Results 161 to 170 of about 140,853 (265)

Cancer Stem Cells Shift Metabolite Acetyl‐Coenzyme A to Abrogate the Differentiation of CD103+ T Cells

open access: yesAdvanced Science, Volume 13, Issue 8, 9 February 2026.
Lei et al. demonstrate that cancer stem cells (CSCs) play a pivotal role in impairing the differentiation of CD103+ T cells in patients with non‐small‐cell lung cancer. The key mechanism involves CSC‐derived acetyl‐CoA, which disrupts CD103+ T cell differentiation by sequentially inducing acetylation and ubiquitination of the Blimp‐1 protein. Targeting
Jiaxin Lei   +10 more
wiley   +1 more source

Quality Characteristics of Baranjski Kulen (PGI) Fermented Sausage from Three Pork Production Chains. [PDF]

open access: yesFoods
Kušec G   +5 more
europepmc   +1 more source

Closed‐Loop Monitoring of Pathogenic Bacteria with a Pt Single Atom@Quinone–Phenol Nanozymes‐Based Platform: Enables Accurate Pathogen Detection and Eradication

open access: yesAggregate, Volume 7, Issue 2, February 2026.
This work constructs a closed‐loop monitoring platform that innovatively integrates dual‐anchored Pt single‐atom nanozymes and magnetic enrichment. It enables flexible triple‐mode detection and on‐demand sterilization. A custom‐built smart portable device allows for simultaneous on‐site identification and eradication of pathogens, transforming passive ...
Lulu Cao   +13 more
wiley   +1 more source

Anti‐Neoplastic Effects of Coffee on Gastrointestinal Cancer as Influenced by the Dietary Background: A Cross‐Sectional Study Based on NHANES 2001–2018

open access: yesCancer Medicine, Volume 15, Issue 2, February 2026.
ABSTRACT Background Coffee consumption has been strongly associated with gastrointestinal cancers, but the relationship is controversial. This study seeks to assess their correlation under different dietary backgrounds considering the substantial impact of the food matrix on the effects of bioactive compounds in coffee.
Huan Zhang   +11 more
wiley   +1 more source

The impact of B‐cell reconstitution on mRNA vaccine responses in allogeneic stem cell transplant recipients

open access: yesClinical &Translational Immunology, Volume 15, Issue 2, 2026.
We characterised B‐cell responses to vaccination in allogeneic haematopoietic stem cell transplant (alloHCT) recipients. While mRNA prime‐boost vaccination stimulated expansion of vaccine‐specific B cells to affinity mature in a majority of alloHCT recipients, responses were variable and seemingly restricted by the presence of immature B‐cell ...
Fredrika Hellgren   +24 more
wiley   +1 more source

T‐cell exhaustion from a multiomics perspective: Differentiation mechanisms and regulatory networks in the journey from progenitor‐Exhausted T cells to terminally exhausted T cells

open access: yesClinical and Translational Medicine, Volume 16, Issue 2, February 2026.
(1) Core Process: Persistent antigen, from TDLNs to TME, drives Tpex → Tex‐int → Tex‐term differentiation. (2) Multiomics Regulation: This fate transition is orchestrated by a co‐ordinated, multi‐layered molecular network. (3) Functional Outcome: Dysregulated signalling and surging co‐inhibitory receptors lock in proliferative arrest and functional ...
Tong Zhu   +5 more
wiley   +1 more source

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