Results 121 to 130 of about 262,567 (228)
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source
Dwell time of a Brownian interacting molecule in a cellular microdomain [PDF]
The time spent by an interacting Brownian molecule inside a bounded microdomain has many applications in cellular biology, because the number of bounds is a quantitative signal, which can initiate a cascade of chemical reactions and thus has ...
Holcman, David, Taflia, Adi
core
Structural biology of ferritin nanocages
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley +1 more source
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
Developing language-aware teaching materials is increasingly recognized as essential for enhancing both language proficiency and content acquisition in diverse classroom settings.
Michael Morawski, Panagiota Georgakaki
doaj +1 more source
Mechanisms of IgE‐mediated food allergy and the role of allergen‐specific B cells
Food allergy arises when allergen‐specific B cells preferentially produce immunoglobulin E (IgE) antibodies against harmless foods. This article explains the mechanisms driving IgE‐mediated reactions, highlights the central role of these B cells, and discusses how natural tolerance (NT) and oral immunotherapy (OIT) can reshape allergic immune responses.
Juan‐Felipe López +2 more
wiley +1 more source
A necessidade de escolher, definir ou planejar questões relativas ao futuro é cultural- mente relacionada à juventude. Jovens das periferias transitam entre restrições epossibilidades, e essas transições devem ser consideradas como parte do processo de ...
Ayla Arapiraca-Galvão +1 more
doaj +1 more source
'Scaffolding': learning in the classroom
Recent interest in talk and learning in the classroom has encouraged a new metaphorical use for the term 'scaffolding'. This term is increasingly used to describe certain kinds of support which learners receive in their interaction with parents, teachers
Maybin, Janet +2 more
core
Stability analysis on different type of steel scaffolds [PDF]
During the lifetime of a building, the highest risk is in the construction phase. The collapse of scaffolding systems occurs quite often with considerable accidents reported.
Guillamón Causi, Pau
core
Tau acetylation at K331 has limited impact on tau pathology in vivo
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source

