Results 81 to 90 of about 373,160 (277)
Organoids in pediatric cancer research
FEBS Letters, EarlyView.Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley +1 more source
Reciprocal control of viral infection and phosphoinositide dynamics
FEBS Letters, EarlyView.Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley +1 more source
Children's interactions with interactive toy technology [PDF]
, 2003 Digital toys offer the opportunity to explore software scaffolding through tangible interfaces that are not bound to the desktop computer. This paper describes the empirical work completed by the CACHET (Computers and Children's Electronic Toys) project ...
Airey, S. +3 more
core +2 more sources
FEBS Letters, EarlyView.Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho +3 more
wiley +1 more source
The Influence of Causal Thinking with Scaffolding Type 2A and 2B on Optics Problem-Solving Ability
Jurnal Pendidikan Fisika Indonesia, 2018 The effectiveness of learning is affected by the assistance stages (scaffolding) provided. For example, the scaffolding of type 2a and type 2b supports the causal-thinking approach in learning.
N. Nurmadiah, J. Rokhmat, S. Ayub
doaj +1 more source
PMRI and Metacognitive Scaffolding [PDF]
, 2011 PMRI (Pendidikan Matematika Realistik Indonesia) has been implemented in some Primary Schools in Indonesia since 2001. Sanata Dharma University (USD) in Yogyakarta is one of the four universities which founded the PMRI Movement. Sanata Dharma University
Yansen., Marpaung
core
By dawn or dusk—how circadian timing rewrites bacterial infection outcomes
FEBS Letters, EarlyView.The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo +2 more
wiley +1 more source
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
FEBS Letters, EarlyView.This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
EXPLORING EFL TEACHER’S SCAFFOLDING STRATEGIES IN WRITING SKILL AT MTS AL WASHLIYAH CIREBON (QUALITATIVE RESEARCH) [PDF]
, 2016 Devi Risnawati. 14121330384. Exploring EFL Teacher’s Scaffolding Strategies in Writing Skill at Mts Al Washliyah Cirebon (Qualitative Research). Writing is among the most important skills that foreign language students need to develop, and the ability
Devi Risnawati,
core +1 more source
Peptide‐based ligand antagonists block a Vibrio cholerae adhesin
FEBS Letters, EarlyView.The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang +9 more
wiley +1 more source