Results 111 to 120 of about 378,031 (307)

Scalar curvatures onS n

open access: yesMathematische Annalen, 1989
The author studies the question whether a given smooth function K on \(S^ n\) is the scalar curvature of a metric conformal to the standard metric. Not all functions can be realized - obstructions have been found by Kazdan-Warner and Bourguignon-Ezin. The author gives various sufficient conditions, related to work of Escobar and Schoen, for a positive ...
openaire   +2 more sources

Somatostatin receptor 4 (SSTR4) is a tumor suppressor in cutaneous and head & neck squamous cell carcinomas

open access: yesMolecular Oncology, EarlyView.
This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi   +6 more
wiley   +1 more source

Profiling neoadjuvant therapy response in rectal cancer using meta‐analysis of publicly available transcriptomic RNA‐seq datasets

open access: yesMolecular Oncology, EarlyView.
This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic   +10 more
wiley   +1 more source

Scalar curvature, mass, and other asymptotic invariants

open access: yes, 2023
International audienceThis is a survey on asymptotic invariants of asymptotically flat or asymptotically hyperbolic manifolds, their geometric contents, their generalizations, and their connections with scalar curvature and other curvature ...
Herzlich, Marc
core   +1 more source

Extracellular vesicle lipidomics liquid biopsy reveals systemic and tumor microenvironment metabolic reprogramming in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Extracellular vesicle (EV) lipidomic profiling of plasma and ascites from patients with high‐grade serous ovarian cancer and of ovarian cancer cell lines reveals enrichment of triglycerides (TGs), diacylglycerols (DGs), phosphatidylcholine (PCs), sphingomyelins (SMs), reflecting tumor metabolic reprogramming.
Shikha Rani   +9 more
wiley   +1 more source

Predictive and prognostic biomarkers of Bacillus Calmette‐Guérin therapy failure in bladder cancer patients: A systematic review

open access: yesMolecular Oncology, EarlyView.
High‐risk bladder cancer is typically treated with Bacillus Calmette‐Guérin (BCG), but 30–40% of patients relapse. No FDA‐ or CE‐approved biomarkers currently predict or prognosticate BCG failure. We systematically reviewed the literature and identified 72 eligible studies, revealing several promising biomarkers associated with BCG treatment response ...
Rui Ribeiro‐Pereira   +7 more
wiley   +1 more source

Kinetic scalar curvature extended f(R) gravity

open access: yesNuclear Physics B, 2018
In this work we study a modified version of vacuum f(R) gravity with a kinetic term which consists of the first derivatives of the Ricci scalar. We develop the general formalism of this kinetic Ricci modified f(R) gravity and we emphasize on cosmological
S.V. Chervon   +4 more
doaj   +1 more source

Constant scalar curvature metrics on connected sums [PDF]

open access: yes, 2003
The Yamabe problem (proved in 1984) guarantees the existence of a metric of constant scalar curvature in each conformal class of Riemannian metrics on a compact manifold of dimension $n \geq 3$, which minimizes the total scalar curvature of this ...
Dominic Joyce
core   +1 more source

p190A/ARHGAP35 and p190B/ARHGAP5 proteins in endometrial cancer: a novel cancer‐relevant paralog interplay

open access: yesMolecular Oncology, EarlyView.
This study identifies ARHGAP5, in addition to the frequently mutated ARHGAP35, as significantly mutated in endometrial cancer. Mutations in both genes co‐occur and are associated with their correlated downregulation. Functional CRISPR studies show that both paralogs regulate similar pathways, including actin cytoskeleton organization.
Mathilde Pinault   +12 more
wiley   +1 more source

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