Results 71 to 80 of about 13,851 (306)

Generalized Wintgen inequality for BI-SLANT submanifolds in conformal Sasakian space form with quarter-symmetric connection [PDF]

open access: yesArab Journal of Mathematical Sciences
Purpose – In 1979, P. Wintgen obtained a basic relationship between the extrinsic normal curvature the intrinsic Gauss curvature, and squared mean curvature of any surface in a Euclidean 4-space with the equality holding if and only if the curvature ...
Mohd Aslam   +2 more
doaj   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

open access: yesFEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa   +2 more
wiley   +1 more source

On a type of spacetime [PDF]

open access: yesMathematica Moravica, 2014
The object of the present paper is to study a special type of spacetime. It is proved that in a conformally flat (W RS)4 spacetime with non-zero scalar curvature the vector field p defined by ɡ(X, p) = E(X) is irrotational and the integral curves of the ...
Mallick Sahanous, Chand De Uday
doaj  

The local moduli of Sasakian 3-manifolds

open access: yesInternational Journal of Mathematics and Mathematical Sciences, 2002
The Newman-Penrose-Perjes formalism is applied to Sasakian 3-manifolds and the local form of the metric and contact structure is presented. The local moduli space can be parameterised by a single function of two variables and it is shown that, given ...
Brendan S. Guilfoyle
doaj   +1 more source

PARK(ing) time–How park deficiency affects the biological clock in a Drosophila model of Parkinson's disease

open access: yesFEBS Letters, EarlyView.
Drosophila park mutants serve as a model for Parkinson's disease. We used this strain to investigate the connection between oxidative stress and the circadian clock mechanism. We showed that increased oxidative stress affects the physiology of pacemaker cells, disrupting their daily structural plasticity. Lack of rhythmic signaling from pacemaker cells
Kamila Zientara   +3 more
wiley   +1 more source

Entire Scalar Curvature Flow and Hypersurfaces of Constant Scalar Curvature in Minkowski Space [PDF]

open access: yesMethods and Applications of Analysis, 2009
We prove existence in the Minkowski space of entire spacelike hypersurfaces with constant negative scalar curvature and given set of lightlike directions at infinity; we also construct the entire scalar curvature flow with prescribed set of lightlike directions at infinity, and prove that the flow converges to a spacelike hypersurface with constant ...
openaire   +3 more sources

Positive scalar curvature on manifolds with boundary and their doubles

open access: yes, 2022
This paper is about positive scalar curvature on a compact manifold $X$ with non-empty boundary $\partial X$. In some cases, we completely answer the question of when $X$ has a positive scalar curvature metric which is a product metric near $\partial X$,
Weinberger, Shmuel, Rosenberg, Jonathan
core   +1 more source

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

open access: yesMolecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce   +11 more
wiley   +1 more source

Deformation of the scalar curvature and the mean curvature

open access: yes, 2020
On a compact manifold $M$ with boundary $\partial M$, we study the problem of prescribing the scalar curvature in $M$ and the mean curvature on the boundary $\partial M$ simultaneously. To do this, we introduce the notion of singular metric, which is inspired by the early work of Fischer-Marsden in [18] and Lin-Yuan in [23] for closed manifold. We show
Ho, Pak Tung, Huang, Yen-Chang
openaire   +2 more sources

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

open access: yesMolecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat   +8 more
wiley   +1 more source

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