell Physiology, 2017 Muscle contraction is commonly associated with the cross-bridge and sliding filament theories, which have received strong support from experiments conducted over the years in different laboratories. However, there are studies that cannot be readily explained by the theories, showing 1) a plateau of the force-length relation extended beyond optimal ...
D. Rassier
semanticscholar +3 more sources
Fluid flow in the sarcomere [PDF]
Archives of Biochemistry and Biophysics, 2021 A highly organized and densely packed lattice of molecular machinery within the sarcomeres of muscle cells powers contraction. Although many of the proteins that drive contraction have been studied extensively, the mechanical impact of fluid shearing within the lattice of molecular machinery has received minimal attention. It was recently proposed that
Sage A. Malingen +4 more
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eLife, 2023 Sarcomeres are the basic contractile units within cardiac myocytes, and the collective shortening of sarcomeres aligned along myofibrils generates the force driving the heartbeat.
Abigail C Neininger-Castro +7 more
doaj +1 more source
Reviews in Cardiovascular Medicine, 2022 Restrictive cardiomyopathy (RCM) is an uncommon cardiac muscle disease characterized by impaired ventricular filling and severe diastolic dysfunction with or without systolic dysfunction.
Zhe Yang, Jia Chen, Hong Li, Yubi Lin
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Cells, 2021 Life-threatening ventricular arrhythmias are the main clinical burden in patients with hypertrophic cardiomyopathy (HCM), and frequently occur in young patients with mild structural disease.
Lorenzo Santini +2 more
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New indexes for myofibril linearity in muscle image analysis
European Journal of Translational Myology, 2022 The endeavor to evaluate the linearity of myofibrillar structures and their potential deviation from a straight line is a fascinating problem in muscle tissue image analysis.
Ettore Rocchi +3 more
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Sarcomeres regulate murine cardiomyocyte maturation through MRTF-SRF signaling
Proceedings of the National Academy of Sciences of the United States of America, 2020 Significance Mature cardiomyocytes are highly adapted to pump efficiently over billions of cycles. The mechanisms that regulate and coordinate the acquisition of the specialized features of mature cardiomyocytes in the postnatal period are not well ...
Yuxuan Guo +12 more
semanticscholar +1 more source
Cooperation between myofibril growth and costamere maturation in human cardiomyocytes
Frontiers in Bioengineering and Biotechnology, 2022 Costameres, as striated muscle-specific cell adhesions, anchor both M-lines and Z-lines of the sarcomeres to the extracellular matrix. Previous studies have demonstrated that costameres intimately participate in the initial assembly of myofibrils ...
Huaiyu Shi +8 more
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Scientific Reports, 2020 Muscles perform a wide range of motile functions in animals. Among various types are skeletal and cardiac muscles, which exhibit a steady auto-oscillation of force and length when they are activated at an intermediate level of contraction.
Fumiaki Kono +3 more
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Clinical Orthopaedics and Related Research, 2020 BACKGROUND Children with cerebral palsy have impaired muscle growth and muscular contractures that limit their ROM. Contractures have a decreased number of serial sarcomeres and overstretched lengths, suggesting an association with a reduced ability to ...
S. Dayanidhi +3 more
semanticscholar +1 more source