Results 51 to 60 of about 129,284 (273)

Model for End‐Stage Liver Disease/Pediatric End‐Stage Liver Disease exception policy and outcomes in pediatric patients with hepatopulmonary syndrome requiring liver transplantation

Liver Transplantation, EarlyView., 2022
Abstract Hepatopulmonary syndrome (HPS) is associated with increased waitlist mortality in liver transplantation (LT) candidates. Children with HPS are granted Model for End‐Stage Liver Disease (MELD)/Pediatric End‐Stage Liver Disease (PELD) exception points for waitlist prioritization in the United States based on criterion developed for adults.
Muhammad H. Raza, Yong Kwon, Pierre Kobierski, Asish C. Misra, Angelina Lim, Cameron Goldbeck, Kambiz Etesami, Rohit Kohli, Juliet Emamaullee   +8 more
wiley   +1 more source

Differences in Insulin-Like Growth Factor-1 and Tumor Necrosis Factor-Α Serum Levels on Various Degree of Sarcopenia in Elderly Patients: A Cross-Sectional Study

Jurnal Penyakit Dalam Indonesia, 2023
Introduction. Sarcopenia is a phenomenon of progressive decline in muscle function that occurs due to the aging process. Insulin-like growth factor-1 (IGF-1) and tumor necrosis factor-α (TNF-α) have an important role in the occurrence of sarcopenia ...
Auliangi Tamayo, Roza Mulyana, Rose Dinda Martini   +2 more
doaj   +1 more source

C57BL/6 life span study: age-related declines in muscle power production and contractile velocity [PDF]

, 2015
Quantification of key outcome measures in animal models of aging is an important step preceding intervention testing. One such measurement, skeletal muscle power generation (force * velocity), is critical for dynamic movement.
Graber, Ted G., Grange, Robert W., Kim, Jong-Hee, McLoon, Linda K., Thompson, LaDora V.   +4 more
core   +2 more sources

Atrophic Skeletal Muscle‐Derived Extracellular Vesicles Transfer miR‐125a‐5p to Inhibit Bone Formation in Osteoporosis during Aging

Advanced Science, EarlyView.
A muscle‐bone endocrine pathway in aging is revealed in which extracellular vesicles released from atrophic skeletal muscle (Aged‐SKM‐EVs) inhibit bone formation. These EVs deliver miR‐125a‐5p to osteoblasts, thereby suppressing the SIRT7‐Sp7 signaling axis and osteogenic differentiation.
Xiaoyan Shao, Pan Zhang, Zhidan Fan, Jiaquan Lin, Xiang Chen, Na Liu, Wang Gong, Yi He, Yining Zhou, Tianshu Shi, Yong Shi, Yuze Ma, Wentian Gao, Haosheng Wang, Depeng Fang, Chengzhi Wang, Wenshu Wu, Wenjin Yan, Jianghui Qin, Dongyang Chen, Haiguo Yu, Qing Jiang, Baosheng Guo   +22 more
wiley   +1 more source

Sarcopenia risk and associated factors among Chinese community-dwelling older adults living alone

Scientific Reports, 2021
Sarcopenia, defined as a progressive loss of muscle mass and reduced muscle strength and functional capacity, is common among older adults. This study aimed to assess the proportion of people at risk of sarcopenia and probable sarcopenia among Chinese ...
Li Cheng, Janet W. H. Sit, Helen Y. L. Chan, Kai Chow Choi, Regina K. Y. Cheung, Martin M. H. Wong, Francis Y. K. Li, Tin Yan Lee, Elina S. M. Fung, Keen Man Tai, Winnie K. W. So   +10 more
doaj   +1 more source

Diabetes Mellitus Facilitates Gallstone Formation Through CXCR2‐NETs–Mediated Liver‐Bile Barrier Damage

Advanced Science, EarlyView.
Diabetes is an independent risk factor for gallstones. It upregulates CXCR2 expression in hepatic neutrophils, stimulating the formation of NETs that disrupt hepatocellular tight junctions and the liver‐bile barrier. NETs enter bile to accelerate gallstone development, while sarcosine inhibits CXCR2 and NETs production, effectively reducing diabetes ...
Chao Shi, Shuo Feng, Tianming Liu, Ziang Meng, Yi Zheng, Zhenghao Huang, Tong Wang, Bojian Zhang, Dongbo Xue, Biao Ma, Xianzhi Meng   +10 more
wiley   +1 more source

Prevalence of sarcopenia and sarcopenic obesity in Korean adults: The Korean Sarcopenic Obesity Study (KSOS) [PDF]

, 2009
*Context:* Sarcopenic obesity (SO), a combination of excess weight and reduced muscle mass and/or strength, is suggested to be associated with an increased risk of adverse health outcomes.
Dong Seop Choi, Hye Jin Yoo, Hyun Joo Kang, Ji A Seo, Kang Il Lim, Kyung Mook Choi, Nan Hee Kim, Sae Jeong Yang, Sei Hyun Baik, Sin Gon Kim, Tae Nyun Kim, Wook Song   +11 more
core   +1 more source

Examining evidence based resistance plus balance training in community-dwelling older adults with complex health care needs: Trial protocol for the Muscling Up Against Disability project [PDF]

, 2017
Available online 6 October 2016Abstract not availableJustin W.L.
Gardiner, Paul, Henwood, Tim, Hodgkinson, Brent, Keogh, Justin W L, Rouse, Kevin, Tuckett, Anthony   +5 more
core   +2 more sources

The Age‐Dependent Resident Myonuclear Multi‐Omic Response to an Acute Skeletal Muscle Hypertrophic Stimulus in Mice

Advanced Science, EarlyView.
Resident myonuclei are the molecular “control centers” for large multinuclear muscle fibers. It is presumed that, with aging, these control centers become compromised and contribute to delayed or blunted muscle adaptive potential. This study is a detailed roadmap that exposes how young versus aged myonuclei respond to a hypertrophic loading stimulus ...
Pieter J. Koopmans, Ronald G. Jones III, Ana Regina Cabrera, Francielly Morena, Nicholas P. Greene, John J. McCarthy, Ahmed Ismaeel, Yuan Wen, Kevin A. Murach   +8 more
wiley   +1 more source

Growing Older, Staying Strong: Preventing Sarcopenia Through Strength Training [PDF]

, 2003
Older people can reduce their frailty, become more mobile and stave off the muscle-wasting condition known as sarcopenia by working out as little as twice a ...
Michael J. Hewitt
core