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Osteoimmunity‐Regulating Biomimetically Hierarchical Scaffold for Augmented Bone Regeneration
Advances in Materials, 2022Engineering a proper immune response following biomaterial implantation is essential to bone tissue regeneration. Herein, a biomimetically hierarchical scaffold composed of deferoxamine@poly(ε‐caprolactone) nanoparticles (DFO@PCL NPs), manganese carbonyl
Jin Zhang +10 more
semanticscholar +1 more source
Materials Science and Engineering C: Materials for Biological Applications, 2021
Bone injuries and fractures generally take a long period to heal itself. To address this problem, bone tissue engineering (BTE) has gained significant research impetus.
S. Gautam +7 more
semanticscholar +1 more source
Bone injuries and fractures generally take a long period to heal itself. To address this problem, bone tissue engineering (BTE) has gained significant research impetus.
S. Gautam +7 more
semanticscholar +1 more source
Proceedings of the 19th ACM Conference on Computer-Supported Cooperative Work & Social Computing, 2016
The development of strong social and emotional skills is central to personal wellbeing. Increasingly, these skills are being taught in schools through well researched curricula. Such social-emotional learning (SEL) curricula are most effective if reinforced by parents, thus transferring the skills into everyday contexts.
Petr Slovák +7 more
openaire +1 more source
The development of strong social and emotional skills is central to personal wellbeing. Increasingly, these skills are being taught in schools through well researched curricula. Such social-emotional learning (SEL) curricula are most effective if reinforced by parents, thus transferring the skills into everyday contexts.
Petr Slovák +7 more
openaire +1 more source
Journal of Knee Surgery, 2014
There are two scaffold products designed for meniscal reconstruction or substitution of partial meniscal defects that are currently available in the Europe: the collagen meniscal implant (CMI; Ivy Sports Medicine, Gräfelfing, Germany) and the polymer scaffold (PS; Actifit, Orteq Bioengineering, London, United Kingdom). The CMI has demonstrated improved
Kevin R, Myers +2 more
openaire +2 more sources
There are two scaffold products designed for meniscal reconstruction or substitution of partial meniscal defects that are currently available in the Europe: the collagen meniscal implant (CMI; Ivy Sports Medicine, Gräfelfing, Germany) and the polymer scaffold (PS; Actifit, Orteq Bioengineering, London, United Kingdom). The CMI has demonstrated improved
Kevin R, Myers +2 more
openaire +2 more sources
Drug Discovery Today: Technologies, 2004
The aim of scaffold hopping is to discover structurally novel compounds starting from known active compounds by modifying the central core structure of the molecule. Scaffold hopping is a central task of modern medicinal chemistry requiring a multitude of techniques, which are discussed in this article.
Hans-Joachim, Böhm +2 more
openaire +2 more sources
The aim of scaffold hopping is to discover structurally novel compounds starting from known active compounds by modifying the central core structure of the molecule. Scaffold hopping is a central task of modern medicinal chemistry requiring a multitude of techniques, which are discussed in this article.
Hans-Joachim, Böhm +2 more
openaire +2 more sources
Three-dimensional (3D) printed scaffold and material selection for bone repair.
Acta Biomaterialia, 2019Critical-sized bone defect repair remains a substantial challenge in clinical settings and requires bone grafts or bone substitute materials. However, existing biomaterials often do not meet the clinical requirements of structural support, osteoinductive
Lei Zhang +3 more
semanticscholar +1 more source
Indole: A privileged scaffold for the design of anti-cancer agents.
European journal of medicinal chemistry, 2019In general, heterocyclic compounds are a significant source of pharmacologically active compounds. Among them, the indole scaffold widely distributes in natural products and bioactive molecules including anti-cancer agents.
Yichao Wan +4 more
semanticscholar +1 more source
Theory in Biosciences, 2016
Descriptions and interpretations of the natural world are dominated by dichotomies such as organism vs. environment, nature vs. nurture, genetic vs. epigenetic, but in the last couple of decades strong dissatisfaction with those partitions has been repeatedly voiced and a number of alternative perspectives have been suggested, from perspectives such as
openaire +2 more sources
Descriptions and interpretations of the natural world are dominated by dichotomies such as organism vs. environment, nature vs. nurture, genetic vs. epigenetic, but in the last couple of decades strong dissatisfaction with those partitions has been repeatedly voiced and a number of alternative perspectives have been suggested, from perspectives such as
openaire +2 more sources
3D printed PCL/SrHA scaffold for enhanced bone regeneration
Chemical Engineering Journal, 2019Strontium-containing hydroxyapatite (SrHA) is a promising material for bone repair and bone replacement due to the similar inorganic components with natural bone.
Dinghua Liu +9 more
semanticscholar +1 more source