Results 101 to 110 of about 262,567 (228)

Effects of adaptive scaffolding on performance, cognitive load and engagement in game-based learning: a randomized controlled trial

open access: yesBMC Medical Education
Background While game-based learning has demonstrated positive outcomes for some learners, its efficacy remains variable. Adaptive scaffolding may improve performance and self-regulation during training by optimizing cognitive load. Informed by cognitive
Tjitske J. E. Faber   +5 more
doaj   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

From Cracked Polytopes to Fano Threefolds

open access: yes, 2019
We construct Fano threefolds with very ample anti-canonical bundle and Picard rank greater than one from cracked polytopes - polytopes whose intersection with a complete fan forms a set of unimodular polytopes - using Laurent inversion; a method ...
Prince, Thomas
core   +1 more source

Function‐driven design of a surrogate interleukin‐2 receptor ligand

open access: yesFEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang   +9 more
wiley   +1 more source

Scaffolding

open access: yes, 2019
Scaffolding as a metaphor in teaching and learning describes the adaptive and temporary support provided by a more competent person (e.g., teacher or adult) to a less competent person (e.g., student or child). Scaffolding, with its link to Vygotskian sociocultural theory, has been popularized and applied to a number of education realms.
Austin Volz   +2 more
openaire   +3 more sources

The newfound relationship between extrachromosomal DNAs and excised signal circles

open access: yesFEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

A Sociocultural Perspective on the Impact of Instructor Versus Peer Scaffolding Upon Lexical Digesting and Reading Perception

open access: yesSAGE Open
Based on a sociocultural theory and a plethora of experiential studies on the efficacy of scaffolding on foreign language learning, the goal of this research article is to examine the effectiveness of diverse types of scaffolding on university students ...
Mohammad Awad Al-Dawoody Abdulaal   +4 more
doaj   +1 more source

Inviting Small Children to Dialogue – Scaffolding and Challenging Conversational Skills

open access: yesEducare, 2014
The purpose of this study was to learn about how to scaffold and challenge conversational skills in children at an early stage in language development.
Barbro Bruce
doaj   +1 more source

Scaffolding in Assisted Instruction [PDF]

open access: yes
On-The-Job Training, developed as direct instruction, is one of the earliest forms of training. This method is still widely in use today because it requires only a person who knows how to do the task, and the tools the person uses to do the task.
Gabriel ZAMFIR
core  

Scaffolding Strategy In Mathematics Learning [PDF]

open access: yes, 2011
Mathematics learning should be designed so that it is oriented to the goal which is focused on process. Learning orientation is focused on the development of ‘mathematical thinking’ and ‘mathematical disposition’.
Tedy , Machmud
core  

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