Results 121 to 130 of about 192,579 (307)

LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro

open access: yesMolecular Oncology, EarlyView.
Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix   +13 more
wiley   +1 more source

Effective Gravitational “Constant” in Scalar-(Curvature)Tensor and Scalar-Torsion Gravities

open access: yesUniverse, 2017
In theories where a scalar field couples nonminimally to gravity, the effective gravitational “constant” becomes dependent on the value of the scalar field.
Laur Järv
doaj   +1 more source

Infinite loop spaces and positive scalar curvature [PDF]

open access: green, 2017
Boris Botvinnik   +2 more
openalex   +1 more source

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

open access: yesMolecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla   +10 more
wiley   +1 more source

Combining antibody conjugates with cytotoxic and immune‐stimulating payloads maximizes anti‐cancer activity

open access: yesMolecular Oncology, EarlyView.
Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang   +3 more
wiley   +1 more source

Multiply Warped Products with a Semisymmetric Metric Connection

open access: yesAbstract and Applied Analysis, 2014
We study the Einstein multiply warped products with a semisymmetric metric connection and the multiply warped products with a semisymmetric metric connection with constant scalar curvature, and we apply our results to generalized Robertson-Walker space ...
Yong Wang
doaj   +1 more source

Scalar curvature of spheres

open access: yesMathematische Zeitschrift, 1989
The author shows the following result: If \(m\not\equiv 1\) (Mod 4), and \(m\geq 4\), every smooth function of \(S^ m\) is the scalar curvature of some metric of unit total volume.
openaire   +2 more sources

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

open access: yesMolecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee   +8 more
wiley   +1 more source

Colliding scalar pulses in the Einstein-Gauss-Bonnet gravity

open access: yesEPJ Web of Conferences, 2018
We numerically investigated how the nonlinear dynamics depends on the dimensionality and on the higher-order curvature corrections in the form of Gauss-Bonnet (GB) terms, with a model of colliding scalar pulses in plane-symmetric space-time.
Shinkai Hisaaki, Torii Takashi
doaj   +1 more source

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