Results 51 to 60 of about 11,510 (261)

Gene expression and molecular evolution of sxtA4 in a saxitoxin producing dinoflagellate Alexandrium catenella [PDF]

, 2014
Copyright © 2014 Elsevier Ltd. All rights reserved. Dinoflagellates of the genus Alexandrium produce the neurotoxin saxitoxin (STX), responsible for paralytic shellfish poisoning (PSP) and accumulates in marine invertebrates. The recent identification of
Alvin, A, Murray, SA, Neilan, BA, Wiese, M   +3 more
core   +1 more source

Cardiac remodeling and arrhythmia in a mouse model of Depdc5 haploinsufficiency

Epilepsia, EarlyView.
Abstract Objective Some ion channel genes linked to developmental and epileptic encephalopathy (DEE) are also linked to cardiac arrhythmia, leading to the hypothesis that predisposition to cardiac arrhythmias may contribute to the complex disease presentation of DEE and possibly to the mechanism of sudden unexpected death in epilepsy.
Roberto Ramos‐Mondragon, Shuyun Wang, Qinghua Liu, Chunling Chen, Alexander M. Greiner, Abigail M. Marx, Maya Shih, Jack M. Parent, Barry London, Lori L. Isom   +9 more
wiley   +1 more source

Cyanopeptide Mixtures Induce Variable Synergistic and Antagonistic Effects Across Diverse Human Cell Lines

Environmental Toxicology, EarlyView.
ABSTRACT Cyanobacterial harmful algal blooms (cyanoHABs) threaten human, animal, and ecosystem health and safety through production of toxic secondary metabolites. Microcystis, a cosmopolitan bloom‐forming cyanobacterial genus, is well‐known for producing hepatotoxic microcystins (MCs), but it can produce many other bioactive cyanopeptides, such as ...
Lauren N. Hart, Katherine L. Lev, Sierra Hefferan, Sanduni H. Premathilaka, Sharmila I. Thenuwara, Dragan Isailovic, David H. Sherman, Gregory J. Dick   +7 more
wiley   +1 more source

Effects of Two Toxin-Producing Harmful Algae, Alexandrium catenella and Dinophysis acuminata (Dinophyceae), on Activity and Mortality of Larval Shellfish

Toxins, 2022
Harmful algal bloom (HAB) species Alexandrium catenella and Dinophysis acuminata are associated with paralytic shellfish poisoning (PSP) and diarrhetic shellfish poisoning (DSP) in humans, respectively.
Sarah K. D. Pease, Michael L. Brosnahan, Marta P. Sanderson, Juliette L. Smith   +3 more
doaj   +1 more source

Cancer pain: current practice and emerging targets

British Journal of Pharmacology, EarlyView.
Cancer pain (CP) arises from a complex interplay between the tumour and its microenvironment. Many patients experience a mixed pain phenotype that encompasses nociceptive, neuropathic and neuroinflammatory mechanisms, and vary across tumour type and disease stage. Despite decades of intensive research, the mainstay of cancer pain treatment is still non‐
Yi Ye, Marcin Chwistek, Zhiting Gong, Vanessa Uzonwanne, Xiaojie Shi, Arpad Szallasi   +5 more
wiley   +1 more source

An Electrochemical Ti₃C₂T_x Aptasensor for Sensitive and Label-Free Detection of Marine Biological Toxins

Sensors, 2021
Saxitoxin (STX) belongs to the family of marine biological toxins, which are major contaminants in seafood. The reference methods for STX detection are mouse bioassay and chromatographic analysis, which are time-consuming, high costs, and requirement of ...
Najeeb Ullah, Wei Chen, Beenish Noureen, Yulan Tian, Liping Du, Chunsheng Wu, Jie Ma   +6 more
doaj   +1 more source

Diversity of luciferase sequences and bioluminescence production in Baltic Sea Alexandrium ostenfeldii [PDF]

, 2016
The toxic dinoflagellate Alexandrium ostenfeldii is the only bioluminescent bloom-forming phytoplankton in coastal waters of the Baltic Sea. We analysed partial luciferase gene (lcf) sequences and bioluminescence production in Baltic A. ostenfeldii bloom
Kremp, Anke, Le Tortorec, Anniina H., Simis, Stefan G. H., Tahvanainen, Pia   +3 more
core   +2 more sources

Phytoplankton growth and potential cyanotoxin production differ in response to nitrogen and phosphorus amendments in late summer communities from Kabetogama Lake (Minnesota, United States)

Journal of Phycology, EarlyView.
Abstract Cyanotoxins such as microcystin (MC), cylindrospermopsin, and saxitoxin are secondary metabolites that are rich in nitrogen (N). Most cyanobacteria grow best on reduced inorganic N (ammonium, NH4), but when NH4 is absent, cyanobacteria can activate physiological pathways to process other N forms (e.g., nitrate; NO3).
James H. Larson, Ryan P. Maki, Sean W. Bailey, Victoria G. Christensen, Keith A. Loftin, Erin A. Stelzer, James C. Smith, Seth A. McWhorter   +7 more
wiley   +1 more source

Tetrodotoxin and Its Analogues in the Pufferfish Arothron hispidus and A. nigropunctatus from the Solomon Islands: A Comparison of Their Toxin Profiles with the Same Species from Okinawa, Japan

Toxins, 2015
Pufferfish poisoning has not been well documented in the South Pacific, although fish and other seafood are sources of protein in these island nations. In this study, tetrodotoxin (TTX) and its analogues in each organ of the pufferfish Arothron hispidus ...
Clyde Gorapava Puilingi, Yuta Kudo, Yuko Cho, Keiichi Konoki, Mari Yotsu-Yamashita   +4 more
doaj   +1 more source

Microcystis Sp. Co-Producing Microcystin and Saxitoxin from Songkhla Lake Basin, Thailand

Toxins, 2021
The Songkhla Lake Basin (SLB) located in Southern Thailand, has been increasingly polluted by urban and industrial wastewater, while the lake water has been intensively used. Here, we aimed to investigate cyanobacteria and cyanotoxins in the SLB.
Ampapan Naknaen, Waraporn Ratsameepakai, Oramas Suttinun, Yaowapa Sukpondma, Eakalak Khan, Rattanaruji Pomwised   +5 more
doaj   +1 more source