Results 111 to 120 of about 193,587 (326)

Weak scalar curvature lower bounds along Ricci flow [PDF]

open access: bronze, 2023
Wenshuai Jiang   +2 more
openalex   +1 more source

Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra   +6 more
wiley   +1 more source

RIPK4 function interferes with melanoma cell adhesion and metastasis

open access: yesMolecular Oncology, EarlyView.
RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski   +9 more
wiley   +1 more source

Inequality for Ricci curvature of certain submanifolds in locally conformal almost cosymplectic manifolds

open access: yesInternational Journal of Mathematics and Mathematical Sciences, 2005
We establish inequalities between the Ricci curvature and the squared mean curvature, and also between the k-Ricci curvature and the scalar curvature for a slant, semi-slant, and bi-slant submanifold in a locally conformal almost cosymplectic manifold ...
Dae Won Yoon
doaj   +1 more source

A geometric formulation of Higgs Effective Field Theory: Measuring the curvature of scalar field space

open access: yesPhysics Letters B, 2016
A geometric formulation of Higgs Effective Field Theory (HEFT) is presented. Experimental observables are given in terms of geometric invariants of the scalar sigma model sector such as the curvature of the scalar field manifold M.
Rodrigo Alonso   +2 more
doaj   +1 more source

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

open access: yesMolecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau   +36 more
wiley   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang   +12 more
wiley   +1 more source

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