Results 91 to 100 of about 693,970 (340)

YAP1::TFE3 mediates endothelial‐to‐mesenchymal plasticity in epithelioid hemangioendothelioma

open access: yesMolecular Oncology, EarlyView.
The YAP1::TFE3 fusion protein drives endothelial‐to‐mesenchymal transition (EndMT) plasticity, resulting in the loss of endothelial characteristics and gain of mesenchymal‐like properties, including resistance to anoikis, increased migratory capacity, and loss of contact growth inhibition in endothelial cells.
Ant Murphy   +9 more
wiley   +1 more source

Generalized Wintgen inequality for BI-SLANT submanifolds in conformal Sasakian space form with quarter-symmetric connection [PDF]

open access: yesArab Journal of Mathematical Sciences
Purpose – In 1979, P. Wintgen obtained a basic relationship between the extrinsic normal curvature the intrinsic Gauss curvature, and squared mean curvature of any surface in a Euclidean 4-space with the equality holding if and only if the curvature ...
Mohd Aslam   +2 more
doaj   +1 more source

On Sprays of Scalar Curvature and Metrizability

open access: yesThe Journal of Geometric Analysis, 2023
20 ...
openaire   +2 more sources

On the 2-scalar curvature [PDF]

open access: yesJournal of Differential Geometry, 2010
International ...
Ge, Yuxin   +2 more
openaire   +3 more sources

Emerging role of ARHGAP29 in melanoma cell phenotype switching

open access: yesMolecular Oncology, EarlyView.
This study gives first insights into the role of ARHGAP29 in malignant melanoma. ARHGAP29 was revealed to be connected to tumor cell plasticity, promoting a mesenchymal‐like, invasive phenotype and driving tumor progression. Further, it modulates cell spreading by influencing RhoA/ROCK signaling and affects SMAD2 activity. Rho GTPase‐activating protein
Beatrice Charlotte Tröster   +3 more
wiley   +1 more source

In vitro properties of patient serum predict clinical outcome after high dose rate brachytherapy of hepatocellular carcinoma

open access: yesMolecular Oncology, EarlyView.
Following high dose rate brachytherapy (HDR‐BT) for hepatocellular carcinoma (HCC), patients were classified as responders and nonresponders. Post‐therapy serum induced increased BrdU incorporation and Cyclin E expression of Huh7 and HepG2 cells in nonresponders, but decreased levels in responders.
Lukas Salvermoser   +14 more
wiley   +1 more source

On a type of spacetime [PDF]

open access: yesMathematica Moravica, 2014
The object of the present paper is to study a special type of spacetime. It is proved that in a conformally flat (W RS)4 spacetime with non-zero scalar curvature the vector field p defined by ɡ(X, p) = E(X) is irrotational and the integral curves of the ...
Mallick Sahanous, Chand De Uday
doaj  

The local moduli of Sasakian 3-manifolds

open access: yesInternational Journal of Mathematics and Mathematical Sciences, 2002
The Newman-Penrose-Perjes formalism is applied to Sasakian 3-manifolds and the local form of the metric and contact structure is presented. The local moduli space can be parameterised by a single function of two variables and it is shown that, given ...
Brendan S. Guilfoyle
doaj   +1 more source

Scalar curvature and projective compactness

open access: yesJournal of Geometry and Physics, 2015
Final version to be published in J. Geom. Phys. Includes minor typo corrections and a new summarising corollary.
Cap, Andreas, Gover, A. Rod
openaire   +3 more sources

Adaptaquin is selectively toxic to glioma stem cells through disruption of iron and cholesterol metabolism

open access: yesMolecular Oncology, EarlyView.
Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié   +16 more
wiley   +1 more source

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