Results 91 to 100 of about 512,987 (302)

Biocompatibility Issue Of Tissue Engineered Heart Valves

open access: yesArchives of Metallurgy and Materials, 2015
Tissue engineering is a new field of knowledge which creates the possibilities for producing bioactive cardiac prostheses that will characterize by biomechanical and morphological properties similar to native tissue.
Wilczek P.
doaj   +1 more source

Epigenetic silencing of the liver‐specific lncRNA LUNAR promotes liver cancer progression via NOTCH activation

open access: yesMolecular Oncology, EarlyView.
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang   +9 more
wiley   +1 more source

A Small Molecule Scaffold Analysis: Biological Profiles of Novel, Privileged, and Promiscuous Scaffolds [PDF]

open access: yes, 2013
Owing to the better understanding of physiochemical and biological challenges associated with the bioactivity of small organic molecules, novel scaffolds are becoming more extensively engineered and more highly optimized.
Hammad, Layal
core  

Scaffold-Enforced Nanoscale Crystalline Order Supersedes Interfacial Interactions in Driving CsPbI3 Perovskite Phase Stability

open access: yes, 2022
The equilibrium phase of cesium lead iodide (CsPbI3) is a high-density, low-symmetry, yellow crystalline solid below 320 °C, above which it transitions to the optoelectronically functional, black, perovskite phase.
Benjamin M. Lefler (9089215)   +2 more
core   +1 more source

Influence of Structure–Property Relationships of Polymeric Biomaterials for Engineering Multicellular Spheroids

open access: yesBioengineering
Two-dimensional cell culture systems lack the ability to replicate the complex, three-dimensional (3D) architecture and cellular microenvironments found in vivo.
Sheetal Chowdhury, Amol V. Janorkar
doaj   +1 more source

3D Cardiac Cell Culture: A Critical Review of Current Technologies and Applications

open access: yesFrontiers in Cardiovascular Medicine, 2019
Three-dimensional (3D) cell culture is often mentioned in the context of regenerative medicine, for example, for the replacement of ischemic myocardium with tissue-engineered muscle constructs.
Christian Zuppinger
doaj   +1 more source

PANoptosis in the pathogenesis of myelodysplastic syndromes

open access: yesMolecular Oncology, EarlyView.
PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla   +4 more
wiley   +1 more source

Response to Article “Oriented Graphene Oxide Scaffold Promotes Nerve Regeneration in vitro and in vivo” [Letter]

open access: yesInternational Journal of Nanomedicine
Novrynda Eko Satriawan,1,* Ariyani Noviantari1,2,* 1Doctoral Program in Biomedical Science, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; 2Center for Biomedical Research, Research Organization for Health, National Research and ...
Satriawan NE, Noviantari A
doaj  

Biliary Injuries Repair Using Copolymeric Scaffold: A Systematic Review and In Vivo Experimental Study

open access: yesJournal of Functional Biomaterials
Background: Common bile duct (CBD) treatments are often associated with complications, limiting long-term efficacy. To overcome these issues, polymeric grafts have been suggested as promising alternatives, since they are highly customizable ...
Salvatore Buscemi   +9 more
doaj   +1 more source

Somatostatin receptor 4 (SSTR4) is a tumor suppressor in cutaneous and head & neck squamous cell carcinomas

open access: yesMolecular Oncology, EarlyView.
This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi   +6 more
wiley   +1 more source

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