Results 41 to 50 of about 11,540 (164)

Impact of B18R-Encoding Messenger Ribonucleic Acid Co-Delivery on Neutralizing Antibody Production in Self-Amplifying Messenger Ribonucleic Acid Vaccines

open access: yesVaccines
Objectives: The COVID-19 pandemic has brought mRNA vaccines to the forefront due to their widespread use. In this study, we explored the potential advantages of the self-amplifying mRNA (saRNA) vaccine over conventional mRNA vaccines. Methods: Initially,
Yutao Wang   +4 more
doaj   +1 more source

Viscosity of concentrated mRNA solutions: Implications for downstream processing

open access: yesBiotechnology Progress, EarlyView.
Abstract Messenger RNA (mRNA) therapeutics can be used to protect against infectious disease and for the treatment of cancers and genetic disorders. In order to obtain the desired therapeutic dosage, it is necessary to concentrate the mRNA to levels where the viscosity of the mRNA solutions can become significant.
Amin Javidanbardan   +3 more
wiley   +1 more source

Avaliação de indutores de resistência para o controle da sarna da macieira (Venturia inaequalis Cke.) e da cercosporiose da beterraba (Cercospora beticola Sacc.) [PDF]

open access: yes, 2011
Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro de Ciências Agrárias, Programa de Pós-Graduação em Recursos Genéticos Vegetais, Florianópolis, 2011As doenças foliares podem causar importantes danos às plantas cultivadas, como a ...
Felipini, Ricardo Barbosa
core  

Degradable glycopolymers for saRNA transfection [PDF]

open access: yes, 2023
Gene delivery is a powerful technique that is often exploited in the treatment of several diseases. Currently, most gene vectors are expensive virus-based systems, which can trigger immune responses.
Becer, C. Remzi   +4 more
core   +1 more source

Engineering mRNA‐LNP Medicines for the Ageing Brain: Opportunities and Challenges for Neurodegenerative Diseases

open access: yesExploration, EarlyView.
This review highlights recent advances in engineering messenger RNA (mRNA)‐lipid nanoparticles (LNPs) to cross the ageing blood–brain barrier and target neurodegenerative diseases. It outlines design principles, delivery routes, and translational challenges, charting a roadmap towards clinical application of mRNA‐LNP therapeutics for neurodegenerative ...
Abdel Ali Belaidi   +5 more
wiley   +1 more source

Sarna Bovina [PDF]

open access: yes, 2013
Los ácaros de la Sarna Bovina son de distribución mundial. Las especies principales son Psoroptes bovis, que causa la sarna psoróptica, Sarcoptes scabiei var.
González Avila, Karla Alejandra
core  

Co‐expression of HSV‐1 ICP34.5 enhances the expression of gene delivered by self‐amplifying RNA and mitigates its immunogenicity

open access: yesFEBS Open Bio
Self‐amplifying RNA (saRNA) vectors have garnered significant attention for their potential in transient recombinant protein expression and vaccination strategies.
Xuemin Lu   +6 more
doaj   +1 more source

Precipitation shapes colour polymorphism in a widespread spider

open access: yesFunctional Ecology, EarlyView.
Read the free Plain Language Summary for this article on the Journal blog. Abstract Colour polymorphism, the presence of multiple colour variants within a population, is a common example of intraspecific phenotypic variation and has served as a model for studying drivers of diversity.
Fabian C. Salgado‐Roa   +2 more
wiley   +1 more source

Informe de brots de sarna a Catalunya (2015-2022*) [PDF]

open access: yes, 2023
Sarna; Brots; Infecció parasitàriaSarna; Brotes; Infección parasitariaScabies; Outbreak; Parasitic infectionL’objectiu del present informe es descriure les característiques epidemiològiques dels brots de sarna notificats els darrers 8 anys a Catalunya ...
Izquierdo, Conchita   +3 more
core   +1 more source

Cuttings, Combings, Fettlings and Flock: Gender and Australian Wool ‘Waste’, 1900–1950

open access: yesGender &History, EarlyView.
ABSTRACT As Australia's wool industry produced vast amounts of fine fleece from the nineteenth century, the wool processing and clothes manufacturing industries generated waste – products like cuttings, combings, fettlings and flock. Salvaged and then sold to waste merchants, these and other materials had a second life.
Lorinda Cramer
wiley   +1 more source

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