Results 121 to 130 of about 262,567 (228)

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Dwell time of a Brownian interacting molecule in a cellular microdomain [PDF]

open access: yes, 2006
The time spent by an interacting Brownian molecule inside a bounded microdomain has many applications in cellular biology, because the number of bounds is a quantitative signal, which can initiate a cascade of chemical reactions and thus has ...
Holcman, David, Taflia, Adi
core  

Structural biology of ferritin nanocages

open access: yesFEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Exploring Student Perspectives and Practices with Language-Aware Materials in Geography Education: An Exploratory Case Study in a German High School Classroom

open access: yesEuropean Journal of Geography
Developing language-aware teaching materials is increasingly recognized as essential for enhancing both language proficiency and content acquisition in diverse classroom settings.
Michael Morawski, Panagiota Georgakaki
doaj   +1 more source

Mechanisms of IgE‐mediated food allergy and the role of allergen‐specific B cells

open access: yesFEBS Letters, EarlyView.
Food allergy arises when allergen‐specific B cells preferentially produce immunoglobulin E (IgE) antibodies against harmless foods. This article explains the mechanisms driving IgE‐mediated reactions, highlights the central role of these B cells, and discusses how natural tolerance (NT) and oral immunotherapy (OIT) can reshape allergic immune responses.
Juan‐Felipe López   +2 more
wiley   +1 more source

Scaffolding — Aportes para a Construção e Sustentação de Projetos de Vida de Jovens em Contexto Periférico

open access: yesRevista CS
A necessidade de escolher, definir ou planejar questões relativas ao futuro é cultural- mente relacionada à juventude. Jovens das periferias transitam entre restrições epossibilidades, e essas transições devem ser consideradas como parte do processo de ...
Ayla Arapiraca-Galvão   +1 more
doaj   +1 more source

'Scaffolding': learning in the classroom

open access: yes, 1992
Recent interest in talk and learning in the classroom has encouraged a new metaphorical use for the term 'scaffolding'. This term is increasingly used to describe certain kinds of support which learners receive in their interaction with parents, teachers
Maybin, Janet   +2 more
core  

Stability analysis on different type of steel scaffolds [PDF]

open access: yes, 2012
During the lifetime of a building, the highest risk is in the construction phase. The collapse of scaffolding systems occurs quite often with considerable accidents reported.
Guillamón Causi, Pau
core  

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

Home - About - Disclaimer - Privacy