Results 121 to 130 of about 160,873 (310)

Asymmetric Synthesis of Saturated Hydroxy Fatty Acids and Fatty Acid Esters of Hydroxy Fatty Acids

European Journal of Organic Chemistry, 2019
The recent discovery of a novel class of endogenous lipids, named Fatty Acid esters of Hydroxy Fatty Acids (FAHFAs), that present antidiabetic and anti‐inflammatory activities, has attracted the interest on hydroxy fatty acids (HFAs) and their derivatives.
Olga G. Mountanea, Dimitris Limnios, Maroula G. Kokotou, Asimina Bourboula, George Kokotos   +4 more
openaire   +2 more sources

Hepatic mitochondrial dysfunction induced by fatty acids and ethanol

, 2012
Understanding the key aspects of the pathogenesis of alcoholic fatty liver disease particularly alterations to mitochondrial function remains to be resolved.
Patel, V., Gyamfi, D., Everitt, H.E., Clemens, D.L., Tewfik, I.   +4 more
core   +1 more source

A Humanized Anti‐gD Broadly Neutralizing Antibody Confers Complete Post‐Exposure Protection against Pseudorabies Virus

Advanced Science, EarlyView.
Pseudorabies virus (PRV), an emerging zoonotic α‐herpesvirus, causes life‐threatening human encephalitis. We identified a broad‐spectrum neutralizing antibody 6F7 targeting PRV gD. It blocks gD‐Nectin‐1 binding and membrane fusion, inhibiting replication across all PRV variants, representing a promising candidate for anti‐PRV therapy.
Yue Sun, Jianbo Liu, Shi‐Jia Xu, Meng‐Xin Wang, Hongliang Zhang, Yanhe Zhang, Zhi‐Jun Tian, Jin‐Mei Peng, Xin Yin, Tong‐Qing An, Xue‐Hui Cai, Yan‐Dong Tang   +11 more
wiley   +1 more source

Insulin response and changes in composition of non-esterified fatty acids in blood plasma of middle-aged men following isoenergetic fatty and carbohydrate breakfasts

, 2000
It was previously shown that a high plasma concentration of non-esterified fatty acids (NEFA) persisted after a fatty breakfast, but not after an isoenergetic carbohydrate breakfast, adversely affecting glucose tolerance.
Williams, NR, Freeman, MA, Fletcher, RJ, Carpenter, KLH, Frape, DL, Palmer, CR   +5 more
core  

SuFEx‐Enabled Reprogramming of Flavonoids for Selective α‐Glucosidase Covalent Inhibition

Advanced Science, EarlyView.
Selective inhibition of intestinal α‐glucosidase remains limited by poor enzyme specificity and off‐target metabolic effects. Here, SuFEx click chemistry is used to reprogram natural flavonoids into covalent inhibitors with enhanced α‐glucosidase selectivity and controlled reactivity. This strategy enables effective regulation of carbohydrate digestion
Fengyu Guo, Liwei Zhang, Minlong Wang, Yanjin Du, Tianyu Zhang, Hao Chen, Jiazeng Sun, Yang Yu, Zude He, Jie An, Xiaoxu Zhang, Weilin Lin, Fazheng Ren, Pengjie Wang, Ping Liu   +14 more
wiley   +1 more source

Unravelling the anti-inflammatory mechanisms of dietary fatty acids [PDF]

, 2009
Polyunsaturated fatty acids (PUFA) have been shown to modulate immune responses and have therapeutic effects in inflammatory disorders. The specific mechanisms of their actions have yet to be defined.
Dowling, Jennifer K.
core  

CEBPG‐Mediated Palmitic Acid Adaptation of Cancer‐Associated Fibroblasts Drives Metastasis of Oral Squamous Cell Carcinoma

Advanced Science, EarlyView.
This study reveals a metabolic signaling axis in the OSCC microenvironment where palmitic acid (PA) drives the activation of CAFs. PA uptake triggers CEBPG‐dependent epigenetic remodeling to upregulate ERN1 and TMBIM6, thereby mitigating ER stress. This adaptive program sustains CAF survival and the pro‐metastatic phenotype, establishing this pathway ...
Yiling Duan, Yitong Li, Yufei Wu, Xiao Yang, Rui Li, Hui Zhao, Zhengjun Shang   +6 more
wiley   +1 more source

Variation in Fatty Acids Composition Including Trans Fat in Different Brands of Potato Chips by GC-MS [PDF]

Pakistan Journal of Analytical & Environmental Chemistry, 2010
Twelve different brands of potato chips were analyzed for their fatty acid compositions with eminence on trans fatty acid (TFA) using GC-MS. Results of the present study showed that the dominant fatty acids were saturated fatty acids. Among the saturated
Aftab A. Kandhro, S. T. H. Sherazi, S. A. Mahesar, M. Younis Talpur, Yawar Latif   +4 more
doaj  

A New Atherogenic Effect of Saturated Fatty Acids

Physiological Research, 2013
There is increasing evidence that dietary saturated fatty acids (SAFA) have not only an indirect atherogenic effect due to increasing LDL-cholesterol concentration but also a direct effect by activating the inflammation process. This review summarizes several recent publications in this field.
openaire   +2 more sources

Correlations among saturated and unsaturated fatty acids.

, 2019
Correlations among saturated and unsaturated fatty acids.
Huiyun Liu (845957), Dongnan Hu (6686339), Lu You (2032141), Chutian Wang (6686333), Zengliang Zhou (6686336), Ling Zhang (18071), Shuqin Yu (6686330)   +6 more
core   +1 more source