Results 51 to 60 of about 30,048 (267)

Sarcomere lengths in wooden breast broiler chickens

Italian Journal of Animal Science, 2020
The present study aims to measure the sarcomere lengths in normal broiler muscles and in non-lesion sites of breast muscles focally affected by Wooden Breast (WB).
Francesca Soglia, Massimiliano Petracci, Eero Puolanne   +2 more
doaj   +1 more source

Combining Ultrafast Ultrasound and High-Density EMG to Assess Local Electromechanical Muscle Dynamics: A Feasibility Study

IEEE Access, 2021
Skeletal muscles generate force, enabling movement through a series of fast electro-mechanical activations coordinated by the central nervous system.
Rick Waasdorp, Winfred Mugge, Hendrik J. Vos, Jurriaan H. de Groot, Martin D. Verweij, Nico de Jong, Alfred C. Schouten, Verya Daeichin   +7 more
doaj   +1 more source

Molecular analysis of sarcomeric and non-sarcomeric genes in patients with hypertrophic cardiomyopathy [PDF]

Gene, 2016
Hypertrophic cardiomyopathy (HCM) is a common genetic heart disorder characterized by unexplained left ventricle hypertrophy associated with non-dilated ventricular chambers. Several genes encoding heart sarcomeric proteins have been associated to HCM, but a small proportion of HCM patients harbor alterations in other non-sarcomeric loci.
BOTTILLO, IRENE, D'ANGELANTONIO, DANIELA, CAPUTO, VIVIANA, PAIARDINI, ALESSANDRO, LIPARI, MARTINA, De Bernardo, C, Giannarelli, D, PIZZUTI, Antonio, Majore, S, Castori, M, Zachara, E, Re, F, GRAMMATICO, Paola   +12 more
openaire   +3 more sources

A transcriptomics resource reveals a transcriptional transition during ordered sarcomere morphogenesis in flight muscle

eLife, 2018
Muscles organise pseudo-crystalline arrays of actin, myosin and titin filaments to build force-producing sarcomeres. To study sarcomerogenesis, we have generated a transcriptomics resource of developing Drosophila flight muscles and identified 40 ...
Maria L Spletter, Christiane Barz, Assa Yeroslaviz, Xu Zhang, Sandra B Lemke, Adrien Bonnard, Erich Brunner, Giovanni Cardone, Konrad Basler, Bianca H Habermann, Frank Schnorrer   +10 more
doaj   +1 more source

Cardiomyopathy Mutations in the Tail of β-Cardiac Myosin Modify the Coiled-coil Structure and Affect Integration into Thick Filaments in Muscle Sarcomeres in Adult Cardiomyocytes*

Journal of Biological Chemistry, 2013
Background: It is unclear how mutations in the coiled-coil tail of β-cardiac myosin cause heart disease. Results: Effects of disease-causing mutations in the myosin tail were studied in vivo and in vitro. Conclusion: Mutations that reduce helical content
Marcin Wolny, M. Colegrave, L. Colman, E. White, P. Knight, M. Peckham   +5 more
semanticscholar   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Early Clinical, Imaging, and Pathological Characteristics of SRPK3/TTN‐Digenic Myopathy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective SRPK3/TTN‐digenic myopathy was recently established as a skeletal muscle myopathy caused by digenic inheritance. This study characterizes the early clinical presentation of SRPK3/TTN‐digenic myopathy in one previously reported and seven newly identified pediatric patients.
Rotem Orbach, Sandra Donkervoort, Carola Hedberg‐Oldfors, Giovanni Baranello, Dimah Saade, Precilla D'Souza, Ruchee Patel, Eva Michael, A. Reghan Foley, Diana Bharucha‐Goebel, S. Jin Haugland, Meghan McAnally, Omer Abdul Hamid, Katherine Chao, Ellen F. Macnamara, Alan H. Beggs, Anna Sarkozy, Juliane Mueller, Steven A. Moore, Richard S. Finkel, Cynthia J. Tifft, Francesco Muntoni, Anders Oldfors, Carsten G. Bönnemann   +23 more
wiley   +1 more source

Molecular-scale visualization of sarcomere contraction within native cardiomyocytes

Nature Communications, 2021
Sarcomeres, the building blocks of striated muscles, comprise ordered actomyosin arrays involved in force production. Here, the authors visualize sarcomere organization in neonatal cardiomyocytes with in situ cryo-electron tomography, revealing a reduced
Laura Burbaum, Jonathan Schneider, Sarah Scholze, Ralph T. Böttcher, Wolfgang Baumeister, Petra Schwille, Jürgen M. Plitzko, Marion Jasnin   +7 more
doaj   +1 more source

Light‐Assisted 3D Printing Techniques and Photocrosslinking Strategies: Recent Advances in Musculoskeletal Tissue Engineering

Advanced Engineering Materials, EarlyView.
In this review, the current state of light‐assisted 3D printing as it pertains to engineering musculoskeletal tissues including bone, cartilage, skeletal muscle, tendon, and ligaments is summarized. Common printing techniques, photoreactive materials, and study design choices are compiled and reviewed.
Meagan Morgan, Bin Zhang, Roger Narayan
wiley   +1 more source

Targets for therapy in sarcomeric cardiomyopathies [PDF]

Cardiovascular Research, 2015
To date, no compounds or interventions exist that treat or prevent sarcomeric cardiomyopathies. Established therapies currently improve the outcome, but novel therapies may be able to more fundamentally affect the disease process and course. Investigations of the pathomechanisms are generating molecular insights that can be useful for the design of ...
Tardiff JC, Carrier L, Bers DM, POGGESI, CORRADO, FERRANTINI, CECILIA, COPPINI, RAFFAELE, Maier LS, Ashrafian H, Huke S, van der Velden J.   +9 more
openaire   +6 more sources