Results 101 to 110 of about 723,869 (275)

Rethinking plastic waste: innovations in enzymatic breakdown of oil‐based polyesters and bioplastics

open access: yesFEBS Open Bio, EarlyView.
Plastic pollution remains a critical environmental challenge, and current mechanical and chemical recycling methods are insufficient to achieve a fully circular economy. This review highlights recent breakthroughs in the enzymatic depolymerization of both oil‐derived polyesters and bioplastics, including high‐throughput protein engineering, de novo ...
Elena Rosini   +2 more
wiley   +1 more source

Bionic Nanostructures Create Mechanical Signals to Mediate the Composite Structural Bone Regeneration Through Multi‐System Regulation

open access: yesAdvanced Science
Regenerating bone defects has long been recognized as a significant clinical challenge. Drawing inspiration from the structure and properties of natural bone, bionic nanomaterials have emerged as a focal point in the field of bone tissue engineering ...
Yangfan Pei   +11 more
doaj   +1 more source

Pioglitazone plus (−)‐epigallocatechin gallate: a novel approach to enhance osteogenic performance in aged bone marrow mesenchymal stem cells

open access: yesFEBS Open Bio, EarlyView.
Aged human bmMSCs are seeded in the scaffold. Osteoblastic induction can slightly increase cell's bone‐forming activity to produce bone‐like tissues, shown as the sporadic xylenol orange‐stained spots (the lower left image). Notably, pioglitazone plus EGCG co‐treatment dramatically increases cell's bone‐forming activity and bone‐like tissue production (
Ching‐Yun Chen   +6 more
wiley   +1 more source

A Vibrio cholerae viral satellite maximizes its spread and inhibits phage by remodeling hijacked phage coat proteins into small capsids

open access: yeseLife
Phage satellites commonly remodel capsids they hijack from the phages they parasitize, but only a few mechanisms regulating the change in capsid size have been reported.
Caroline M Boyd   +4 more
doaj   +1 more source

Novel Application Method for Mesenchymal Stem Cell Therapy Utilizing Its Attractant-Responsive Accumulation Property

open access: yesApplied Sciences, 2019
Stem cell therapy is an emerging treatment modality for various diseases. Because mesenchymal stem cells (MSCs) are known to accumulate at the site of damage, their possible clinical application has been investigated.
Nobuyuki Ueda   +10 more
doaj   +1 more source

Nuclear pore links Fob1‐dependent rDNA damage relocation to lifespan control

open access: yesFEBS Open Bio, EarlyView.
Damaged rDNA accumulates at a specific perinuclear interface that couples nucleolar escape with nuclear envelope association. Nuclear pores at this site help inhibit Fob1‐induced rDNA instability. This spatial organization of damage handling supports a functional link between nuclear architecture, rDNA stability, and replicative lifespan in yeast.
Yamato Okada   +5 more
wiley   +1 more source

Clinical Outcomes of Biomaterial Scaffolds in Regenerative Endodontic Therapy: A Systematic Review and Meta-analysis

open access: yesEuropean Endodontic Journal
Blood clot, platelet-rich fibrin, and plasma-rich plasma are the three most commonly used scaffolds in regenerative endodontic therapy. The current study aimed to evaluate the clinical outcomes of plasma-rich plasma (PRP) and platelet-rich fibrin (PRF ...
Hossein Shahoon   +5 more
doaj   +1 more source

Matrix metalloproteinase‐9 regulates cell adhesion and membrane protrusive activity of ovarian cancer cells

open access: yesFEBS Open Bio, EarlyView.
Matrix metalloproteinase‐9 (MMP9) drives ovarian cancer progression. Using MMP9‐null cells (M9‐KO) created from ovarian cancer cells, we found MMP9 loss did not block Epidermal Growth Factor (EGF)‐driven E‐cadherin dissolution or EMT but delayed and reduced EGF‐driven membrane protrusions. Transient MMP9 re‐expression drove membrane protrusion.
Claire Strauel   +8 more
wiley   +1 more source

Scaffolding

open access: yes, 2019
Scaffolding as a metaphor in teaching and learning describes the adaptive and temporary support provided by a more competent person (e.g., teacher or adult) to a less competent person (e.g., student or child). Scaffolding, with its link to Vygotskian sociocultural theory, has been popularized and applied to a number of education realms.
Austin Volz   +2 more
openaire   +3 more sources

Functionally gradient tissue scaffold design and deposition path planning for bio-additive processes [PDF]

open access: yes, 2013
A layer-based tissue scaffold is designed with heterogeneous internal architecture. The proposed layer-based design uses a bi-layer pattern of radial and spiral layer consecutively to generate functionally gradient porosity following the geometry of the ...
Khoda, AKM Bashirul   +2 more
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