Results 41 to 50 of about 54,168 (197)

Infestação por ácaros da espécie Chirodiscoides caviae em porquinho-da-Índia (Cavia porcellus)

open access: yesMedicina Veterinária, 2023
A espécie Cavia porcellus (Rodentia, Caviidae), conhecida popularmente como cobaia ou porquinho-da-Índia, é um roedor utilizado como animal de laboratório e, devido ao seu tamanho e fácil adaptação, vem ganhando maior espaço nos lares brasileiros como ...
Rayssa Dourado Fontenele   +7 more
doaj   +4 more sources

Degradable glycopolymers for saRNA transfection

open access: yesPolymer Chemistry, 2023
Gene delivery is a powerful technique that is often exploited in the treatment of several diseases.
Alessandra Monaco   +4 more
openaire   +1 more source

A Superhydrophobic 3D Cell Culture System Reveals the Mechanobiological Role of Cancer‐Associated Fibroblasts in Prostate Cancer Metastasis

open access: yesAdvanced Healthcare Materials, EarlyView.
A superhydrophobic 3D cell culture platform enables rapid and consistent formation of heterotypic tumor–stroma clusters, and reveals how physiological shear conditions influence metastatic signaling. Mechanical stimulation of cancer‐associated fibroblasts promotes sustained cytokine secretion and survival‐promoting pathways, showing how multicellular ...
Alexandria T. Carter   +5 more
wiley   +1 more source

A Novel Self‐Amplifying mRNA with Decreased Cytotoxicity and Enhanced Protein Expression by Macrodomain Mutations

open access: yesAdvanced Science
The efficacy and safety of self‐amplifying mRNA (saRNA) have been demonstrated in COVID‐19 vaccine applications. Unlike conventional non‐replicating mRNA (nrmRNA), saRNA offers a key advantage: its self‐replication mechanism fosters efficient expression ...
Yue Gong   +5 more
doaj   +1 more source

Fatores de risco associados à ocorrência de sarna sarcóptica e prevalência em suínos nas fases de crescimento e terminação, na região Sul do Brasil [PDF]

open access: yesCiência Rural, 2003
Foi realizada uma pesquisa epidemiológica observacional em 64 rebanhos da região Sul do Brasil, com o objetivo de determinar a prevalência e identificar o conjunto de fatores de risco que melhor explicam a ocorrência de sarna sarcóptica em suínos nas ...
Doralice Pedroso-de- Paiva   +5 more
doaj   +1 more source

Evolutionary history of four binary blue stragglers from the globular clusters \omega Cen, M55, 47 Tuc and NGC 6752

open access: yes, 2016
Context. Origin and evolution of blue stragglers in globular clusters is still a matter of debate. Aims. The aim of the present investigation is to reproduce the evolutionary history of four binary blue stragglers in four different clusters, for which ...
Pamyatnykh, A. A.   +2 more
core   +1 more source

Determination of the basic parameters of the dwarf nova EY Cygni [PDF]

open access: yes, 2006
High-dispersion spectroscopy of EY Cyg obtained from data spanning twelve years show, for the first time, the radial velocity curves from both emission and absorption line systems, yielding semi-amplitudes K_{em}=24+/- 4 km s^-1 and K_{abs}=54+/- 2 km s^-
Beuermann   +34 more
core   +3 more sources

Enhanced Intracellular Stability and Translation Efficiency of mRNA Drugs by a 2‐arm mRNA Platform

open access: yesAdvanced Science, EarlyView.
We constructed a 2‐arm mRNA, characterized by a unique topology formed through the dimerization of two mRNA 3’ tails. The 2‐arm mRNA improves 3’ tail stability and resistance to nuclease degradation, resulting in an intracellular half‐life of up to 65 h. This method substantially enhances the translation capacity of mRNA drugs.
Xucong Teng   +5 more
wiley   +1 more source

Composite Accretion Disk and White Dwarf Photosphere Analyses of the FUSE and HST Observations of EY Cygni

open access: yes, 2004
We explore the origin of FUSE and HST STIS far UV spectra of the dwarf nova, EY Cyg, during its quiescence using \emph{combined} high gravity photosphere and accretion disk models as well as model accretion belts.
Boris T. Gänsicke   +11 more
core   +2 more sources

A hypothetical proposal for association between migraine and Meniere's disease. [PDF]

open access: yes, 2020
Meniere's disease (MD) is a chronic condition affecting the inner ear whose precise etiology is currently unknown. We propose the hypothesis that MD is a migraine-related phenomenon which may have implications for future treatment options for both ...
Abouzari, Mehdi   +3 more
core  

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