Results 111 to 120 of about 681,612 (344)

Data‐driven discovery of gene expression markers distinguishing pediatric acute lymphoblastic leukemia subtypes

open access: yesMolecular Oncology, EarlyView.
This study investigates gene expression differences between two major pediatric acute lymphoblastic leukemia (ALL) subtypes, B‐cell precursor ALL, and T‐cell ALL, using a data‐driven approach consisting of biostatistics and machine learning methods. Following analysis of a discovery dataset, we find a set of 14 expression markers differentiating the ...
Mona Nourbakhsh   +8 more
wiley   +1 more source

Asymptotic generalized extended uncertainty principle

open access: yesEuropean Physical Journal C: Particles and Fields, 2020
We present a formalism which allows for the perturbative derivation of the Extended Uncertainty Principle (EUP) for arbitrary spatial curvature models and observers.
Mariusz P. Da̧browski, Fabian Wagner
doaj   +1 more source

A Ricci flow proof of a result by Gromov on lower bounds for scalar curvature [PDF]

open access: yes, 2015
In this note we reprove a theorem of Gromov using Ricci flow. The theorem states that a, possibly non-constant, lower bound on the scalar curvature is stable under $C^0$-convergence of the metric.
R. Bamler
semanticscholar   +1 more source

Circle actions and scalar curvature [PDF]

open access: yesTransactions of the American Mathematical Society, 2015
25 pages; several changes according to comments of a referee made; to appear in Trans. Am.
openaire   +5 more sources

The anticancer effect of the HDAC inhibitor belinostat is enhanced by inhibitors of Bcl‐xL or Mcl‐1 in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
The pan‐HDAC inhibitor belinostat increases the expression of the pro‐apoptotic proteins Bim, Puma, and Noxa and induces apoptosis in ovarian cancer cell lines and patient‐derived tumor organoids when used at high concentrations. Moreover, inhibiting the anti‐apoptotic proteins Bcl‐xL or Mcl‐1 sensitizes these preclinical models to the cytotoxic effect
Cécilia Thomine   +10 more
wiley   +1 more source

On the moduli space curvature at infinity

open access: yesJournal of High Energy Physics
We analyse the scalar curvature of the vector multiplet moduli space M X VM $$ {\mathcal{M}}_X^{\textrm{VM}} $$ of type IIA string theory compactified on a Calabi-Yau manifold X.
Fernando Marchesano   +2 more
doaj   +1 more source

Erratum to: Total Scalar Curvature and Harmonic Curvature [PDF]

open access: yesTaiwanese Journal of Mathematics, 2016
It has been realized that the proof of Theorem 5.1 in Section 5 is imcomplete. It was pointed out by Professor Jongsu Kim and Israel Evangelista.
Yun, Gabjin   +2 more
openaire   +2 more sources

Systematic profiling of cancer‐fibroblast interactions reveals drug combinations in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Fibroblasts, cells in the tumor environment, support ovarian cancer cell growth and alter morphology and drug response. We used fibroblast and cancer cell co‐culture models to test 528 drugs and discovered new drugs for combination treatment. We showed that adding Vorinostat or Birinapant to standard chemotherapy may improve drug response, suggesting ...
Greta Gudoityte   +10 more
wiley   +1 more source

Entire Scalar Curvature Flow and Hypersurfaces of Constant Scalar Curvature in Minkowski Space [PDF]

open access: yesMethods and Applications of Analysis, 2009
We prove existence in the Minkowski space of entire spacelike hypersurfaces with constant negative scalar curvature and given set of lightlike directions at infinity; we also construct the entire scalar curvature flow with prescribed set of lightlike directions at infinity, and prove that the flow converges to a spacelike hypersurface with constant ...
openaire   +3 more sources

Comprehensive omics‐based classification system in adult patients with B‐cell acute lymphoblastic leukemia

open access: yesMolecular Oncology, EarlyView.
The COMBAT classification system, developed through multi‐omics integration, stratifies adult patients with B‐cell acute lymphoblastic leukemia(B‐ALL) into three molecular subtypes with distinct surface antigen patterns, immune landscape, methylation patterns, biological pathways and prognosis.
Yang Song   +11 more
wiley   +1 more source

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