Results 51 to 60 of about 28,538 (210)
The FEBS Journal, EarlyView.We investigated the potential of iloperidone as an activator of Sigma‐1 receptor (S1R) neuroprotective function in juvenile Huntington's disease (jHD). We tested iloperidone on cortical neurons differentiated from patient‐derived iPSCs, demonstrating that it acts as a S1R agonist, decreasing apoptosis, huntingtin aggregation, and oxidative stress ...
Ersilia Fornetti +11 more
wiley +1 more source
Wikidata-Enhanced Authority Records: A Project for Personal Names in SBN
JLIS.itThe catalogue of the National Library Service (SBN), developed and expanded through cooperative cataloguing, has experienced exponential growth over time. Currently, the titles archive contains over 21 million records, while the authors archive includes
Elena Ravelli
doaj +1 more source
Retinoblastoma: Identifying the Diagnostic Signs for Early Treatment [PDF]
, 2015 Retinoblastoma is a rare but significant cause of childhood eye cancer world-wide. The prognosis depends upon early diagnosis and treatment but also upon accurate classification of the tumours.
Barratt, K. +4 more
core +2 more sources
Bone Grafts: Everything You Need to Know
Journal of Periodontal Research, EarlyView.This review classifies bone grafts (autograft, allograft, xenograft, synthetic) by source and osteogenic/inductive/conductive potential, linking material properties and mechanisms to clinical indications in periodontal and dental regeneration. Key challenges—limited osteoinduction, poor vascularisation, unbalanced resorption, handling difficulties, and
Håvard Jostein Haugen +5 more
wiley +1 more source
Hume, the Philosophy of Science and the Scientific Tradition [PDF]
, 2018 Although the main focus of Hume’s career was in the humanities, his work also has an observable role in the historical development of natural sciences after his time.
Slavov, Matias
core +2 more sources
Obesity Reviews, EarlyView.ABSTRACT Background/Aim We conducted a systematic review with network meta‐analyses (NMA) summarizing the effects and safety of lifestyle interventions containing nutrition (NUT; e.g., calorie restriction), exercise (EX; e.g., aerobic/resistance exercise) and behavior change interventions (BCI; e.g., behavioral therapy) on physical function, body ...
Gabriel Torbahn +12 more
wiley +1 more source
Frontiers in Plant Science, 2016 Number of spikelets per panicle (NSP) is a key trait to increase yield potential in rice (O. sativa). The architecture of the rice inflorescence which is mainly determined by the length and number of primary (PBL and PBN) and secondary (SBL and SBN ...
Maria Camila Rebolledo +7 more
doaj +1 more source
Structural Variations Contribute to Subspeciation and Yield Heterosis in Rice
Plant Biotechnology Journal, EarlyView.ABSTRACT Yield heterosis has been extensively exploited in hybrid breeding, with intersubspecific hybrids often exhibiting the most pronounced effects. However, developing elite hybrids remains a laborious and time‐consuming process. The genetic basis of heterosis has been debated for over a century, hindered largely by the lack of high‐quality genomes.
Zhiwu Dan, Yunping Chen, Wenchao Huang
wiley +1 more source
Molecules, 2019 Silybin (SBN) is a major active constituent of silymarin, a mixture of flavonoids found in fruits and seeds of milk thistle. The aim of this study was to describe a simple bioanalytical method for quantifying SBN in rat plasma.
Eun-Sol Ha +7 more
doaj +1 more source
El escepticismo en el pensamiento político e histórico de David Hume [PDF]
, 2018 This essay argues that Hume’s political and historical thought is well read as skeptical and skeptical in a way that roots it deeply in the Hellenistic traditions of both Pyrrhonian and Academical thought. It deploys skeptical instruments to undermine
Fosl, Peter S.
core