Results 111 to 120 of about 954,074 (407)
Mathematical modelling of tissue-engineering angiogenesis [PDF]
, 2009 We present a mathematical model for the vascularisation of a porous scaffold following implantation in vivo. The model is given as a set of coupled non-linear ordinary differential equations (ODEs) which describe the evolution in time of the amounts of ...
Buttery, Lee D +6 more
core
Advanced Science, 2021 Combinational therapy is used for a long time in cancer treatment to overcome drug resistance related to monotherapy. Increased pharmacological data and the rapid development of deep learning methods have enabled the construction of models to predict and
Zhaofeng Ye +4 more
doaj +1 more source
arXiv: General Physics, 2019 The mathematical foundations of relativistic quantum mechanics is largely based upon the discovery of the Pauli and Dirac matrices. An algebra which lies at an even more fundamental level is the geometric Clifford algebra with metric signature (2,3)=(++---).
openaire +3 more sources
Molecular Oncology, Volume 19, Issue 5, Page 1371-1385, May 2025.Patient‐derived xenografts (PDXs) can be improved by implantation of a humanized niche. We tested different biomaterials and approaches, and demonstrate that the combination of an injectable biomaterial for scaffold creation plus an intravenous route for acute myeloid leukemia (AML) xenotransplantation provide the most convenient and robust approach to
Daniel Busa +13 more
wiley +1 more source
Development of the early axon scaffold in the rostral brain of the small spotted cat shark (Scyliorhinus canicula) embryo [PDF]
, 2014 International audienceThe cat shark is increasingly used as a model for Chondrichthyes, an evolutionarily important sister group of the bony vertebrates that include teleosts and tetrapods.
Schubert, Frank +2 more
core +3 more sources
Transcriptome‐wide analysis of circRNA and RBP profiles and their molecular relevance for GBM
Molecular Oncology, EarlyView.CircRNAs are differentially expressed in glioblastoma primary tumors and might serve as therapeutic targets and diagnostic markers. The investigation of circRNA and RNA‐binding proteins (RBPs) interactions shows that distinct RBPs play a role in circRNA biogenesis and function.
Julia Latowska‐Łysiak +14 more
wiley +1 more source
Evolutionary and molecular foundations of multiple contemporary functions of the nitroreductase superfamily. [PDF]
, 2017 Insight regarding how diverse enzymatic functions and reactions have evolved from ancestral scaffolds is fundamental to understanding chemical and evolutionary biology, and for the exploitation of enzymes for biotechnology.
Akiva, Eyal +3 more
core +1 more source
Molecular Oncology, EarlyView.We identified adaptor protein ShcD as upregulated in triple‐negative breast cancer and found its expression to be correlated with reduced patient survival and increased invasion in cell models. Using a proteomic screen, we identified novel ShcD binding partners involved in EGFR signaling pathways.
Hayley R. Lau +11 more
wiley +1 more source
Porcine bone scaffolds adsorb growth factors secreted by MSCs and improve bone tissue repair [PDF]
, 2017 An ideal tissue-engineered bone graft should have both excellent pro-osteogenesis and pro-angiogenesis properties to rapidly realize the bone regeneration in vivo . To meet this goal, in this work a porcine bone scaffold was successfully used as a Trojan
Bressan, Eriberto +6 more
core +2 more sources
Somatosensory scaffolding structures [PDF]
Frontiers in Molecular Neuroscience, 2012 Dynamic changes in somatosensory perception occur as a result of multiple signaling events. In many instances, over-activation of sensory receptors results in the desensitization and subsequent increased threshold for activation of receptors. In other cases, receptor sensitization can occur following tissue injury and/or inflammation.
openaire +4 more sources